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B. Staels
Institut Pasteur de Lille, France
Articles in Scholarly Journals [Incomplete List]
PPARs/RXRs in Cardiovascular Physiology and Disease
PPAR Research, vol. 2008, Article ID 173780, 1 pages, 2008
Inhibition of progesterone production in human luteinized granulosa cells treated with LXR agonists
Molecular Human Reproduction, vol. 13, no. 6, pp. 373–379, 2007
Drug Insight: mechanisms of action and therapeutic applications for agonists of peroxisome proliferator-activated receptors
Nature Clinical Practice Endocrinology & Metabolism, vol. 3, no. 2, Article ID ncpendmet0397, 11 pages, 2007
Safety issues and prospects for future generations of PPAR modulators
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol. 1771, no. 8, pp. 1065–1081, 2007
IP receptor-dependent activation of PPAR? by stable prostacyclin analogues
Biochemical and Biophysical Research Communications, vol. 360, no. 4, pp. 821–827, 2007
PPARd, but not PPARa, activates PGC-1a gene transcription in muscle
Biochemical and Biophysical Research Communications, vol. 354, no. 4, pp. 1021–1027, 2007
Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor a agonists
Bioorganic & Medicinal Chemistry Letters, vol. 17, no. 16, pp. 4689–4693, 2007
PPAR? Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties
Cell Metabolism, vol. 6, no. 2, pp. 137–143, 2007
The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor
Molecular and Cellular Endocrinology, vol. 270, no. 1-2, pp. 23–32, 2007
FXR: a promising target for the metabolic syndrome?
Trends in Pharmacological Sciences, vol. 28, no. 5, pp. 236–243, 2007
The PPAR?? Activator Fenofibrate Slows Down the Progression of the Left Ventricular Dysfunction in Porcine Tachycardia-Induced Cardiomyopathy
Journal of Cardiovascular Pharmacology, vol. 49, no. 6, pp. 408–415, 2007
IAP Survivin Regulates Atherosclerotic Macrophage Survival
Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 27, no. 4, pp. 901–907, 2007
The orphan nuclear receptor Rev-erb??: a transcriptional link between circadian rhythmicity and cardiometabolic disease
Current Opinion in Lipidology, vol. 18, no. 2, p. 141???146, 2007
Bile acids, farnesoid X receptor, atherosclerosis and metabolic control
Current Opinion in Lipidology, vol. 18, no. 3, p. 289???297, 2007
Peroxisome Proliferator-Activated Receptors Mediate Pleiotropic Actions of Statins
Circulation Research, vol. 100, no. 10, pp. 1394–1395, 2007
Liver X Receptor Activation Potentiates the Lipopolysaccharide Response in Human Macrophages
Circulation Research, vol. 101, no. 1, pp. 40–49, 2007
Retinoid-related orphan receptor regulates several genes that control metabolism in skeletal muscle cells: links to modulation of reactive oxygen species production
Journal of Molecular Endocrinology, vol. 39, no. 1, pp. 29–44, 2007
Bile???Acid???Sequestrants???and???the???Treatment of Type??2??Diabetes??Mellitus
Drugs, vol. 67, no. 10, pp. 1383–1392, 2007
PPAR Agonists Suppress Osteopontin Expression in Macrophages and Decrease Plasma Levels in Patients With Type 2 Diabetes
Diabetes, vol. 56, no. 6, pp. 1662–1670, 2007
Genetically-engineered animals as research models for atherosclerosis : their use for the characterization of PPAR agonists in the treatment of cardiometabolic disorders
Frontiers in Bioscience, vol. 12, no. 8-12, p. 4132, 2007
Inter-subject differences in constitutive expression levels of the clock gene in man.
Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease, vol. 4, no. 1, p. 39, 2007
Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human -Cells and Adipose Tissue and Strong Association With Type 2 Diabetes
Diabetes, vol. 55, no. 10, pp. 2903–2908, 2006
Peroxisome Proliferator-Activated Receptor � Improves Pancreatic Adaptation to Insulin Resistance in Obese Mice and Reduces Lipotoxicity in Human Islets
Diabetes, vol. 55, no. 6, pp. 1605–1613, 2006
Selective PPAR modulators, dual and pan PPAR agonists: multimodal drugs for the treatment of Type 2 diabetes and atherosclerosis
Expert Opinion on Emerging Drugs, vol. 11, no. 3, pp. 379–401, 2006
Peroxisome Proliferator-Activated Receptor and Adipose Tissue--Understanding Obesity-Related Changes in Regulation of Lipid and Glucose Metabolism
Journal of Clinical Endocrinology & Metabolism, vol. 92, no. 2, pp. 386–395, 2006
Metformin and pioglitazone: effectively treating insulin resistance
Current Medical Research and Opinion, vol. 22, no. 1, pp. 27–37, 2006
FXR: More than a Bile Acid Receptor?
