Oreste Gualillo obtained his Ph.D. degree in pharmacology at the Department of Experimental Pharmacology of the University Federico II, Naples (Italy), after his graduation in pharmaceutical chemistry. He received training in molecular endocrinology under the mentoring of Professor Paul A. Kelly at the Necker School of Medicine, INSERM U344, Paris. In 1998, he moved to the Laboratory of Molecular Endocrinology of the University of Santiago de Compostela, Spain, where he worked as a Marie Curie Postdoctoral Research Fellow under the guidance of Professors Carlos Dieguez and Felipe Casanueva; in 2001, he set up his own research group at the Santiago University Clinical Hospital. He is currently an A Level Stable Researcher of the Carlos III Health Institute of the Spanish Ministry of Health at SERGAS (Servizo Galego de Saude), heading the Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases (NEIRID) group at the Santiago University Clinical Hospital. He has worked on the role of prolactin in immunity and inflammation and the intracellular transmission of the prolactin signal and on the regulation of leptin and ghrelin under various pathophysiological conditions and the intracellular transmission of the leptin signal. Since 2001, his research is focussed on the unravelling of the molecular signaling triggered by adipokines and on the pathways through which adipokines are involved in rheumatic diseases and in the inflammatory response of chondrocytes. Over the past years, his group has contributed to multiple aspects of research on the roles of adipokines in inflammation in rheumatic disorders and to define the molecular basis of ghrelin action in chondrocytes and other systems. He is on the editorial boards of several journals and serves as a referee for several grant-giving bodies and journals.
Biography Updated on 18 October 2012