Ruediger Hehlmann
Personal Home Page
http://www.iacrlrd.org/.Ruediger Hehlmann
Articles in Scholarly Journals [Incomplete List]
- Imatinib combined with mitoxantrone/etoposide and cytarabine is an effective induction therapy for patients with chronic myeloid leukemia in myeloid blast crisis
Cancer, vol. 109, no. 8, pp. 1543–1549, 2007 - Zinc protoporphyrin, a useful parameter to address hyperferritinemia
Annals of Hematology, vol. 86, no. 5, pp. 363–368, 2007 - Chronic myeloid leukaemia
The Lancet, vol. 370, no. 9584, pp. 342–350, 2007 - Recurrent finding of the FIP1L1-PDGFRA fusion gene in eosinophilia-associated acute myeloid leukemia and lymphoblastic T-cell lymphoma
Leukemia, vol. 21, no. 6, Article ID 2404662, 5 pages, 2007 - Systemic mastocytosis simulating osseous metastatic disease
British Journal of Haematology, vol. 136, no. 1, pp. 1–1, 2007 - The soluble transferrin receptor in dysplastic erythropoiesis in myelodysplastic syndrome
European Journal of Haematology, vol. 79, no. 1, pp. 8–16, 2007 - DNA Microarray-Based Detection and Identification of Fungal Pathogens in Clinical Samples from Neutropenic Patients
Journal of Clinical Microbiology, vol. 45, no. 11, pp. 3743–3753, 2007 - Intestinal-type adenocarcinoma situated in the nasopharynx
Cytopathology, vol. 18, no. 1, pp. 59–63, 2007 - Low-dose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in FIP1L1-PDGFRA positive chronic eosinophilic leukemia
Blood, vol. 109, no. 11, pp. 4635–4640, 2007 - Centrosome aberrations after nilotinib and imatinib treatment in vitro are associated with mitotic spindle defects and genetic instability
British Journal of Haematology, vol. 138, no. 3, pp. 369–373, 2007 - Drug treatment is superior to allografting as first-line therapy in chronic myeloid leukemia
Blood, vol. 109, no. 11, pp. 4686–4692, 2007 - The soluble transferrin receptor reflects tumor load in chronic lymphocytic leukemia
Clinical Chemistry and Laboratory Medicine, vol. 45, no. 10, pp. 1313–1318, 2007 - Reliable Identification of Small Cell Lung Cancer in Cytological Specimens by Immunocytology
Onkologie, vol. 30, no. 6, pp. 311–315, 2007 - Characterization of three new imatinib-responsive fusion genes in chronic myeloproliferative disorders generated by disruption of the platelet-derived growth factor receptor gene
Haematologica, vol. 92, no. 2, pp. 163–169, 2007 - Dynamics of cytogenetic aberrations in Philadelphia chromosome positive and negative hematopoiesis during dasatinib therapy of chronic myeloid leukemia patients after imatinib failure
Haematologica, vol. 92, no. 6, pp. 834–837, 2007 - An international study to standardize the detection and quantitation of BCR-ABL transcripts from stabilized peripheral blood preparations by quantitative RT-PCR
Haematologica, vol. 92, no. 7, pp. 970–973, 2007 - Leukocytoclastic Vasculitis and Acute Renal Failure after Influenza Vaccination in an Elderly Patient with Myelodysplastic Syndrome
Onkologie, vol. 29, no. 10, pp. 470–472, 2006 - Klinische Forschung im „European LeukemiaNet”
DMW - Deutsche Medizinische Wochenschrift, vol. 131, no. 43, pp. 2423–2426, 2006 - Diagnosis and Therapy of Polycythemia Vera
Seminars in Thrombosis and Hemostasis, vol. 32, no. 3, pp. 267–275, 2006 - Cytogenetic response to prior treatment with interferon-a is predictive for survival after allogeneic hematopoietic stem cell transplantation in chronic myeloid leukemia
