Isabelle Broutin has a formation of physicists she did at Orsay University, Paris, France. She obtained her Ph.D. degree from the Institute of Chemistry of the Natural Substances (ICSN), Paris, France (1989 –1993), on the X-ray structure determination of a cattle parasite serine collagenase protein. She performed a postdoctoral study at Professor A. Jones' Laboratory in Uppsala, Sweden, where she got formed to all the biophysics technics necessary for proteins production in purpose of crystallogenesis. She occupies a position at the National Center of Scientific Research (CNRS), France, since 1997, working on signal transduction pathways involving Grb2 protein. Dr. Broutin is specialized in protein crystallography and crystallogenesis. In 2000 she moved to Paris to participate in the creation of the Laboratoire de Cristallographie et RMN Biologiques (LCRB). She is now the Team Leader of the Signaling and membrane transport team lastly directed by Professor A. Ducruix. She now focuses her research on membrane proteins: (1) eukaryotic bitopic receptors involved in cancerization (PRLR, VEGFR), and (2) bacterial tripartite efflux pumps implicated in antibiotic resistance. Dr. Broutin is a Member of AFC (Association Française de Cristallographie) and SFBBM (Société Française de Biochimie et biologie Moléculaires).
Biography Updated on 6 October 2012