Yang Liu
Yang Liu obtained his Ph.D. degree at the Australian National University and postdoctoral training from Yale University. He has been on faculty in New York University, the Ohio State University, and currently at the University of Michigan at Ann Arbor. His research interest is on pathways and the controls of both cancer and autoimmunity.
Biography Updated on 12 July 2007
Articles in Scholarly Journals [Incomplete List]
- Immune competence of cancer-reactive T cells generated de novo in adult tumor-bearing mice
Blood, vol. 109, no. 1, pp. 253–258, 2007 - A Dinucleotide Deletion in CD24 Confers Protection against Autoimmune Diseases
PLoS Genetics, vol. 3, no. 4, p. e49, 2007 - Tumor growth impedes natural-killer-cell maturation in the bone marrow
Blood, vol. 108, no. 1, pp. 246–252, 2006 - Modeling of Charge Trapping Induced Threshold-Voltage Instability in High-$kappa$Gate Dielectric FETs
IEEE Electron Device Letters, vol. 27, no. 6, pp. 489–491, 2006 - Combination Therapy with Anti-CTL Antigen-4 and Anti-4-1BB Antibodies Enhances Cancer Immunity and Reduces Autoimmunity
Cancer Research, vol. 66, no. 14, pp. 7276–7284, 2006 - De novo Induction of a Cancer/Testis Antigen by 5-Aza-2'-Deoxycytidine Augments Adoptive Immunotherapy in a Murine Tumor Model
Cancer Research, vol. 66, no. 2, pp. 1105–1113, 2006 - Different Lineages of P1A-Expressing Cancer Cells Use Divergent Modes of Immune Evasion for T-Cell Adoptive Therapy
Cancer Research, vol. 66, no. 16, pp. 8241–8249, 2006 - Massive and destructive T cell response to homeostatic cue in CD24-deficient lymphopenic hosts
Journal of Experimental Medicine, vol. 203, no. 7, pp. 1713–1720, 2006 - Monte Carlo Pedigree Disequilibrium Test for Markers on the X Chromosome
The American Journal of Human Genetics, vol. 79, no. 3, pp. 567–573, 2006 - Nonlinear Force-Free Modeling of Coronal Magnetic Fields Part I: A Quantitative Comparison of Methods
Solar Physics, vol. 235, no. 1-2, pp. 161–190, 2006 - FoxP3: A genetic link between immunodeficiency and autoimmune diseases
Autoimmunity Reviews, vol. 5, no. 6, pp. 399–402, 2006 - Epm2a suppresses tumor growth in an immunocompromised host by inhibiting Wnt signaling
Cancer Cell, vol. 10, no. 3, pp. 179–190, 2006 - Harnessing the regulatory feedback to T cells to enhance antitumor immune responses
Drug Discovery Today: Therapeutic Strategies, vol. 3, no. 1, pp. 31–34, 2006 - Prediction of protein orientation upon immobilization on biological and nonbiological surfaces
Proceedings of the National Academy of Sciences, vol. 103, no. 40, pp. 14773–14778, 2006 - Dimerization of Laforin Is Required for Its Optimal Phosphatase Activity, Regulation of GSK3beta Phosphorylation, and Wnt Signaling
Journal of Biological Chemistry, vol. 281, no. 46, pp. 34768–34774, 2006 - Coupled optical and electronic simulations of electrically pumped photonic-crystal-based light-emitting diodes
Journal of Applied Physics, vol. 97, no. 4, p. 044503, 2005 - The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis
Journal of Experimental Medicine, vol. 202, no. 8, pp. 1141–1151, 2005 - Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells
Journal of Experimental Medicine, vol. 202, no. 11, pp. 1507–1516, 2005 - A Rare Transporter Associated with Antigen Processing Polymorphism Overpresented in HLAlow Colon Cancer Reveals the Functional Significance of the Signature Domain in Antigen Processing
Clinical Cancer Research, vol. 11, no. 10, pp. 3614–3623, 2005 - Human CTLA4 knock-in mice unravel the quantitative link between tumor immunity and autoimmunity induced by anti-CTLA-4 antibodies
