My research focuses on understanding molecular events coordinating the physiology of embryo implantation using the mouse and domestic ruminants as model organisms. Related to embryo implantation, we are specifically interested in the processes by which the embryo signals its presence as it invades the uterine wall in an effort to establish an exchange apparatus for nutrients and waste. As progesterone coordinates many of the aspects of embryo implantation, we are also interested in how ovarian-derived progesterone signals in the endometrium by non-classical mechanisms. In related studies, efforts are being made to learn how resident stem/progenitor cells of the endometrium contribute to uterine repair during the estrous/menstrual cycle and following parturition.
Biography Updated on 1 March 2012