Brian Wigdahl

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http://www.drexelmed.edu/DepartmentsCentersandInstitutes/BasicScienceDepts/MicrobiologyImmunology/Faculty/BrianWigdahl/tabid/1196/Default.aspx

Articles in Scholarly Journals [Incomplete List]

  1. Induction of pro-inflammatory cytokines by human T-cell leukemia virus type-1 Tax protein as determined by multiplexed cytokine protein array analyses of human dendritic cells
    Biomedicine & Pharmacotherapy, vol. 61, no. 4, pp. 201–208, 2007
  2. Interaction of HTLV-1 Tax protein with calreticulin: Implications for Tax nuclear export and secretion
    Biomedicine & Pharmacotherapy, vol. 61, no. 4, pp. 194–200, 2007
  3. Identification of Human T Cell Leukemia Virus Type 1 Tax Amino Acid Signals and Cellular Factors Involved in Secretion of the Viral Oncoprotein
    Journal of Biological Chemistry, vol. 282, no. 47, pp. 34581–34593, 2007
  4. A novel high throughput quantum dot-based fluorescence assay for quantitation of virus binding and attachment?
    Journal of Virological Methods, vol. 141, no. 2, pp. 125–132, 2007
  5. Modulation of dendritic cell maturation and function by the Tax protein of human T cell leukemia virus type 1
    Journal of Leukocyte Biology, vol. 82, no. 1, pp. 44–56, 2007
  6. Dendritic cells in autoimmune diseases and neuroinflammatory disorders
    Frontiers in Bioscience, vol. 12, no. 8-12, p. 4315, 2007
  7. New insights into the pathogenesis, diagnosis and treatment of human T-cell leukemia virus type 1-induced disease
    Future Virology, vol. 2, no. 5, pp. 481–493, 2007
  8. Effects of Highly Active Antiretroviral Therapy on HIV-1-Associated Oral Complications
    Current HIV Research, vol. 5, no. 3, pp. 281–292, 2007
  9. PMA-Induced Differentiation of a Bone Marrow Progenitor Cell Line Activates HIV-1 LTR-Driven Transcription
    DNA and Cell Biology, vol. 26, no. 6, pp. 387–394, 2007
  10. Regulation of Human T-Cell Leukemia Virus Type 1 Gene Expression by Sp1 and Sp3 Interaction with TRE-1 Repeat III
    DNA and Cell Biology, vol. 25, no. 5, pp. 262–276, 2006
  11. Use of human antigen presenting cell gene array profiling to examine the effect of human T-cell leukemia virus type 1 Tax on primary human dendritic cells
    Journal of NeuroVirology, vol. 12, no. 1, pp. 47–59, 2006
  12. Critical Design Features of Phenyl Carboxylate-Containing Polymer Microbicides
    Antimicrobial Agents and Chemotherapy, vol. 50, no. 9, pp. 3081–3089, 2006
  13. AP-1-directed human T cell leukemia virus type 1 viral gene expression during monocytic differentiation
    Journal of Leukocyte Biology, vol. 80, no. 3, pp. 640–650, 2006
  14. Cholesterol-Depleting Statin Drugs Protect Postmitotically Differentiated Human Neurons against Ethanol- and Human Immunodeficiency Virus Type 1-Induced Oxidative Stress In Vitro
    Journal of Virology, vol. 81, no. 3, pp. 1492–1501, 2006
  15. CCAAT/enhancer-binding proteins modulate human T cell leukemia virus type 1 long terminal repeat activation
    Virology, vol. 348, no. 2, pp. 354–369, 2006
  16. In Vitro Preclinical Testing of Nonoxynol-9 as Potential Anti-Human Immunodeficiency Virus Microbicide: a Retrospective Analysis of Results from Five Laboratories
    Antimicrobial Agents and Chemotherapy, vol. 50, no. 2, pp. 713–723, 2006
  17. Human T cell leukemia virus type I Tax activates CD40 gene expression via the NF-kappa B pathway
    Virology, vol. 333, no. 1, pp. 145–158, 2005
  18. HTLV-1 Tax nucleocytoplasmic shuttling, interaction with the secretory pathway, extracellular signaling, and implications for neurologic disease
    Journal of Biomedical Science, vol. 12, no. 6, pp. 961–974, 2005
  19. Prolonged exposure to the candidate microbicide C31G differentially reduces cellular sensitivity to agent re-exposure
    Biomedecine & Pharmacotherapy, vol. 59, no. 8, pp. 460–468, 2005