Endocrinology, vol. 147, no. 9, pp. 4022–4024, 2006
Intestinal ABCA1 directly contributes to HDL biogenesis in vivo
Journal of Clinical Investigation, vol. 116, no. 4, pp. 1052–1062, 2006
Modulation of Hepatic Inflammatory Risk Markers of Cardiovascular Diseases by PPAR- Activators: Clinical and Experimental Evidence
Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, no. 5, pp. 977–986, 2006
The RXR Agonist Bexarotene Improves Cholesterol Homeostasis and Inhibits Atherosclerosis Progression in a Mouse Model of Mixed Dyslipidemia
Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, no. 12, pp. 2731–2737, 2006
Effect of Rosiglitazone Treatment on Plaque Inflammation and Collagen Content in Nondiabetic Patients: Data From a Randomized Placebo-Controlled Trial
Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, no. 4, pp. 845–850, 2006
Acute Antiinflammatory Properties of Statins Involve Peroxisome Proliferator-Activated Receptor-? via Inhibition of the Protein Kinase C Signaling Pathway
Circulation Research, vol. 98, no. 3, pp. 361–369, 2006
Both Hepatic and Extrahepatic ABCA1 Have Discrete and Essential Functions in the Maintenance of Plasma High-Density Lipoprotein Cholesterol Levels In Vivo
Circulation, vol. 114, no. 12, pp. 1301–1309, 2006
Cholesterol 7 -Hydroxylase Deficiency in Mice on an APOE*3-Leiden Background Increases Hepatic ABCA1 mRNA Expression and HDL-Cholesterol
Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, no. 12, pp. 2724–2730, 2006
Sorting out the roles of PPAR? in energy metabolism and vascular homeostasis
Journal of Clinical Investigation, vol. 116, no. 3, pp. 571–580, 2006
TReP-132 Is a Novel Progesterone Receptor Coactivator Required for the Inhibition of Breast Cancer Cell Growth and Enhancement of Differentiation by Progesterone
Molecular and Cellular Biology, vol. 26, no. 20, pp. 7632–7644, 2006
Human retinoic acid receptor-related orphan receptor ?1 overexpression protects neurones against oxidative stress-induced apoptosis
Journal of Neurochemistry, vol. 96, no. 6, pp. 1778–1789, 2006
Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPAR? agonists
Bioorganic & Medicinal Chemistry, vol. 14, no. 22, pp. 7377–7391, 2006
Studies towards the conception of new selective PPARß/d ligands
Bioorganic & Medicinal Chemistry Letters, vol. 16, no. 17, pp. 4528–4532, 2006
Peroxisome Proliferator-Activated Receptors at the Crossroads of Obesity, Diabetes, and Cardiovascular Disease
Journal of the American College of Cardiology, vol. 48, no. 9, pp. A24–A32, 2006
The expanding role of the bile acid receptor FXR in the small intestine
Journal of Hepatology, vol. 44, no. 6, pp. 1213–1215, 2006
PPARa and PPAR? dual agonists for the treatment of type 2 diabetes and the metabolic syndrome
Current Opinion in Pharmacology, vol. 6, no. 6, pp. 606–614, 2006
Transcriptional regulation of macrophage cholesterol trafficking by PPARa and LXR
Biochemical Society Transactions, vol. 34, no. 6, p. 1128, 2006
When the Clock stops ticking, metabolic syndrome explodes
Nature Medicine, vol. 12, no. 1, Article ID nm0106-54, 1 pages, 2006
Niemann–Pick C1 like 1 gene expression is down-regulated by LXR activators in the intestine
Biochemical and Biophysical Research Communications, vol. 340, no. 4, pp. 1259–1263, 2006
The liver X-receptor alpha controls hepatic expression of the human bile acid–glucuronidating UGT1A3 enzyme in human cells and transgenic mice
Hepatology, vol. 44, no. 2, pp. 368–378, 2006
[4-(2H-1,2,3-Benzotriazol-2-yl)phenoxy]alkanoic Acids as Agonists of Peroxisome Proliferator-Activated Receptors (PPARs)
Chemistry & Biodiversity, vol. 3, no. 4, pp. 385–395, 2006
Hepatic PCSK9 Expression Is Regulated by Nutritional Status via Insulin and Sterol Regulatory Element-binding Protein 1c
Journal of Biological Chemistry, vol. 281, no. 10, pp. 6211–6218, 2006
The Farnesoid X Receptor Modulates Adiposity and Peripheral Insulin Sensitivity in Mice
Journal of Biological Chemistry, vol. 281, no. 16, pp. 11039–11049, 2006
International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors
Pharmacological Reviews, vol. 58, no. 4, pp. 726–741, 2006
Paullinia pinnata Extracts Rich in Polyphenols Promote Vascular Relaxation via Endothelium-dependent Mechanisms
Journal of Cardiovascular Pharmacology, vol. 47, no. 4, pp. 599–608, 2006
PPAR: a new pharmacological target for neuroprotection in stroke and neurodegenerative diseases
Biochemical Society Transactions, vol. 34, no. 6, p. 1341, 2006
A fully dissociated compound of plant origin for inflammatory gene repression
Proceedings of the National Academy of Sciences, vol. 102, no. 44, pp. 15827–15832, 2005
The Farnesoid X Receptor: A Molecular Link Between Bile Acid and Lipid and Glucose Metabolism
Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 25, no. 10, pp. 2020–2030, 2005
TReP-132 Controls Cell Proliferation by Regulating the Expression of the Cyclin-Dependent Kinase Inhibitors p21WAF1/Cip1 and p27Kip1
Molecular and Cellular Biology, vol. 25, no. 11, pp. 4335–4348, 2005
Insulin-Mediated Down-Regulation of Apolipoprotein A5 Gene Expression through the Phosphatidylinositol 3-Kinase Pathway: Role of Upstream Stimulatory Factor
Molecular and Cellular Biology, vol. 25, no. 4, pp. 1537–1548, 2005
The Farnesoid X Receptor Modulates Hepatic Carbohydrate Metabolism during the Fasting-Refeeding Transition
Journal of Biological Chemistry, vol. 280, no. 33, pp. 29971–29979, 2005
Role of the PPAR family of nuclear receptors in the regulation of metabolic and cardiovascular homeostasis: new approaches to therapy
Current Opinion in Pharmacology, vol. 5, no. 2, pp. 177–183, 2005
Fluid retention mediated by renal PPAR
Cell Metabolism, vol. 2, no. 2, pp. 77–78, 2005
Pro-inflammatory properties for thiazolidinediones
Biochemical Pharmacology, vol. 69, no. 2, pp. 255–265, 2005