Leukemia, vol. 20, no. 3, Article ID 2404100, 7 pages, 2006 - Gene expression profiling of CD34+ cells identifies a molecular signature of chronic myeloid leukemia blast crisis
Leukemia, vol. 20, no. 6, Article ID 2404227, 6 pages, 2006 - Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patients
Leukemia, vol. 20, no. 8, Article ID 2404270, 7 pages, 2006 - Chronische myeloische Leukämie mit Management-Empfehlungen des European LeukemiaNet
Der Onkologe, vol. 12, no. 10, pp. 1012–1021, 2006 - Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and aCDK5RAP2-PDGFRA fusion gene
Genes, Chromosomes and Cancer, vol. 45, no. 10, pp. 950–956, 2006 - Klinische Forschung im Kompetenznetz „Akute und chronische Leukämien“
Medizinische Klinik, vol. 101, no. 5, pp. 414–420, 2006 - Response and resistance in 300 patients with BCR-ABL-positive leukemias treated with imatinib in a single center
Cancer, vol. 103, no. 8, pp. 1659–1669, 2005 - Chronic myeloid leukemia: a model for oncology
Annals of Hematology, vol. 84, no. 8, pp. 487–497, 2005 - Treatment concepts of acute promyelocytic leukemia
Critical Reviews in Oncology/Hematology, vol. 56, no. 2, pp. 261–274, 2005 - BBR 3438, a novel 9-aza-anthrapyrazole, in patients with advanced gastric cancer: A phase II study group trial of the central European Society of Anticancer-Drug Research (CESAR)
Investigational New Drugs, vol. 23, no. 4, pp. 363–368, 2005 - Induction of centrosome and chromosome aberrations by imatinib in vitro
Leukemia, vol. 19, no. 9, Article ID 2403861, 5 pages, 2005 - The t(8;17)(p11;q23) in the 8p11 myeloproliferative syndrome fuses MYO18A to FGFR1
Leukemia, vol. 19, no. 6, Article ID 2403712, 4 pages, 2005 - Gender aspects in chronic myeloid leukemia: long-term results from randomized studies
Leukemia, vol. 19, no. 6, Article ID 2403756, 5 pages, 2005 - Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability
Leukemia, vol. 19, no. 7, Article ID 2403779, 5 pages, 2005 - Peritoneal haematopoiesis in acute panmyelosis with myelofibrosis
British Journal of Haematology, vol. 130, no. 1, pp. 1–1, 2005 - Irinotecan and capecitabine as second-line treatment after failure for first-line infusional 24-h 5-fluorouracil/folinic acid in advanced colorectal cancer: a phase II study
Anti-Cancer Drugs, vol. 16, no. 1, pp. 39–45, 2005 - Pegylated liposomal doxorubicin and mitomycin C in combination with infusional 5-fluorouracil and sodium folinic acid in the treatment of advanced gastric cancer: results of a phase II trial
Anti-Cancer Drugs, vol. 16, no. 4, pp. 435–440, 2005 - Soluble transferrin receptor and zinc protoporphyrin - competitors or efficient partners?
European Journal of Haematology, vol. 75, no. 4, pp. 309–317, 2005 - Recurrent chemotherapy-induced tumor lysis syndrome (TLS) with renal failure in a patient with chronic lymphocytic leukemia - successful treatment and prevention of TLS with low-dose rasburicase
European Journal of Haematology, vol. 75, no. 6, pp. 518–521, 2005 - Comprehensive Analysis of Human Endogenous Retrovirus Transcriptional Activity in Human Tissues with a Retrovirus-Specific Microarray
Journal of Virology, vol. 79, no. 1, pp. 341–352, 2005 - Human Endogenous Retrovirus Expression Profiles in Samples from Brains of Patients with Schizophrenia and Bipolar Disorders
