Vladimir Uversky

Vladimir N. Uversky received broad training, with the M.S. degree in physics, Leningrad State University, Russia, 1986, the Ph.D. degree from Moscow Institute of Technical Physics, 1991, and the D.S. degree in biophysics, Institute of Experimental and Theoretical Biophysics, Russian Academy of Sciences, 1998, and with pre- and postdoctoral research in structural biology, biochemistry, and biophysics (1991–1998, Institute of Protein Research, Russian Academy of Sciences). From 1985 until 1998, Dr. Uversky used a variety of biophysical and biochemical techniques to study molecular mechanisms of protein folding and to analyze structure and function of globular proteins. In 1998, he started to investigate protein misfolding. Working on protein folding-misfolding, Dr. Uversky found that many biologically active proteins do not have rigid structure and are often involved in human diseases. He is known for his work on structural characterization of partially folded proteins, for development of novel tools to study protein folding, misfolding and nonfolding, for studies on intrinsically disordered (or natively unfolded) proteins, and for a model of protein amyloidogenesis involving the premolten globular (disordered) state. While he continues to use biophysics and biochemistry, more recently Dr. Uversky has focused on the development and use of bioinformatics methods for the study of intrinsically disordered proteins.

Biography Updated on 25 September 2007

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