Nicolas Floquet received a Ph.D. degree and serves as a French CNRS Researcher since 2007. He is a specialist of computational methods (homology modeling, molecular dynamics, and normal mode analysis) used to decipher protein mechanics at the molecular scale, from their intrinsic motions to their interactions with small ligands or other protein partners (docking calculations). His skills include peptides, enzymes, and transmembrane receptors modeling, studied at different levels of complexity (all-atoms or coarse-grained simulations). Since 2007, he has been working on G-proteins coupled receptors (GPCRs), studying both their putative mechanism of activation and their interactions with ligands or G-proteins. Hypotheses from calculations are usually verified by either site-directed mutagenesis experiments and/or biophysical methods. Floquet received the Bronze Medal of CNRS in 2012.
Biography Updated on 12 September 2012