Blood, vol. 106, no. 9, pp. 3127–3133, 2005 - Mode-locking of monolithic laser diodes incorporating coupled-resonator optical waveguides
Optics Express, vol. 13, no. 12, p. 4539, 2005 - Anti-human CTLA-4 monoclonal antibody promotes T-cell expansion and immunity in a hu-PBL-SCID model: a new method for preclinical screening of costimulatory monoclonal antibodies
Blood, vol. 105, no. 3, pp. 1114–1120, 2004 - Failed Adoptive Immunotherapy with Tumor-Specific T Cells: Reversal with Low-Dose Interleukin 15 but not Low-Dose Interleukin 2
Cancer Research, vol. 64, no. 21, pp. 8062–8067, 2004 - A new role for CD28 in the survival of autoreactive T cells in the periphery after chronic exposure to autoantigen
International Immunology, vol. 16, no. 10, pp. 1403–1409, 2004 - Transmembrane protein domains rarely use covalent domain recombination as an evolutionary mechanism
Proceedings of the National Academy of Sciences, vol. 101, no. 10, pp. 3495–3497, 2004 - Expression of tissue-specific autoantigens in the hematopoietic cells leads to activation-induced cell death of autoreactive T cells in the secondary lymphoid organs
European Journal of Immunology, vol. 34, no. 11, pp. 3126–3134, 2004 - Photospheric magnetic field observations during the May 12, 1997 CME and their implications for modeling that event
Journal of Atmospheric and Solar-Terrestrial Physics, vol. 66, no. 15-16, pp. 1283–1293, 2004 - CD24 Controls Expansion and Persistence of Autoreactive T Cells in the Central Nervous System during Experimental Autoimmune Encephalomyelitis
Journal of Experimental Medicine, vol. 200, no. 4, pp. 447–458, 2004 - CD24 Expression on T Cells Is Required for Optimal T Cell Proliferation in Lymphopenic Host
Journal of Experimental Medicine, vol. 200, no. 8, pp. 1083–1089, 2004 - CD24 is a genetic modifier for risk and progression of multiple sclerosis
Proceedings of the National Academy of Sciences, vol. 100, no. 25, pp. 15041–15046, 2003 - A Single-nucleotide Deletion Leads to Rapid Degradation of TAP-1 mRNA in a Melanoma Cell Line
Journal of Biological Chemistry, vol. 278, no. 17, pp. 15291–15296, 2003 - A 'PolyORFomic' Analysis of Prokaryote Genomes Using Disabled-homology Filtering Reveals Conserved But Undiscovered Short ORFs
Journal of Molecular Biology, vol. 333, no. 5, pp. 885–892, 2003 - CIITA-regulated plexin-A1 affects T-cell–dendritic cell interactions
Nature Immunology, vol. 4, no. 9, Article ID ni960, 7 pages, 2003 - Antigenic drift as a mechanism for tumor evasion of destruction by cytolytic T lymphocytes
Journal of Clinical Investigation, vol. 111, no. 10, pp. 1487–1496, 2003 - B7DC/PDL2 Promotes Tumor Immunity by a PD-1-independent Mechanism
Journal of Experimental Medicine, vol. 197, no. 12, pp. 1721–1730, 2003 - Two-signal requirement for activation and effector function of natural killer cell response to allogeneic tumor cells
Blood, vol. 102, no. 13, pp. 4456–4463, 2003 - Molecular Cancer, vol. 2, no. 1, p. 2, 2003
- B7-CTLA4 interaction promotes cognate destruction of tumor cells by cytotoxic T lymphocytes in vivo
Blood, vol. 99, no. 8, pp. 2880–2889, 2002 - In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells
Blood, vol. 100, no. 10, pp. 3633–3638, 2002 - Subcellular localization of the yeast proteome
Genes & Development, vol. 16, no. 6, pp. 707–719, 2002 - Cis elements for transporter associated with antigen-processing-2 transcription: two new promoters and an essential role of the IFN response factor binding element in IFN-gamma-mediated activation of the transcription initiator
