C. Ioannides

C. Ioannides received a B.S. degree in biochemistry from the University of Liverpool, UK, in 1969, and a Ph.D. degree from the University of Surrey, UK, in 1973; in 1999, he was awarded a D.S. degree from the University of Liverpool. After spending sometime working for the Battelle Research, Institute in Geneva, Switzerland, he joined the University of Surrey as a member of staff in 1978, initially as an Experimental Officer and progressed to a Full Professor in 2003. The current themes of his research effort are the understanding of the interactions between chemical carcinogens and their likely impact on the risk assessment of mixtures, and the evaluation of the chemopreventive potential of phytochemicals, in particular isothiocyanates. He has published some 300 reviews and original research papers in peer-reviewed journals, and has edited 10 books in the areas of cytochromes P450 and xenobiotic metabolism. Currently, he is a member of the editorial board of Environmental Toxicology and associate editor of Xenobiotica.

Biography Updated on 11 February 2008

Personal Home Page

http://www.surrey.ac.uk/SBMS/ACADEMICS_homepage/_cv/Ioannides, Prof Costas.pdf

Articles in Scholarly Journals [Incomplete List]

  1. Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size
    Toxicology in Vitro, vol. 22, no. 1, pp. 128–145, 2008
  2. Evaluation of the precision-cut liver and lung slice systems for the study of induction of CYP1, epoxide hydrolase and glutathione S-transferase activities
    Toxicology, vol. 231, no. 1, pp. 68–80, 2007
  3. Mice convert melatonin to 6-sulphatoxymelatonin
    General and Comparative Endocrinology, vol. 147, no. 3, pp. 371–376, 2006
  4. Stability of cytochromes P450 and phase II conjugation systems in precision-cut rat lung slices cultured up to 72h
    Toxicology, vol. 224, no. 1-2, pp. 14–21, 2006
  5. Modulation of gene expression and DNA-adduct formation in precision-cut liver slices exposed to polycyclic aromatic hydrocarbons of different carcinogenic potency
    Mutagenesis, vol. 22, no. 1, pp. 55–62, 2006
  6. Cytochrome P450 Expression in the Liver of Food-Producing Animals
    Current Drug Metabolism, vol. 7, no. 4, pp. 335–348, 2006
  7. Black tea intake modulates the excretion of urinary mutagens in rats exposed to 6-aminochrysene: induction of cytochromes P450 by 6-aminochrysene in the rat
    Mutagenesis, vol. 20, no. 1, pp. 23–28, 2005
  8. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity
    International Journal of Cancer, vol. 117, no. 3, pp. 356–362, 2005
  9. Short-term black tea intake modulates the excretion of urinary mutagens in rats treated with 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ): role of CYP1A2 upregulation
    Archives of Toxicology, vol. 78, no. 8, 2004
  10. Functional integrity of precision-cut liver slices from deer and cattle
    Journal of Veterinary Pharmacology and Therapeutics, vol. 27, no. 2, pp. 79–84, 2004
  11. Metabolic and structural viability of precision-cut rat lung slices in culture
    Xenobiotica, vol. 34, no. 8, pp. 771–780, 2004
  12. An improved method for the extraction of mutagens from human urine and cooked meat using blue rayon
    Mutation Research/Genetic Toxicology and Environmental Mutagenesis, vol. 559, no. 1-2, pp. 121–130, 2004
  13. Hepatic and intestinal cytochrome P450 and conjugase activities in rats treated with black tea theafulvins and theaflavins
    Food and Chemical Toxicology, vol. 41, no. 8, pp. 1141–1147, 2003
  14. Cytochrome P450 expression and testosterone metabolism in the liver of deer
    Toxicology, vol. 187, no. 1, pp. 49–65, 2003
  15. Xenobiotic conjugation systems in deer compared with cattle and rat
    Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, vol. 134, no. 1, pp. 169–173, 2003
