Christian Hölscher
University of Ulster, United Kingdom
Christian Hölscher is specialized in neuroscience. His main research techniques include electrophysiological and behavioral studies, recording from single cells in vivo and recording field potentials in brain regions in behaving animals. The encoding, processing, and storage of information by the CNS is one of his points of interest. Since October 2006, he is a Senior Lectureship (Associate Professor) at the School of Biomedical Sciences, University of Ulster, Northern Ireland. In June 2004, he was Lectureship (Assistant Professor) at the School of Biomedical Sciences, University of Ulster, Northern Ireland. From 2001 to 2004, he was an Assistant Professor at the Department of Cognitive Neuroscience, University of Tübingen. In 1999-2000, he had MRC Research Fellowship in neuroscience, Department of Experimental Psychololgy, University of Oxford. In 1997–1999, he was temporary Lectureship in physiology, Department of Physiology, University College, Dublin, Ireland. In 1995–1997, he had European Human Capital and Mobility fellowship, Department of Pharmacololgy and Therapeutics, Trinity College, Dublin, Ireland. Hölscher received the Habilitation at the Faculty of Biology (Elected Member of the Faculty, which permits to independently work and teach) in 2002; Ph.D. degree in neuroscience at Biology Department, the Open University, UK, in 1991–1994; M.S. degree in neurobiology from Deptartment of Neuropharmacology, University of Tübingen, Germany, in 1990-1991. From 1984 to 1989, Hölscher studied biology and biochemistry from University of Kiel, Germany; in 1983 the Abitur (leaving certificate) in Wilhelmshaven; and in 1979-1980, Exchange Student of High School diploma in Long Beach, Mississippi, USA.
Biography Updated on 5 August 2007
Personal Home Page
homepage.mac.com/christian_holscher/
Articles in Scholarly Journals [Incomplete List]
- Soluble beta-amyloid[25–35] reversibly impairs hippocampal synaptic plasticity and spatial learning
European Journal of Pharmacology, vol. 561, no. 1-3, pp. 85–90, 2007 - Aß42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology
EMBO reports, vol. 7, no. 9, Article ID 7400784, 6 pages, 2006 - Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid (25â??35) are dependent on stimulation-protocol and genetic background
Experimental Brain Research, vol. 179, no. 4, pp. 621–630, 2006 - Inactivation of the rat dorsal striatum impairs performance in spatial tasks and alters hippocampal theta in the freely moving rat
Behavioural Brain Research, vol. 164, no. 1, pp. 73–82, 2005 - Lack of the metabotropic glutamate receptor subtype 7 selectively modulates Theta rhythm and working memory
Learning & Memory, vol. 12, no. 5, pp. 450–455, 2005 - Rats are able to navigate in virtual environments
Journal of Experimental Biology, vol. 208, no. 3, pp. 561–569, 2005 - Lack of the metabotropic glutamate receptor subtype 7 selectively impairs short-term working memory but not long-term memory
Behavioural Brain Research, vol. 154, no. 2, pp. 473–481, 2004 - Learned association of allocentric and egocentric information in the hippocampus
Experimental Brain Research, vol. 158, no. 2, 2004 - Perirhinal cortex neuronal activity related to long-term familiarity memory in the macaque
European Journal of Neuroscience, vol. 18, no. 7, pp. 2037–2046, 2003 - Reward modulates neuronal activity in the hippocampus of the rat
Behavioural Brain Research, vol. 142, no. 1-2, pp. 181–191, 2003 - Metabotropic glutamate receptors control gating of spike transmission in the hippocampus area CA1
Pharmacology Biochemistry and Behavior, vol. 73, no. 2, pp. 307–316, 2002 - Perirhinal Cortex Neuronal Activity is Actively Related to
Working Memory in the Macaque
Neural Plasticity, vol. 9, no. 1, pp. 41–51, 2002 - Different strains of rats show different sensitivity to block of long-term potentiation by nitric oxide synthase inhibitors
European Journal of Pharmacology, vol. 457, no. 2-3, pp. 99–106, 2002 - Stress impairs performance in spatial water maze learning tasks
Behavioural Brain Research, vol. 100, no. 1-2, pp. 225–235, 1999 - Synaptic plasticity and learning and memory: LTP and beyond
Journal of Neuroscience Research, vol. 58, no. 1, pp. 62–75, 1999 - Metabotropic glutamate receptor activation and blockade: their role in long-term potentiation, learning and neurotoxicity
Neuroscience & Biobehavioral Reviews, vol. 23, no. 3, pp. 399–410, 1999 - Retraction
European Journal of Neuroscience, vol. 11, no. 7, pp. 2596–2596, 1999 - Nitric oxide is required for expression of LTP that is induced by stimulation phase-locked with theta rhythm
European Journal of Neuroscience, vol. 11, no. 1, pp. 335–343, 1999 - Consciousness in mind: a correlate for ACh?