Journal of Virology, vol. 79, no. 17, pp. 10890–10901, 2005 - IgA nephropathy and hodgkins disease: A rare coincidence. Case report and literature review
American Journal of Kidney Diseases, vol. 45, no. 1, pp. e16–e19, 2005 - Phase I Trial of Capecitabine and Weekly Irinotecan in Combination With Radiotherapy for Neoadjuvant Therapy of Rectal Cancer
Journal of Clinical Oncology, vol. 23, no. 7, pp. 1350–1357, 2005 - Impact of Chemoradiotherapy-Induced Anemia on Survival in Uniformly Staged Patients with Locally Advanced Squamous Cell Carcinoma of the Esophagus
Onkologie, vol. 27, no. 5, pp. 462–466, 2004 - Fatal cerebral involvement in systemic aspergillosis: a rare complication of steroid-treated autoimmune bicytopenia
European Journal of Haematology, vol. 72, no. 5, pp. 375–376, 2004 - Detection of Aspergillus DNA by a nested PCR assay is superior to blood culture in an experimental murine model of invasive aspergillosis
Journal of Medical Microbiology, vol. 53, no. 8, pp. 803–806, 2004 - Standardization of Preanalytical Factors for Minimal Residual Disease Analysis in Chronic Myelogenous Leukemia
Acta Haematologica, vol. 112, no. 1-2, pp. 30–33, 2004 - Prospective clinical evaluation of a LightCyclerTM-mediated polymerase chain reaction assay, a nested-PCR assay and a galactomannan enzyme-linked immunosorbent assay for detection of invasive aspergillosis in neutropenic cancer patients and haematological stem cell transplant recipients
British Journal of Haematology, vol. 125, no. 2, pp. 196–202, 2004 - Current Molecular Diagnostic Approaches to Systemic Infections with Aspergillus Species in Patients with Hematological Malignancies
Leukemia & Lymphoma, vol. 45, no. 3, pp. 463–468, 2004 - Therapie der chronischen myeloischen Leukämie 2004
DMW - Deutsche Medizinische Wochenschrift, vol. 129, no. 40, pp. 2122–2127, 2004 - Das Kompetenznetzwerk „Akute und chronische Leukämien”
DMW - Deutsche Medizinische Wochenschrift, vol. 129, no. 49, pp. 2660–2665, 2004 - Capecitabine in combination with mitomycin C in patients with gastrointestinal cancer: results of an extended multicentre phase-I trial
British Journal of Cancer, Article ID 6602025, 2004 - Imatinib?Neuartige, molekulare Therapiem?glichkeit bei chronischer myeloischer Leuk?mie
Der Internist, vol. 45, no. 1, pp. 102–103, 2004 - Clonal aberrations in Philadelphia chromosome negative hematopoiesis in patients with chronic myeloid leukemia treated with imatinib or interferon alpha
Leukemia, vol. 19, no. 3, Article ID 2403607, 3 pages, 2004 - The German competence network ‘Acute and chronic leukemias’
Leukemia, vol. 18, no. 4, Article ID 2403317, 4 pages, 2004 - Treatment intensity significantly influencing fibrosis in bone marrow independently of the cytogenetic response: meta-analysis of the long-term results from two prospective controlled trials on chronic myeloid leukemia
Leukemia, vol. 18, no. 9, Article ID 2403451, 7 pages, 2004 - Pegylated liposomal doxorubicin in combination with mitomycin C, infusional 5-fluorouracil and sodium folinic acid. A phase-I-study in patients with upper gastrointestinal cancer
British Journal of Cancer, vol. 90, no. 10, Article ID 6601786, 4 pages, 2004 - Klinische Forschung im Kompetenznetz ?Akute und chronische Leuk?mien?