  16. Bioavailability of dietary doses of 3 H-labelled tea antioxidants (+)-catechin and (−)-epicatechin in rat
    Xenobiotica, vol. 33, no. 7, pp. 743–753, 2003
  17. Effects of black tea theafulvins on aflatoxin B1 mutagenesis in the Ames test
    Mutagenesis, vol. 18, no. 2, pp. 145–150, 2003
  18. Drug–phytochemical interactions
    Inflammopharmacology, vol. 11, no. 1, pp. 7–42, 2003
  19. A quantitative structure-activity relationship (QSAR) study of mutagenicity in several series of organic chemicals likely to be activated by cytochrome P450 enzymes
    Teratogenesis, Carcinogenesis, and Mutagenesis, vol. 23, no. S1, pp. 187–193, 2003
  20. Pharmacokinetic interactions between herbal remedies and medicinal drugs
    Xenobiotica, vol. 32, no. 6, pp. 451–478, 2002
  21. Evaluation of the antigenotoxic potential of monomeric and dimeric flavanols, and black tea polyphenols against heterocyclic amine-induced DNA damage in human lymphocytes using the Comet assay
    Mutation Research/Genetic Toxicology and Environmental Mutagenesis, vol. 515, no. 1-2, pp. 39–56, 2002
  22. Mutagenic activity of the glutathione S-transferase substrate 1-chloro-2,4-dinitrobenzene (CDNB) in the Salmonella mutagenicity assay
    Mutation Research/Genetic Toxicology and Environmental Mutagenesis, vol. 520, no. 1-2, pp. 119–124, 2002
  23. Mutagenicity of bay-region amino-substituted cyclopenta[a]phenanthrenes and 2- and 5-aminochrysene
    Mutation Research/Genetic Toxicology and Environmental Mutagenesis, vol. 492, no. 1-2, pp. 7–11, 2001
  24. Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices
    Journal of Pineal Research, vol. 31, no. 4, pp. 333–342, 2001
  25. The metabolism and bioactivation of agaritine and of other mushroom hydrazines by whole mushroom homogenate and by mushroom tyrosinase
    Toxicology, vol. 161, no. 3, pp. 165–177, 2001
  26. A study of the expression of the xenobiotic-metabolising cytochrome P450 proteins and of testosterone metabolism in bovine liver
    Biochemical Pharmacology, vol. 62, no. 5, pp. 635–645, 2001
  27. Effect of antioxidant flavonoids and a food mutagen on lymphocytes of a thalassemia patient without chelation therapy in the Comet assay
    Teratogenesis, Carcinogenesis, and Mutagenesis, vol. 21, no. 2, pp. 165–174, 2001
  28. Modulation of the mutagenicity of food carcinogens by oligomeric and polymeric procyanidins isolated from grape seeds: synergistic genotoxicity withN-nitrosopyrrolidine
    Journal of the Science of Food and Agriculture, vol. 80, no. 1, pp. 91–101, 2000
  29. Differential modulation of the genotoxicity of food carcinogens by naturally occurring monomeric and dimeric polyphenolics
    Environmental and Molecular Mutagenesis, vol. 35, no. 2, pp. 86–98, 2000
  30. Stability of cytochrome P450 proteins in cultured precision-cut rat liver slices
    Toxicology, vol. 149, no. 2-3, pp. 51–61, 2000
  31. Bioactivation of the carcinogen 11-methoxy-16,17-dihydro-15H-cyclopenta[a]phenanthrene
    Mutation Research/Genetic Toxicology and Environmental Mutagenesis, vol. 465, no. 1-2, pp. 85–90, 2000
  32. Fate of the Mushroom Hydrazine Agaritine in the Rat and Mouse
    Nutrition and Cancer, vol. 37, no. 1, pp. 55–64, 2000
  33. Effect of diet and nutrition on the expression of cytochromes P450
    Xenobiotica, vol. 29, no. 2, pp. 109–154, 1999
  34. Consumption of tea modulates the urinary excretion of mutagens in rats treated with IQ. Role of caffeine
    Mutation Research/Genetic Toxicology and Environmental Mutagenesis, vol. 441, no. 2, pp. 191–203, 1999
  35. Evidence for the presence of a microsomal NADH-dependent enzyme system that can bioactivate aromatic amines in the liver of rats and mice
    Toxicology, vol. 134, no. 2-3, pp. 127–141, 1999
  36. Proliferation of hepatic peroxisomes in rats following the intake of green or black tea