  20. Toxicity, inflammation, and anti-human immunodeficiency virus type 1 activity following exposure to chemical moieties of C31G
    Biomedecine & Pharmacotherapy, vol. 59, no. 8, pp. 430–437, 2005
  21. Polybiguanides, particularly polyethylene hexamethylene biguanide, have activity against human immunodeficiency virus type 1
    Biomedecine & Pharmacotherapy, vol. 59, no. 8, pp. 438–445, 2005
  22. Biochemical Analysis of Human Milk Treated With Sodium Dodecyl Sulfate, an Alkyl Sulfate Microbicide That Inactivates Human Immunodeficiency Virus Type 1
    Journal of Human Lactation, vol. 22, no. 1, pp. 61–74, 2005
  23. Secretion of the Human T Cell Leukemia Virus Type I Transactivator Protein Tax
    Journal of Biological Chemistry, vol. 280, no. 17, pp. 17353–17362, 2005
  24. Retrovirology, vol. 2, no. 1, p. 28, 2005
  25. Comparative Safety Evaluation of the Candidate Vaginal Microbicide C31G
    Antimicrobial Agents and Chemotherapy, vol. 49, no. 4, pp. 1509–1520, 2005
  26. Novel Polysulfated Galactose-Derivatized Dendrimers as Binding Antagonists of Human Immunodeficiency Virus Type 1 Infection
    Antimicrobial Agents and Chemotherapy, vol. 48, no. 5, pp. 1614–1623, 2004
  27. Specific sequence configurations of HIV-1 LTR G/C box array result in altered recruitment of Sp isoforms and correlate with disease progression
    Journal of Neuroimmunology, vol. 157, no. 1-2, pp. 39–47, 2004
  28. Region-specific distribution of human immunodeficiency virus type 1 long terminal repeats containing specific configurations of CCAAT/enhancer-binding protein site II in brains derived from demented and nondemented patients
    Journal of NeuroVirology, vol. 10, no. 0, pp. 7–14, 2004
  29. Mouse Model of Cervicovaginal Toxicity and Inflammation for Preclinical Evaluation of Topical Vaginal Microbicides
    Antimicrobial Agents and Chemotherapy, vol. 48, no. 5, pp. 1837–1847, 2004
  30. Human T-cell leukemia virus type I Tax induces the expression of dendritic cell markers associated with maturation and activation
    Journal of Neurovirology, vol. 10, no. 6, pp. 358–371, 2004
  31. Differences in N-linked glycosylation between human surfactant protein-B variants of the C or T allele at the single-nucleotide polymorphism at position 1580: implications for disease
    Biochemical Journal, vol. 369, no. 1, p. 179, 2003
  32. Structural and Functional Evolution of Human Immunodeficiency Virus Type 1 Long Terminal Repeat CCAAT/Enhancer Binding Protein Sites and Their Use as Molecular Markers for Central Nervous System Disease Progression
    Journal of Neurovirology, vol. 9, no. 1, pp. 55–68, 2003
  33. Mediators of Central Nervous System Damage During the Progression of Human T-Cell Leukemia Type I-Associated Myelopathy/Tropical Spastic Paraparesis
    Journal of Neurovirology, vol. 9, no. 5, pp. 522–529, 2003
  34. HIV-1 Infection in a Small Animal Human Vaginal Xenograft Model
    JAIDS Journal of Acquired Immune Deficiency Syndromes, vol. 34, no. 5, pp. 454–460, 2003
  35. Identification of binding sites for members of the CCAAT/enhancer binding protein transcription factor family in the simian immunodeficiency virus long terminal repeat
    Biomedecine & Pharmacotherapy, vol. 57, no. 1, pp. 34–40, 2003
  36. HIV-1 Vpr binding to HIV-1 LTR C/EBP cis-acting elements and adjacent regions is sequence-specific
    Biomedecine & Pharmacotherapy, vol. 57, no. 1, pp. 41–48, 2003
  37. C/EBP- and Tat-mediated activation of the HIV-1 LTR in CD34+ hematopoietic progenitor cells
    Biomedecine & Pharmacotherapy, vol. 57, no. 1, pp. 49–56, 2003
  38. Human T cell leukemia virus type I-induced disease: pathways to cancer and neurodegeneration
    Virology, vol. 308, no. 1, pp. 1–12, 2003
  39. Characterization of a Nuclear Export Signal within the Human T Cell Leukemia Virus Type I Transactivator Protein Tax
