Paul Evans is Reader in endothelial physiology and Head of the Intracellular Signalling Group at the National Heart and Lung Institute, Imperial College London, London, UK. Dr Evans' group is interested in the signalling pathways that regulate proinflammatory activation and apoptosis in endothelial cells and how these processes are altered by shear stress, a mechanical force exerted on vessel walls by flowing blood. This subject is relevant to vascular injury and atherosclerosis which develop predominantly at branches and bends in the arterial tree that are exposed to disturbed blood flow. His group is also studying the signalling pathways that govern the systemic inflammatory response syndrome that can occur following coronary artery bypass grafting with cardiopulmonary bypass. Dr Evans gained his Ph.D. degree in transplantation immunology in 1996, and his studies in this field were recognized by the British Transplantation Society who awarded him the Medawar Prize in 2000. Dr Evans was awarded a Training Fellowship and then a Senior Fellowship by Kidney Research UK to study endothelial cell physiology before moving to Imperial College.
Biography Updated on 22 March 2011