Der Internist, vol. 45, no. 4, pp. 384–392, 2004 - Management of infections in critically ill neutropenic cancer patients
Journal of Critical Care, vol. 19, no. 3, pp. 165–173, 2004 - Two potential mechanisms of oxaliplatin-induced haemolytic anaemia in a single patient
Cancer Chemotherapy and Pharmacology, vol. 53, no. 3, pp. 276–278, 2004 - Spontaneous remission in adult acute myeloid leukemia in association with systemic bacterial infection?case report and review of the literature
Annals of Hematology, vol. 83, no. 3, pp. 189–194, 2004 - Imatinib and beyond?the new CML study IV
Annals of Hematology, vol. 83, no. 4, pp. 258–264, 2004 - Chronische myeloproliferative Erkrankungen
Der Internist, vol. 44, no. 8, pp. 1011–1030, 2003 - Prognosis and prognostic factors for patients with chronic myeloid leukemia: Nontransplant therapy
Seminars in Hematology, vol. 40, no. 1, pp. 4–12, 2003 - Multilobated nuclei in Waldenstrom' macroglobulinaemia
European Journal of Haematology, vol. 71, no. 4, pp. 307–310, 2003 - Assessment of retroviral activity using a universal retrovirus chip
Journal of Virological Methods, vol. 112, no. 1-2, pp. 79–91, 2003 - Randomized comparison of interferon a and hydroxyurea with hydroxyurea monotherapy in chronic myeloid leukemia (CML-study II): prolongation of survival by the combination of interferon a and hydroxyurea
Leukemia, vol. 17, no. 8, Article ID 2403006, 8 pages, 2003 - Molecular monitoring of response to imatinib (Glivec®) in CML patients pretreated with interferon alpha. Low levels of residual disease are associated with continuous remission
Leukemia, vol. 17, no. 9, Article ID 2403033, 7 pages, 2003 - Instability of chromosome structure in cancer cells increases exponentially with degrees of aneuploidy
Cancer Genetics and Cytogenetics, vol. 143, no. 1, pp. 59–72, 2003 - Occurrence of additional chromosome aberrations in chronic myeloid leukemia patients treated with imatinib mesylate
Leukemia, vol. 17, no. 2, Article ID 2402813, 2 pages, 2003 - Prognosis and prognostic factors for patients with chronic myeloid leukemia: Nontransplant therapy
Seminars in Hematology, vol. 40, no. 1, pp. 4–12, 2003 - Current CML therapy: progress and dilemma
Leukemia, vol. 17, no. 6, Article ID 2402951, 2 pages, 2003 - Pseudomembranous tracheobronchial aspergillosis: a rare manifestation of invasive aspergillosis in a non-neutropenic patient with Hodgkin's disease. Fallbericht. Pseudomembranose tracheobronchiale Aspergillose: Seltene Manifestation einer Aspergillus-Infektion bei einer nicht-neutropenischen Patientin mit Morbus Hodgkin
Mycoses, vol. 46, no. 1-2, pp. 51–55, 2003 - Dynamics of BCR-ABL mRNA expression in first-line therapy of chronic myelogenous leukemia patients with imatinib or interferon a/ara-C
Leukemia, vol. 17, no. 12, Article ID 2403157, 8 pages, 2003 - Chronic myeloid leukemia in the elderly: long-term results from randomized trials with interferon a
Leukemia, vol. 17, no. 9, Article ID 2403042, 6 pages, 2003 - Successful treatment of hyperuricemia with low doses of recombinant urate oxidase in four patients with hematologic malignancy and tumor lysis syndrome
Leukemia, vol. 17, no. 12, Article ID 2403161, 2 pages, 2003 - Marrow fibrosis, indicator of therapy failure in chronic myeloid leukemia – prospective long-term results from a randomized-controlled trial
Leukemia, vol. 17, no. 12, Article ID 2403172, 9 pages, 2003 - Telomere length in peripheral blood granulocytes reflects response to treatment with imatinib in patients with chronic myeloid leukemia
Blood, vol. 101, no. 1, pp. 375–375, 2003 - Development of a LightCycler PCR Assay for Detection and Quantification of Aspergillus fumigatus DNA in Clinical Samples from Neutropenic Patients
Journal of Clinical Microbiology, vol. 41, no. 5, pp. 1811–1818, 2003 - Treatment of a Patient with Advanced Esophageal Cancer with a Combination of Mitomycin C and Capecitabine: Activation of the Thymidine Phosphorylase as Active Principle?