    Toxicology Letters, vol. 109, no. 1-2, pp. 69–76, 1999
  37. Stability of Phase II Conjugation Systems in Cultured Precision-cut Rat Hepatic Slices
    Toxicology in Vitro, vol. 13, no. 3, pp. 459–466, 1999
  38. Modulation of hepatic cytochrome P450 activity and carcinogen bioactivation by black and decaffeinated black tea
    Environmental Toxicology and Pharmacology, vol. 7, no. 1, pp. 41–47, 1999
  39. Impact of diseases on detoxication
    Journal of Biochemical and Molecular Toxicology, vol. 13, no. 3-4, pp. 215–218, 1999
  40. The substrate specificity of the rat hepatic cytosolic arylamine oxidase catalyzing the bioactivation of aromatic amines
    Cancer Letters, vol. 127, no. 1-2, pp. 141–146, 1998
  41. Marked inhibition of hepatic cytochrome P450 activity in cholesterol-induced atherosclerosis in rabbits
    Toxicology, vol. 126, no. 3, pp. 179–193, 1998
  42. Contribution of theafulvins to the antimutagenicity of black tea: their mechanism of action
    Mutagenesis, vol. 13, no. 6, pp. 631–636, 1998
  43. A combined COMPACT and HazardExpert study of 40 chemicals for which information on mutagenicity and carcinogenicity is known, including the results of human epidemiological studies
    Human & Experimental Toxicology, vol. 17, no. 10, pp. 577–586, 1998
  44. Diaminonaphthalenes and related aminocompounds: Mutagenicity, CYP1A induction and interaction with the Ah receptor
    Toxicology, vol. 118, no. 2-3, pp. 115–127, 1997
  45. Induction of the rat hepatic cytosolic arylamine oxidase by a series of polychlorinated biphenyls: association with the Ah locus
    Toxicology Letters, vol. 92, no. 2, pp. 81–91, 1997
  46. Bioactivation of mushroom hydrazines to mutagenic products by mammalian and fungal enzymes
    Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 381, no. 1, pp. 131–139, 1997
  47. Fractionation of green tea extracts: correlation of antimutagenic effect with flavanol content
    Journal of the Science of Food and Agriculture, vol. 75, no. 4, pp. 453–462, 1997
  48. Interaction with the Aromatic Hydrocarbon Receptor, CYP1A Induction, and Mutagenicity of a Series of Diaminotoluenes: Implications for Their Carcinogenicity
    Toxicology and Applied Pharmacology, vol. 139, no. 1, pp. 203–211, 1996
  49. Expression and inducibility of cytochrome P450 proteins in the liver of chick embryo
    Archives of Toxicology, vol. 71, no. 1-2, pp. 57–63, 1996
  50. Effect of vitamin C supplementation on hepatic cytochrome P450 mixed-function oxidase activity in streptozotocin-diabetic rats
    Toxicology Letters, vol. 89, no. 3, pp. 249–256, 1996
  51. Defective expression of cytochrome P450 proteins in the liver of the genetically obese Zucker rat
    European Journal of Pharmacology: Environmental Toxicology and Pharmacology, vol. 293, no. 4, pp. 385–393, 1995
  52. Computer graphics analysis of the interaction of alkoxy methylenedioxybenzenes with cytochromes P4501
    Toxicology Letters, vol. 76, no. 1, pp. 39–45, 1995
  53. Induction of hepatic CYP1A2 by the oral administration of caffeine to rats: lack of association with the Ah locus
    Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol. 1272, no. 2, pp. 89–94, 1995
  54. A quantitative structure-activity relationship study on a series of 10 para-substituted toluenes binding to cytochrome P4502B4 (CYP2B4), and their hydroxylation rates
    Biochemical Pharmacology, vol. 50, no. 5, pp. 619–625, 1995
  55. Expression and Inducibility of Cytochrome-P450 Proteins Belonging to Families2,3 and 4 in the Rabbit Aorta
    Biochemical and Biophysical Research Communications, vol. 213, no. 3, pp. 916–921, 1995
  56. CYP1 induction, binding to the hepatic aromatic hydrocarbon receptor and mutagenicity of a series of 11-alkoxy cyclopenta[a]phenanthren-17-ones: a structure activity relationship
