Jack Leunissen
Jack Leunissen holds a Ph.D. in biochemistry from the University of Nijmegen (the Netherlands). From 1986, he created and managed the Bioinformatics and Genomics Section at the Dutch National Centre for Bioinformatics and Cheminformatics, CAOS/CAMM Center. In 2000, he was appointed a Senior Lecturer in Bioinformatics at the Centre for Molecular and Biomolecular Informatics (CMBI), Nijmegen University. In 2000, he also founded the Dutch bioinformatics company Dalicon B.V. (http://www.dalicon.com/). At the end of 2002, he moved to Wageningen University to be a Full Professor in bioinformatics and the Head of the Laboratory of Bioinformatics.
Biography Updated on 4 November 2008
Personal Home Page
http://www.bioinformatics.nl/~jackl/
Articles in Scholarly Journals [Incomplete List]
- Role of the Synthase Domain of Ags1p in Cell Wall -Glucan Biosynthesis in Fission Yeast
Journal of Biological Chemistry, vol. 282, no. 26, pp. 18969–18979, 2007 - A Protein Classification Benchmark collection for machine learning
Nucleic Acids Research, vol. 35, no. Database, pp. D232–D236, 2007 - Primer3Plus, an enhanced web interface to Primer3
Nucleic Acids Research, vol. 35, no. Web Server, pp. W71–W74, 2007 - BMC Bioinformatics, vol. 7, no. 1, p. 438, 2006
- BMC Bioinformatics, vol. 7, no. 1, p. 444, 2006
- TreeDomViewer: a tool for the visualization of phylogeny and protein domain structure
Nucleic Acids Research, vol. 34, no. Web Server, pp. W104–W109, 2006 - A text-mining analysis of the human phenome
European Journal of Human Genetics, vol. 14, no. 5, Article ID 5201585, 7 pages, 2006 - Evolution of web services in bioinformatics
Briefings in Bioinformatics, vol. 6, no. 2, pp. 178–188, 2005 - GeneSeeker: extraction and integration of human disease-related information from web-based genetic databases
Nucleic Acids Research, vol. 33, no. Web Server, pp. W758–W761, 2005 - Identification and expression of the first nonmammalian amyloid-beta precursor-like protein APLP2 in the amphibian Xenopus laevis
European Journal of Biochemistry, vol. 271, no. 10, pp. 1906–1912, 2004 - Satellite repeats in the functional centromere and pericentromeric heterochromatin of Medicago truncatula
Chromosoma, vol. 113, no. 6, pp. 276–283, 2004 - A new web-based data mining tool for the identification of candidate genes for human genetic disorders
European Journal of Human Genetics, vol. 11, no. 1, Article ID 5200918, 6 pages, 2003 - The human genome encodes 10 α-crystallin–related small heat shock proteins: HspB1–10
Cell Stress & Chaperones, vol. 8, no. 1, p. 53, 2003 - Chimera: construction of chimeric sequences for phylogenetic analysis
Bioinformatics, vol. 19, no. 2, pp. 303–304, 2003 - EXProt: a database for proteins with an experimentally verified function
Nucleic Acids Research, vol. 30, no. 1, pp. 50–51, 2002 - Hydrogenosomes: convergent adaptations of mitochondria to anaerobic environments
Zoology, vol. 104, no. 3-4, pp. 290–302, 2001 - Oreochromis mossambicus (tilapia) Corticotropin-Releasing Hormone: cDNA Sequence and Bioactivity
Journal of Neuroendocrinology, vol. 12, no. 2, pp. 177–186, 2000 - USAGE: a web-based approach towards the analysis of SAGE data
Bioinformatics, vol. 16, no. 10, pp. 899–905, 2000 - Distinct frequency-distributions of homopolymeric DNA tracts in different genomes
Nucleic Acids Research, vol. 26, no. 17, pp. 4056–4062, 1998 - Cloning and expression of two proopiomelanocortin mRNAs in the common carp (Cyprinus carpio L.)