    Journal of Biological Chemistry, vol. 278, no. 24, pp. 21814–21822, 2003
  40. Comparative In Vitro Sensitivities of Human Immune Cell Lines, Vaginal and Cervical Epithelial Cell Lines, and Primary Cells to Candidate Microbicides Nonoxynol 9, C31G, and Sodium Dodecyl Sulfate
    Antimicrobial Agents and Chemotherapy, vol. 46, no. 7, pp. 2292–2298, 2002
  41. Human T cell leukemia virus type I and neurologic disease: Events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance and neuroinflammation
    Journal of Cellular Physiology, vol. 190, no. 2, pp. 133–159, 2002
  42. Regulation of Human Immunodeficiency Virus Type 1 Gene Expression and Pathogenesis by CCAAT/Enhancer Binding Proteins in Cells of the Monocyte/Macrophage Lineage
    Journal of Neurovirology, vol. 8, no. 2, pp. 21–26, 2002
  43. HIV-1 LTR C/EBP binding site sequence configurations preferentially encountered in brain lead to enhanced C/EBP factor binding and increased LTR-specific activity
    Journal of NeuroVirology, vol. 7, no. 3, pp. 235–249, 2001
  44. Interaction between CCAAT/Enhancer Binding Protein and Cyclic AMP Response Element Binding Protein 1 Regulates Human Immunodeficiency Virus Type 1 Transcription in Cells of the Monocyte/Macrophage Lineage
    Journal of Virology, vol. 75, no. 4, pp. 1842–1856, 2001
  45. Sodium Dodecyl Sulfate and C31G as Microbicidal Alternatives to Nonoxynol 9: Comparative Sensitivity of Primary Human Vaginal Keratinocytes
    Antimicrobial Agents and Chemotherapy, vol. 44, no. 7, pp. 1954–1960, 2000
  46. Human T cell lymphotropic virus type I genomic expression and impact on intracellular signaling pathways during neurodegenerative disease and leukemia
    Frontiers in Bioscience, vol. 5, no. 1, p. d138, 2000
  47. Analysis of the HIV-1 LTR NF-?B-Proximal Sp Site III: Evidence for Cell Type-Specific Gene Regulation and Viral Replication
    Virology, vol. 274, no. 2, pp. 262–277, 2000
  48. Upstream Stimulatory Factor Family Binds to the Herpes Simplex Virus Type 1 Latency-Associated Transcript Promoter
    Virology, vol. 230, no. 2, pp. 381–391, 1997
  49. Characterization of a glial cell-specific DNA-protein complex formed with the human T cell lymphotropic virus type I (HTLV-I) enhancer
    Journal of Neurovirology, vol. 1, no. 1, pp. 62–77, 1995
  50. Neuroglial-specific factors and the regulation of retrovirus transcription
    Advances in Neuroimmunology, vol. 4, no. 3, pp. 305–318, 1994
  51. Identification of a Second ATF/CREB-like Element in the Herpes Simplex Virus Type 1 (HSV-1) Latency-Associated Transcript (LAT) Promoter
    Virology, vol. 200, no. 1, pp. 220–235, 1994
  52. Transient expression of human immunodeficiency virus type 1 genome results in a nonproductive infection in human fetal dorsal root ganglia glial cells
    Virology, vol. 173, no. 2, pp. 715–722, 1989
  53. Human immunodeficiency virus infection of the developing human nervous system
    Virology, vol. 159, no. 2, pp. 440–445, 1987
  54. Varicella-zoster virus infection of human sensory neurons
    Virology, vol. 152, no. 2, pp. 384–399, 1986
  55. Herpes Simplex Virus Latency in Isolated Human Neurons
    Proceedings of the National Academy of Sciences, vol. 81, no. 19, pp. 6217–6221, 1984
  56. Herpes simplex virus latency and reactivation in isolated rat sensory neurons
    Virology, vol. 127, no. 1, pp. 159–167, 1983
  57. Maintenance of human cytomegalovirus genome in human diploid fibroblast cells
    Virology, vol. 130, no. 1, pp. 269–271, 1983
  58. Activation of herpes simplex virus (HSV) type 1 genome by temperature-sensitive mutants of HSV type 2
    Virology, vol. 116, no. 2, pp. 468–479, 1982
  59. Repression and Activation of the Genome of Herpes Simplex Viruses in Human Cells
    Proceedings of the National Academy of Sciences, vol. 78, no. 10, pp. 6522–6526, 1981