    Toxicology, vol. 95, no. 1-3, pp. 27–35, 1995
  57. Evaluation of the antimutagenic potential of anthracene: in vitro and ex vivo studies
    Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 309, no. 1, pp. 101–107, 1994
  58. Safety evaluations of food chemicals by “compact” 1. A study of some acyclic terpenes
    Food and Chemical Toxicology, vol. 32, no. 11, pp. 1053–1059, 1994
  59. Induction of hepatic microsomal CYP4A activity and of peroxisomal ß-oxidation by two non-steroidal anti-inflammatory drugs
    Archives of Toxicology, vol. 68, no. 2, pp. 73–78, 1994
  60. Modulation of the rat hepatic cytochrome P450 composition by long-term streptozotocin-induced insulin-dependent diabetes
    Journal of Biochemical Toxicology, vol. 9, no. 2, pp. 63–69, 1994
  61. Molecular modelling of cytochrome CYP1A1: a putative access channel explains differences in induction potency between the isomers benzo(a)pyrene and benzo(e)pyrene, and 2- and 4-acetylaminofluorene
    Toxicology Letters, vol. 71, no. 3, pp. 235–243, 1994
  62. The Effects of Nutrition on Chemical Toxicity
    Drug Metabolism Reviews, vol. 26, no. 4, pp. 739–765, 1994
  63. Molecular Modeling of Enzymes and Receptors Involved in Carcinogenesis: Qsars and Compacted-3D
    Drug Metabolism Reviews, vol. 26, no. 1, pp. 261–285, 1994
  64. Induction of Cytochrome P4501 as an Indicator of Potential Chemical Carcinogenesis
    Drug Metabolism Reviews, vol. 25, no. 4, pp. 485–501, 1993
  65. The metabolism and activation of 15,16-dihydrocyclopental[a]phenanthren-17-one by cytochrome P-450 proteins
    European Journal of Pharmacology: Environmental Toxicology and Pharmacology, vol. 228, no. 5-6, pp. 275–282, 1993
  66. Chemical Research in Toxicology, vol. 6, no. 4, pp. 535–541, 1993
  67. Sex differences in the diabetes-induced modulation of rat hepatic cytochrome p450 proteins
    Biochemical Pharmacology, vol. 45, no. 2, pp. 313–319, 1993
  68. Effects of ether anaesthesia and fasting on various cytochromes P450 of rat liver and kidney
    Biochemical Pharmacology, vol. 45, no. 4, pp. 871–877, 1993
  69. Contribution of phenolic and quinonoid structures in the mutagenicity of the edible mushroom Agaricus bisporus
    Food and Chemical Toxicology, vol. 31, no. 8, pp. 561–567, 1993
  70. Validation of a novel molecular orbital approach (COMPACT) for the prospective safety evaluation of chemicals, by comparison with rodent carcinogenicity and Salmonella mutagenicity data evaluated by the U.S. NCI/NTP
    Mutation Research/Environmental Mutagenesis and Related Subjects, vol. 291, no. 1, pp. 61–77, 1993
  71. Mutagenicity of chrysene, its methyl and benzo derivatives, and their interactions with cytochromes P-450 and the Ah-receptor; relevance to their carcinogenic potency
    Toxicology, vol. 81, no. 1, pp. 69–86, 1993
  72. A cytosolic oxygenase activity involved in the bioactivation of 2-aminofluorene
    Toxicology, vol. 71, no. 1-2, pp. 7–20, 1992
  73. Molecular pathology of drug-disease interactions in chronic autoimmune inflammatory diseases
    Inflammopharmacology, vol. 1, no. 1, pp. 3–36, 1991
  74. Feprazone: An inducer of the P450 II B family of proteins in the rat
    Journal of Biochemical Toxicology, vol. 5, no. 1, pp. 9–12, 1990
  75. Adverse reactions of imidazole antifungal agents: Computer graphic studies of cytochrome P-450 interactions
    Journal of Biochemical Toxicology, vol. 4, no. 4, pp. 231–234, 1989
  76. Metabolic activation of chemical carcinogens by hepatic preparations from streptozotocin-treated rats
    Diabetologia, vol. 32, no. 2, pp. 135–139, 1989
  77. Induction of the rat hepatic microsomal mixed-function oxidases by cimetidine
    Toxicology Letters, vol. 49, no. 1, pp. 61–68, 1989
  78. Prediction of chemical carcinogenicity from molecular and electronic structures: a comparison of MINDO/3 and CNDO/2 molecular orbital methods