Molecular and Cellular Endocrinology, vol. 143, no. 1-2, pp. 23–31, 1998 - Genealogy of the a-crystallin—small heat-shock protein superfamily
International Journal of Biological Macromolecules, vol. 22, no. 3-4, pp. 151–162, 1998 - Cloning and sequence analysis of a hypothalamic cDNA encoding a D1c dopamine receptor in tilapia
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol. 1308, no. 1, pp. 17–22, 1996 - Protein sequences indicate that turtles branched off from the amniote tree after mammals
Journal of Molecular Evolution, vol. 42, no. 5, pp. 580–586, 1996 - Molecular characterization of the human peroxisomal branchedchain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome
Proceedings of the National Academy of Sciences, vol. 93, no. 24, pp. 13748–13753, 1996 - The expanding small heat-shock protein family, and structure predictions of the conserved ??-crystallin domain?
Journal of Molecular Evolution, vol. 40, no. 3, pp. 238–248, 1995 - Molecular evolution of interleukin-3
Journal of Molecular Evolution, vol. 39, no. 3, pp. 255–267, 1994 - A molecular dynamics approach for the generation of complete protein structures from limited coordinate data
Proteins: Structure, Function, and Genetics, vol. 18, no. 2, pp. 174–185, 1994 - Journal of Chemical Information and Computer Sciences, vol. 33, no. 6, pp. 858–862, 1993
- Sequence analysis of the first intron of the bovine ?s-crystallin gene
Molecular Biology Reports, vol. 15, no. 2, pp. 93–94, 1991 - Light microscopical detection of leukocyte cell surface antigens with a one-nanometer gold probe
Histochemistry, vol. 95, no. 5, pp. 483–490, 1991 - Extreme differences in charge changes during protein evolution
Journal of Molecular Evolution, vol. 31, no. 1, pp. 33–39, 1990 - The ?-crystallin gene families: Sequence and evolutionary patterns
Journal of Molecular Evolution, vol. 27, no. 2, pp. 163–172, 1988 - Biogenesis of F71 and F72 fimbriae of uropathogenic Escherichia coli: influence of the FsoF and FstFG proteins and localization of the Fso/FstE protein
Molecular Microbiology, vol. 2, no. 1, pp. 73–80, 1988 - Analysis of a cDNA Clone Expressing a Human Autoimmune Antigen: Full-Length Sequence of the U2 Small Nuclear RNA-Associated B' '} Antigen
Proceedings of the National Academy of Sciences, vol. 84, no. 8, pp. 2421–2425, 1987 - The Lens Protein alpha A-crystallin of the Blind Mole Rat, Spalax ehrenbergi: Evolutionary Change and Functional Constraints
Proceedings of the National Academy of Sciences, vol. 84, no. 15, pp. 5320–5324, 1987 - Copper/Zinc superoxide dismutase: How likely is gene transfer from ponyfish toPhotobacterium leiognathi?
Journal of Molecular Evolution, vol. 23, no. 3, pp. 250–258, 1986 - Phylogenetic trees constructed from hydrophobicity values of protein sequences
Journal of Theoretical Biology, vol. 119, no. 2, pp. 189–196, 1986 - Periplasmic accumulation of truncated forms of outer-membrane PhoE protein of Escherichia coli K-12
Journal of Molecular Biology, vol. 189, no. 3, pp. 449–455, 1986 - Ultrastructural localization of a peroxisomal protein in rat liver using the specific antibody against the non-specific lipid transfer protein (sterol carrier protein 2)
Biochimica et Biophysica Acta (BBA) - Biomembranes, vol. 812, no. 2, pp. 387–392, 1985 - Interaction of alpha-crystallin with lens plasma membranes. Affinity for MP26
European Journal of Biochemistry, vol. 152, no. 3, pp. 721–728, 1985 - The localisation of phoE and ?-galactosidase antigens in wild type and phoE/lacZ hybrid
Cell Biology International Reports, vol. 8, no. 3, p. 187, 1984 - Ratites as oldest offshoot of avian stem—evidence from a-crystallin A sequences
Nature, vol. 311, no. 5983, Article ID 311257a0, 2 pages, 1984 - Internally elongated rodent ?-crystallin A chain: Resulting from incomplete RNA splicing?
Biochemical and Biophysical Research Communications, vol. 96, no. 2, pp. 648–655, 1980