Onkologie, vol. 26, no. 2, pp. 161–164, 2003 - High-Dose 5-Fluorouracil / Folinic Acid in Combination with Three-Weekly Mitomycin C in the Treatment of Advanced Gastric Cancer. A Phase II Study
Onkologie, vol. 25, no. 3, pp. 255–260, 2002 - Specific aneusomies in Chinese hamster cells at different stages of neoplastic transformation, initiated by nitrosomethylurea
Proceedings of the National Academy of Sciences, vol. 99, no. 10, pp. 6778–6783, 2002 - Interferon-alpha , but not the ABL-kinase inhibitor imatinib (STI571), induces expression of myeloblastin and a specific T-cell response in chronic myeloid leukemia
Blood, vol. 101, no. 1, pp. 259–264, 2002 - Adding weekly irinotecan to high-dose 5-fluorouracil and folinic acid (HD-5-FU/FA) after failure for first-line HD-5-FU/FA in advanced colorectal cancer???a phase II study
Anti-Cancer Drugs, vol. 13, no. 10, pp. 999–1004, 2002 - Clinical evaluation of a polymerase chain reaction assay to detect Aspergillus species in bronchoalveolar lavage samples of neutropenic patients
British Journal of Haematology, vol. 116, no. 4, pp. 803–811, 2002 - Early reduction of BCR-ABL mRNA transcript levels predicts cytogenetic response in chronic phase CML patients treated with imatinib after failure of interferon a
Leukemia, vol. 16, no. 9, Article ID 2402680, 4 pages, 2002 - Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy
Leukemia, vol. 16, no. 11, pp. 2190–2196, 2002 - Alveolar rhabdomyosarcoma with bone marrow infiltration mimicking haematological neoplasia
British Journal of Haematology, vol. 119, no. 3, pp. 583–583, 2002 - Safety and efficacy of STI-571 (imatinib mesylate) in patients with bcr/abl-positive chronic myelogenous leukemia (CML) after autologous peripheral blood stem cell transplantation (PBSCT)
Leukemia, vol. 16, no. 7, pp. 1220–1228, 2002 - Echokardiographischer Nachweis von Trikuspidalklappen-Vegetationen und rechtskardialen Raumforderungen bei einem Patienten mit akuter myeloischer Leukämie
Ultraschall in der Medizin, vol. 23, no. 5, pp. 341–344, 2002 - Diagnostik und Therapie der chronischen myeloischen Leukämie
Der Onkologe, vol. 8, no. 7, pp. 693–707, 2002 - Aktuelle Therapiekonzepte bei chronischer myeloischer Leukämie
Der Internist, vol. 43, no. 10, pp. 1228–1244, 2002 - Gangrene of the toes in a patient with chronic myelogenous leukemia after long-term hydroxyurea therapy
Annals of Hematology, vol. 81, no. 8, pp. 467–469, 2002 - Predominantly BCR-ABL negative myeloid precursors in interferon-α treated chronic myelogenous leukemia: a follow-up study of peripheral blood colony-forming cells with fluorescence in situ hybridization
Annals of Hematology, vol. 80, no. 1, pp. 9–16, 2001 - Functional Activity of HERV-K-T47D-Related Long Terminal Repeats
Virology, vol. 283, no. 2, pp. 262–272, 2001 - Therapie der Polycythaemia vera
DMW - Deutsche Medizinische Wochenschrift, vol. 126, no. 14, pp. 415–415, 2001 - Proliferating status of peripheral blood progenitor cells from patients with BCR/ABL-positive chronic myelogenous leukemia
Leukemia, vol. 15, no. 1, pp. 62–68, 2001 - bcl-2 expression in non-Hodgkin's lymphomas is not associated with bcl-2 gene rearrangements
British Journal of Haematology, vol. 113, no. 2, pp. 383–390, 2001 - Current therapeutic concept of acute promyelocytic leukaemia
DMW - Deutsche Medizinische Wochenschrift, vol. 126, no. 39, pp. 1073–1079, 2001 - Detection of [ITAL]Aspergillus[/ITAL] Species in Blood and Bronchoalveolar Lavage Samples from Immunocompromised Patients by Means of 2-Step Polymerase Chain Reaction: Clinical Results
Clinical Infectious Diseases, vol. 33, no. 4, pp. 428–435, 2001 - Polyzythämia vera - Aktueller Stand der Therapie
DMW - Deutsche Medizinische Wochenschrift, vol. 126, no. 19, pp. 575–575, 2001 - Origin of multidrug resistance in cells with and without multidrug resistance genes: Chromosome reassortments catalyzed by aneuploidy
