Kazuhide Inoue (Kazu) works on the function of purinergic receptors in CNS, especially in microglia and astrocytes as well as neurons. Kazu’s group has found that P2X4 receptors in spinal microglia has important role in the expression of neuropathic pain that is often refractory to treatment with NSAIDs and opioids (Nature, 2003 & 2005), and the stimulation of P2Y6 receptors causes microglial phagocytosis (Nature, 2007). Kazu’s group also found that stimulation of P2Y1 in astrocytes evokes protecting neurons against oxidative stress. These data have a potential impact in the field of the neuron-glia interactions. Kazu received his Ph.D. from Kyushu University and works for the University. One of his dreams is to develop medicines for neuropathic pain through "Eco-Parma" that is a system for searching new drug candidates from the medicines which are already approved by governments to offer remedy to the patient immediately.
Biography Updated on 1 December 2008