Louisa Braal Tabatabai
Louisa Braal Tabatabai received her B.A. degree in chemistry in 1962 from the University of California at Berkeley, Calif, USA. She earned her M.S. degree and Ph.D. degrees in 1966 and 1976 in food technology and biochemistry, respectively, from Iowa State University, Ames, Iowa, USA. Her studies for the Ph.D. degree were on the elucidation of the kinetic parameters of rabbit muscle phosphorylase kinase using natural substrates and synthetic peptide substrates. She joined the National Animal Disease Center, US Department of Agriculture, as a National Research Council Postdoctoral Fellow from 1977 to 1979. She was appointed as research chemist and worked as lead scientist for various projects from 1979 to 2011 when she retired from the USDA. In 1985, she was appointed as an Assistant professor/collaborator of biochemistry, as an associate professor/collaborator of biochemistry in 1990, and as a professor/collaborator of biochemistry in 1995 until present. Dr. Tabatabai served as a Professor-in-Charge of the Iowa State University Protein Core Facility from 1987 to 2006. Her research is focused on the role of bacterial proteins and enzymes in the pathogenesis of disease caused by Haemophilus parasuis (causative agent of Glässer’s disease of swine), Ornithobacterium rhinotracheale (causative agent of airsacculitis of avian species), and other pathogens such as Pasteurella haemolytica, Pasteurella multocida, Brucella abortus, Haemophilus parasuis, and Mycoplasma bovis. Areas of interest include protein chemistry, proteomics, 3-D modeling, and structure/function relationships of the bacterial proteins involved with host/pathogen interactions, including iron-regulated proteins, receptor proteins, colonization factors, and virulence proteins such as hemolysins and metalloproteases. The identified proteins/peptides are then further studied as targets for vaccine development and functional studies.
Biography Updated on 6 January 2013