Proceedings of the National Academy of Sciences, vol. 98, no. 20, pp. 11283–11288, 2001 - Expression of nuclear transcription factor interferon consensus sequence binding protein in chronic myeloid leukemia correlates with pretreatment risk features and cytogenetic response to interferon-alpha
Blood, vol. 97, no. 11, pp. 3648–3650, 2001 - Die Bedeutung der Vernetzung für die klinische Forschung der Zukunft
Onkologie, vol. 24, no. 4, pp. 380–384, 2001 - Phase II Study of a Weekly 24-Hour Infusion with 5-Fluorouracil and Simultaneous Sodium – Folinic Acid in the First-Line Treatment of Metastatic Colorectal Cancer
Onkologie, vol. 24, no. 5, pp. 457–462, 2001 - ABL-BCR expression does not correlate with deletions on the derivative chromosome 9 or survival in chronic myeloid leukemia
Blood, vol. 98, no. 9, pp. 2879–2880, 2001 - AraC-based pharmacotherapy of chronic myeloid leukaemia
Expert Opinion on Pharmacotherapy, vol. 2, no. 7, pp. 1129–1135, 2001 - Selektive Hemmung von Tyrosinkinasen als neues therapeutisches Prinzip in der Onkologie
Onkologie, vol. 24, no. Suppl. 5, pp. 65–71, 2001 - Chronic myeloid leukemia and interferon-alpha : a study of complete cytogenetic responders
Blood, vol. 98, no. 10, pp. 3074–3081, 2001 - Systemic Infections with Aspergillus Species in Patients with Hematological Malignancies: Current Serological and Molecular Diagnostic Approaches
Onkologie, vol. 24, no. 6, pp. 531–536, 2001 - Reduced risk for chronic myelogenous leukemia in individuals with the cytochrome P-450 gene polymorphism CYP1A1*2A
Blood, vol. 98, no. 13, pp. 3874–3875, 2001 - Combination of Bolus 5-Fluorouracil, Folinic Acid and Mitomycin C in Advanced Gastric Cancer: Results of a Phase II Trial
Onkologie, vol. 23, no. 5, pp. 444–447, 2000 - Systemic Infections with Candida sp. and Aspergillus sp. in Immunocompromised Patients with Hematological Malignancies: Current Serological and Molecular Diagnostic Methods
Chemotherapy, vol. 46, no. 3, pp. 219–228, 2000 - Rapid Identification of All Known Retroviral Reverse Transcriptase Sequences with a Novel Versatile Detection Assay
AIDS Research and Human Retroviruses, vol. 16, no. 8, pp. 721–729, 2000 - Hydroxyurea versus busulphan for chronic myeloid leukaemia: an individual patient data meta-analysis of three randomized trials
British Journal of Haematology, vol. 110, no. 3, pp. 573–576, 2000 - HERV-IP-T47D, a Novel Type C-Related Human Endogenous Retroviral Sequence Derived from T47D Particles
AIDS Research and Human Retroviruses, vol. 16, no. 5, pp. 471–480, 2000 - Double induction strategy including high dose cytarabine in combination with all-trans retinoic acid: effects in patients with newly diagnosed acute promyelocytic leukemia
Leukemia, vol. 14, no. 8, pp. 1362–1370, 2000 - Frequent polymorphism in BCR exon b2 identified in BCR-ABL positive and negative individuals using fluorescent hybridization probes
Leukemia, vol. 14, no. 11, pp. 2006–2010, 2000 - Polyzythämia vera - Aktueller Stand der Therapie -
DMW - Deutsche Medizinische Wochenschrift, vol. 125, no. 41, pp. 1243–1247, 2000 - Detection and quantification of residual disease in chronic myelogenous leukemia
Leukemia, vol. 14, no. 6, pp. 998–1005, 2000 - Interferon α in the treatment of polycythemia vera
Annals of Hematology, vol. 79, no. 3, pp. 103–109, 2000 - HERV-K-T47D-Related Long Terminal Repeats Mediate Polyadenylation of Cellular Transcripts
Genomics, vol. 66, no. 1, pp. 98–103, 2000 - Current trends in the management of chronic myelogenous leukemia
Annals of Hematology, vol. 79, no. 7, pp. 345–354, 2000 - CD14+ peripheral blood mononuclear cells from chronic myeloid leukemia and normal donors are inhibitory to short- and long-term cultured colony-forming cells
Leukemia Research, vol. 24, no. 3, pp. 217–231, 2000 - Aneuploidy Precedes and Segregates with Chemical Carcinogenesis
Cancer Genetics and Cytogenetics, vol. 119, no. 2, pp. 83–93, 2000 - Comparative research in leukemia and related diseases. An introduction to a scientific approach
Leukemia, vol. 13, Article ID 2401289, 1999