Philippe De Deurwaerdère0000-0002-1226-3516
Philippe De Deurwaerdère has bee working as a Professor of neurosciences since September 2011 at the University of Bordeaux, Talence Cedex, France and works in the CNRS Unit 5293 (Institute of Neurodegenerative Disease). Dr. De Deurwaerdère has made his Ph.D. thesis (1993-1997) under the supervision of Professor U Spampinato in the Laboratory of Professor M. Le Moal (INSERM U259, Bordeaux). He took a Postdoctoral position in Los Angeles (1999-2000) with Dr. Marie-Françoise Chesselet, and has known four research teams in Bordeaux since he has been nominated as Maitre de Conférence (Lecturer) in September 2000. His scientific work has been focused on the influence of the serotonin system on the activity of central dopamine neurons in the rat basal ganglia and particularly the role of 5-HT2C receptor. He has also addressed the influence of the serotonergic system in the rat model of Parkinson’s disease (Postdoc), notably in the mechanism of action of the antiparkinsonian drug L-DOPA. He has used and developed many technical approaches including intracerebral microdialysis, high-pressure liquid chromatography, immunohistochemistry, analysis of motor behaviours, in situ hybridization, and, more recently, extracellular single cell recordings. Today, Philippe De Deurwaerdère has published 39 papers in peer-reviewed journals, most of them being focused on the serotonin/dopamine interaction.
Biography Updated on 3 June 2012