    Toxicology Letters, vol. 45, no. 1, pp. 1–13, 1989
  79. Molecular orbital studies of oxygen activation and mechanisms of cytochromes P-450-mediated oxidative metabolism of xenobiotics
    Chemico-Biological Interactions, vol. 70, no. 3-4, pp. 263–280, 1989
  80. Organic nitrate reductase: Reassessment of its subcellular localization and tissue distribution and its relationship to the glutathione transferases
    International Journal of Biochemistry, vol. 21, no. 1, pp. 67–71, 1989
  81. Metabolic action of polycyclic aromatic hydrocarbons to mutagens in the Ames test by various animal species including man
    Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 211, no. 1, pp. 147–151, 1989
  82. Preferential induction of the rat hepatic P450 I proteins by the food carcinogen 2-amino-3-methyl-imidazo[4,5-f]quinoline
    European Journal of Biochemistry, vol. 181, no. 3, pp. 627–631, 1989
  83. A Study of the Mutagenicity of Melatonin and 6-Hydroxymelatonin
    Journal of Pineal Research, vol. 6, no. 1, pp. 73–76, 1989
  84. Streptozotocin-induced diabetes modulates the metabolic activation of chemical carcinogens
    Chemico-Biological Interactions, vol. 68, no. 3-4, pp. 189–202, 1988
  85. Induction of rat hepatic cytochrome P-450 I proteins by the antimutagen anthraflavic acid
    Food and Chemical Toxicology, vol. 26, no. 11-12, pp. 909–915, 1988
  86. Induction of the rat hepatic microsomal mixed-function oxidases by 3 imidazole-containing antifungal agents: selectivity for the cytochrome P-450IIB and P-450III families of cytochromes P-450
    Toxicology, vol. 50, no. 3, pp. 283–301, 1988
  87. Role of ketone bodies in the diabetes-induced changes in hepatic mixed-function oxidase activities
    Biochimica et Biophysica Acta (BBA) - General Subjects, vol. 967, no. 2, pp. 250–254, 1988
  88. Induction of the rat hepatic microsomal mixed-function oxidases by two aza-arenes A comparison with their non-heterocyclic analogues
    Biochemical Pharmacology, vol. 37, no. 23, pp. 4565–4571, 1988
  89. The cytochromes P-448—A unique family of enzymes involved in chemical toxicity and carcinogenesis
    Biochemical Pharmacology, vol. 36, no. 24, pp. 4197–4207, 1987
  90. Interactions of imidazole antifungal agents with purified cytochrome P-450 proteins
    Biochemical Pharmacology, vol. 36, no. 24, pp. 4277–4281, 1987
  91. Anthraflavic acid is a potent and specific inhibitor of cytochrome P-448 activity
    Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, vol. 916, no. 3, pp. 328–331, 1987
  92. Structural requirements for substrates of cytochromes P-450 and P-448
    Chemico-Biological Interactions, vol. 64, no. 1-2, pp. 39–60, 1987
  93. Alkoxyresorufin O-dealkylases: Association with the murine Ah locus
    Cancer Letters, vol. 32, no. 3, pp. 255–262, 1986
  94. Molecular dimensions of the substrate binding site of cytochrome P-448
    Biochemical Pharmacology, vol. 35, no. 13, pp. 2179–2185, 1986
  95. Induction of cytochrome P-448 activity as exemplified by the O-deethylation of ethoxyresorufin Effects of dose, sex, tissue and animal species
    Biochemical Pharmacology, vol. 35, no. 21, pp. 3879–3884, 1986
  96. Hepatic microsomal mixed-function oxidase activity in ethanol-treated hamsters and its consequences on the bioactivation of aromatic amines to mutagens
    Chemico-Biological Interactions, vol. 59, pp. 129–139, 1986
  97. Interactions of safrole and isosafrole and their metabolites with cytochromes -450
    Chemico-Biological Interactions, vol. 53, pp. 303–311, 1985
  98. Metabolic activation of nitrosamines to mutagens by various animal species including man
    Biochemical Pharmacology, vol. 34, no. 3, pp. 441–442, 1985
