Michael Doyle serves as a Senior Principle Investigator in the Department of Protein Science and Structure at Bristol-Myers Squibb Research and Development. His team is responsible for expression, purification, and biophysical characterization of discovery-stage protein therapeutic candidates and associated critical protein reagents. He earned his Ph.D. degree in protein biophysical chemistry from the University of Colorado Boulder and trained as a Postdoctoral Fellow at Washington University School of Medicine, working on protein biophysical chemistry. Prior to joining Bristol-Myers, he served as an Assistant Director at the Department of Macromolecular Sciences at GlaxoSmithKline, where his team was responsible for biophysical characterization of monoclonal antibody therapeutics, small molecule drug targets, and protein reagents. His research interests include characterization of the self-association and stability of proteins, quantitative molecular interaction analysis by surface plasmon resonance and isothermal titration calorimetry, and recombinant protein production. In 1997, he was awarded the Summer Young Scientist Award for Thermochemistry. In 2008–2009, he served as the President of the Association of Biomolecular Resource Facilities (ABRF), a nonprofit organization where he played other key leadership roles in establishing molecular interactions and recombinant protein production research groups. He worked on over 70 scientific articles in the area of protein biophysical characterization, and he serves on the Editorial Board of the Journal of Biomolecular Techniques and International Scholarly Research Network, Biochemistry.
Biography Updated on 29 December 2011