Elise Chiffoleau performed her Ph.D. degree (1999-2002) in UMR Nantes-INSERM on the identification and characterization of new molecules involved in allograft tolerance. She performed a postdoctoral position (2002-2003) at the University of Pennsylvania, Phil, in the laboratory of Dr Laurence Turka. Her research was on the study of the mechanisms and molecular pathways of molecules (TRAF6, BclXL, Notch) involved in allograft or self-tolerance. She then obtained a permanent position at the Institut National de la Santé Et de la Recherche Médicale (INSERM) in Nantes, France in INSERM U643. Her research focuses now on the study of molecules involved in transplantation tolerance in rodents. She described, CLEC-1, a C-type lectin like receptor, as playing a role in antigen-presenting cell activation, and the subsequent T-helper cell differentiation. She also characterized a population of inhibited/inhibitory regulatory B cells able to transfer allograft tolerance.
Biography Updated on 28 April 2013