Trends in Neurosciences, vol. 22, no. 12, pp. 541–542, 1999 - Possible Causes of Alzheimer's Disease: Amyloid Fragments, Free Radicals, and Calcium Homeostasis
Neurobiology of Disease, vol. 5, no. 3, pp. 129–141, 1998 - Glucocorticoid receptor and protein/RNA synthesis-dependent mechanisms underlie the control of synaptic plasticity by stress
Proceedings of the National Academy of Sciences, vol. 95, no. 6, pp. 3204–3208, 1998 - HFS-induced long-term potentiation and LFS-induced depotentiation in area CA1 of the hippocampus are not good models for learning
Psychopharmacology, vol. 130, no. 2, pp. 174–182, 1997 - Block of theta-burst-induced long-term potentiation by (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid: further evidence against long-term potentiation as a model for learning
Neuroscience, vol. 81, no. 1, pp. 17–22, 1997 - Activation of group-II metabotropic glutamate receptors blocks induction of long-term potentiation and depotentiation in area CA1 of the rat in vivo
European Journal of Pharmacology, vol. 322, no. 2-3, pp. 155–163, 1997 - Nitric oxide, the enigmatic neuronal messenger: its role in synaptic plasticity
Trends in Neurosciences, vol. 20, no. 7, pp. 298–303, 1997 - Journal of Psycholinguistic Research, vol. 26, no. 4, pp. 425–448, 1997
- Long-term potentiation: A good model for learning and memory?
Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 21, no. 1, pp. 47–68, 1997 - -AP4 (-(+)-2-amino-4-phosphonobutyric acid) induced impairment of spatial learning in the rat is antagonized by MAP4 ((S)-2-amino-2methyl-4-phosphonobutanoic acid)
Behavioural Brain Research, vol. 81, no. 1-2, pp. 69–79, 1996 - 7-Nitro indazole, a selective neuronal nitric oxide synthase inhibitor in vivo, impairs spatial learning in the rat.
Learning & Memory, vol. 2, no. 6, pp. 267–278, 1996 - Training in the Morris water maze occludes the synergism between ACPD and arachidonic acid on glutamate release in synaptosomes prepared from rat hippocampus.
Learning & Memory, vol. 3, no. 4, pp. 296–304, 1996 - Prostaglandins play a role in memory consolidation in the chick
European Journal of Pharmacology, vol. 294, no. 1, pp. 253–259, 1995 - Inhibitors of Cyclooxygenases produce Amnesia for a Passive Avoidance Task in the Chick
European Journal of Neuroscience, vol. 7, no. 6, pp. 1360–1365, 1995 - Quinacrine Acts like an Acetylcholine Receptor Antagonist Rather Than like a Phospholipase A2 Inhibitor in a Passive Avoidance Task in the Chick
Neurobiology of Learning and Memory, vol. 63, no. 2, pp. 206–208, 1995 - Quinolinic acid lesion of the rat entorhinal cortex pars medialis produces selective amnesia in allocentric working memory (WM), but not in egocentric WM
Behavioural Brain Research, vol. 63, no. 2, pp. 187–194, 1994 - Inhibitors of phospholipase A2 produce amnesia for a passive avoidance task in the chick
Behavioral and Neural Biology, vol. 61, no. 3, pp. 225–232, 1994 - Inhibiting synthesis of the putative retrograde messenger nitric oxide results in amnesia in a passive avoidance task in the chick
Brain Research, vol. 619, no. 1-2, pp. 189–194, 1993 - An inhibitor of nitric oxide synthesis prevents memory formation in the chick
Neuroscience Letters, vol. 145, no. 2, pp. 165–167, 1992