  99. Mechanism of the protective action of n-acetylcysteine and methionine against paracetamol toxicity in the hamster
    Archives of Toxicology, vol. 57, no. 3, pp. 173–177, 1985
  100. Foetal and neonatal development of cytochrome P-450 and cytochrome P-448 catalysed mixed function oxidases in the rat: Induction by 3-methylcholanthrene
    Toxicology, vol. 35, no. 4, pp. 307–317, 1985
  101. The modulation by arylamines of the in vitro formation of superoxide anion radicals and hydrogen peroxide by rat liver microsomes
    Toxicology Letters, vol. 25, no. 2, pp. 121–130, 1985
  102. The homogeneity of rat liver microsomal cytochrome P-448 activity and its role in the activation of benzo[a]pyrene to mutagens
    International Journal of Biochemistry, vol. 17, no. 1, pp. 37–42, 1985
  103. Inhibition of rat hepatic mixed function oxidases by antimalarial drugs: Selectivity for cytochromes P-450 and P-448
    Chemico-Biological Interactions, vol. 51, no. 3, pp. 285–294, 1984
  104. Acute toxicity of 3-deoxy-4-sulphohexosulose in rats and mice, and in vitro mutagenicity in the ames test
    Food and Chemical Toxicology, vol. 21, no. 3, pp. 299–303, 1983
  105. Activation of aromatic amines to mutagens by various animal species including man
    Mutation Research/Genetic Toxicology, vol. 124, no. 3-4, pp. 325–336, 1983
  106. A comparison of the protective effects of N-acetylcysteine and S-carboxymethylcysteine against paracetamol-induced hepatotoxicity
    Toxicology, vol. 28, no. 4, pp. 313–321, 1983
  107. Species variation in the metabolic activation of paracetamol to toxic intermediates: Role of cytochromes P-450 and P-448
    Toxicology Letters, vol. 16, no. 1-2, pp. 55–61, 1983
  108. The role of highly purified forms of rat liver cytochrome P-450 in the demethylation of dimethylnitrosamine and its activation to mutagens
    Toxicology Letters, vol. 17, no. 1-2, pp. 131–135, 1983
  109. Effect of some ß-adrenergic blocking agents on tissue guanylate cyclase and cyclic nucleotides in the rat
    Toxicology Letters, vol. 18, no. 3, pp. 235–240, 1983
  110. Studies on the possible mutagenicity of ß-adrenergic blocker drugs
    Toxicology Letters, vol. 16, no. 3-4, pp. 167–174, 1983
  111. The mutagenic and cell transforming properties of shikimic acid and some of its bacterial and mammalian metabolites
    Toxicology Letters, vol. 19, no. 1-2, pp. 43–50, 1983
  112. Effect of deuteration of imipramine on its pharmacokinetic properties in the rat
    Biochemical Pharmacology, vol. 32, no. 4, pp. 641–647, 1983
  113. Inhibition of gastrointestinal mucosal glycoprotein synthesis by the ß-adrenergic blocking drug, practolol
    Biochemical Pharmacology, vol. 31, no. 13, pp. 2263–2266, 1982
  114. Selective inhibition of the safrole-induced mixed-function oxidase activities by 9-hydroxyellipticine
    Chemico-Biological Interactions, vol. 42, no. 3, pp. 279–289, 1982
  115. Metabolic activation of dimethylnitrosamine to mutagens: Role of cytochromes P-450 and P-448
    Toxicology Letters, vol. 11, no. 1-2, pp. 95–101, 1982
  116. Safrole: Its metabolism, carcinogenicity and interactions with cytochrome P-450
    Food and Cosmetics Toxicology, vol. 19, pp. 657–666, 1981
  117. Inhibition of cytochrome P-448 mixed function oxidase activity following administration of 9-hydroxyellipticine to rats
    Chemico-Biological Interactions, vol. 32, no. 1-2, pp. 101–110, 1980
  118. Drug metabolism in the ferret: Effects of age, sex and strain
    General Pharmacology: The Vascular System, vol. 8, no. 4, pp. 243–249, 1977
  119. The effect of allyl compounds on hepatic microsomal mixed function oxidation and porphyrogenesis
    Chemico-Biological Interactions, vol. 14, no. 3-4, pp. 241–249, 1976
  120. Improvement of barbiturate gas chromatography by formic acid: Possible mechanism
    Chromatographia, vol. 7, no. 7, pp. 351–356, 1974