Luba Hunakova was born in Nitra, Slovakia, in 1967. She studied biophysics at the Faculty of Mathematics and Physics, Commenius University, Bratislava, graduating in 1990. She studied the lateral diffusion of lipids and proteins in biomembranes by FRAP in the laboratory of laser spectroscopy at Commenius University. She received the Ph.D. degree from the Cancer Research Institute, Slovak Academy of Sciences, Bratislava, in oncology, in 1996. Since 1990, she is working in the Tumor Immunology Laboratory of Cancer Research Institute. In 1997, she served as a Research Fellow in CRC Center for Cancer Therapeutics at the Institute of Cancer Research, Belmont, Sutton, UK (ICRETT). Since 1999, she serves as a Senior Scientist of CRI SAS, dealing with cell-surface antigens of normal and neoplastic cells, cell-cycle analysis, cell-surface phenotype after induction of differentiation, apoptosis, cell death, and modulation of drug resistance in a cytofluorometric laboratory. From 2000 to 2002, she worked at the National Institute of Environmental Health Sciences, USA, under the supervision of Professor V. Houten. Her studies on protein-DNA interactions consisted of spectroscopic studies on UvrABC-DNA interactions, thermodynamics, and kinetics. Her current research interests include drug- induced apoptosis, cell-cycle and cell-surface antigen alterations in human cancer cells, relationships between apoptosis, cell cycle, and DNA repair epithelial-mesenchymal transition, effect of natural compounds isothiocyanates (ITCs) on cellular mechanisms and markers associated with aggressive phenotype, and treatment responsiveness in breast and ovarian cancer.
Biography Updated on 23 February 2011