Rameshwar K. Sharma
Rameshwar K. Sharma was born in Jammu-Tawi, India, in 1935. In 1958, he received his B.S. degree in pharmaceutical technology from the Birla Institute of Technology, Pilani, India. In 1960, he joined the University of Connecticut, Conn, USA for graduate work in medicinal chemistry and received his Ph.D. degree in 1963. Subsequently, after several postdoctoral positions, including at the Worcester Foundation for Experimental Biology, he joined the University of Tennessee Medical Center at Memphis, Tenn, USA where he rose to the rank of a Full Tenured Professor of biochemistry. During this period as an NIH Special Postdoctoral Fellow, he spent about two-year Sabbatical as a Visiting Professor at the McArdle Laboratory University of Wisconsin at Madison, Wis, USA and a two-year Sabbatical as an NIH Visiting Scientist, Bethesda, Md, USA. Subsequently, after Full Professorships at the Case Western University and Cleveland Clinic Foundation and at the University of Medicine and Dentistry at New Jersey, he is presently at the Slaus University, Pa, USA as a Distinguished Professor of biochemistry and molecular biology. During a period spanning four decades, his research team has been involved in the signal transduction research. With the discovery of the first membrane guanylate cyclase that was also a surface receptor of the hormone ANF, it established the field of membrane guanylate cyclase. Subsequently, with the discovery of ROS-GC membrane guanylate cyclase, the membrane guanylate cyclase family branched into another subfamily, ROS-GC, which is Ca2+-modulated, made up of two components, Ca2+-sensor protein and the transducer ROS-GC and is linked with phototransduction. With the discovery of the Ca2+-modulated ONE-GC, his research team has currently linked the membrane guanylate cyclase transduction field with the odorant transduction.
Biography Updated on 16 January 2011