International Immunology, vol. 14, no. 2, pp. 189–200, 2002 - Thermostability of membrane protein helix–helix interaction elucidated by statistical analysis
FEBS Letters, vol. 532, no. 1-2, pp. 231–236, 2002 - Perinatal Blockade of B7-1 and B7-2 Inhibits Clonal Deletion of Highly Pathogenic Autoreactive T Cells
Journal of Experimental Medicine, vol. 195, no. 8, pp. 959–971, 2002 - B7H Costimulates Clonal Expansion of, and Cognate Destruction of Tumor Cells by, CD8+ T Lymphocytes In Vivo
Journal of Experimental Medicine, vol. 194, no. 9, pp. 1339–1348, 2001 - Solar Physics, vol. 201, no. 2, pp. 337–355, 2001
- Cytotoxic T Lymphocytes to An Unmutated Tumor Rejection Antigen P1A: Normal Development but Restrained Effector Function In Vivo
Journal of Experimental Medicine, vol. 189, no. 5, pp. 811–820, 1999 - CD28-independent Induction of T Helper Cells and Immunoglobulin Class Switches Requires Costimulation by the Heat-stable Antigen
Journal of Experimental Medicine, vol. 187, no. 7, pp. 1151–1156, 1998 - B7-CTLA4 interaction enhances both production of antitumor cytotoxic T lymphocytes and resistance to tumor challenge
Proceedings of the National Academy of Sciences, vol. 95, no. 11, pp. 6284–6289, 1998 - Nature, vol. 396, no. 6709, pp. 373–376, 1998
- Identification of conserved amino acids in murine B7-1IgV domain critical for CTLA4/CD28:B7 interaction by site-directed mutagenesis: a novel structural model of the binding site
Molecular Immunology, vol. 35, no. 4, pp. 215–225, 1998 - Solar Physics, vol. 177, no. 1/2, pp. 395–410, 1998
- Solar Physics, vol. 180, no. 1/2, pp. 377–392, 1998
- Distinct Costimulatory Molecules Are Required for the Induction of Effector and Memory Cytotoxic T Lymphocytes
Journal of Experimental Medicine, vol. 185, no. 2, pp. 251–262, 1997 - CTLA-4-B7 Interaction Is Sufficient to Costimulate T Cell Clonal Expansion
Journal of Experimental Medicine, vol. 185, no. 7, pp. 1327–1336, 1997 - Costimulation by B7 Modulates Specificity of Cytotoxic T Lymphocytes: A Missing Link That Explains Some Bystander T Cell Activation
Journal of Experimental Medicine, vol. 186, no. 10, pp. 1787–1791, 1997 - Identification of a costimulatory molecule rapidly induced by CD40L as CD44H
Journal of Experimental Medicine, vol. 184, no. 3, pp. 955–961, 1996 - Gradients of the line-of-sight magnetic fields in active region NOAA 6659
Solar Physics, vol. 169, no. 1, pp. 79–89, 1996 - Signaling by a New Anti-Thy 1 Monoclonal Antibody Inhibits T Cell Proliferation and Interferes with T-Cell-Mediated Induction of Costimulatory Molecule B7-2
Cellular Immunology, vol. 165, no. 2, pp. 266–277, 1995 - Mutational analysis and an alternatively spliced product of B7 defines its CD28/CTLA4-binding site on immunoglobulin C-like domain
Journal of Experimental Medicine, vol. 181, no. 4, pp. 1345–1355, 1995 - T cell costimulation by B7/BB1 induces CD8 T cell-dependent tumor rejection: an important role of B7/BB1 in the induction, recruitment, and effector function of antitumor T cells
Journal of Experimental Medicine, vol. 179, no. 4, pp. 1205–1214, 1994 - Evolution of Vector Magnetic Field and White-Light Flares in a Solar Active Region (NOAA 6659) in 1991 June
The Astrophysical Journal, vol. 423, p. 828, 1994 - Heat-stable antigen is a costimulatory molecule for CD4 T cell growth
Journal of Experimental Medicine, vol. 175, no. 2, pp. 437–445, 1992