Laura Gribaldo is Leader of the competence group Applied Molecular Biology at the Molecular Biology & Genomics Unit of the Institute for Health and Consumer Protection of the JRC, European Commission. She holds M.D. and Ph.D. degrees in microbiology and virology and she was working for ECVAM from1992 to 2009, as Key Area Leader in haematology and immunotoxicology. Since 2007, she was responsible for the coordination and leadership of the action Validation for Pharmaceuticals (Val Drug), covering the areas of systemic and reproductive toxicity. The main objective of the action was to validate new methodologies for risk assessment of pharmaceuticals according to the requirements in Directive 86/609/EEC on the protection of animals used for experimental and other scientific purposes. Several prospective validation studies have been carried out under her coordination, such as a study to evaluate a set of in vitro tests to detect immunosuppressant compounds. As cochair of the European Partnership for Alternative Approaches (EPAA) working group 5 on Validation and Acceptance, she participated in the Implementation of the Action programme and the preparation of the list of methods in the ECVAM pipeline to be supported by the partnership. She is a Member of the British Society of Toxicology and of the European Society of In Vitro Toxicology. Currently, she is involved in the coordination of validation studies in toxicogenomics and genetic testing, to determine the reproducibility and robustness of datasets, evaluate different cell models, and to engage with the chemical industry and EU regulators to highlight the application of toxicogenomics for risk assessment purposes.
Biography Updated on 14 March 2011