Wuyuan Lu received his Ph.D. degree in protein biophysical chemistry from the Department of Chemistry, Purdue University, and was trained as a Postdoctoral Fellow of synthetic peptide chemistry at the Scripps Research Institute. After a brief tenure as a Senior Staff Scientist and a Group Leader in protein biochemistry at Gryphon Sciences, Inc., and as a Research Associate (then Assistant Professor) at the University of Chicago, Dr. Lu joined the Institute of Human Virology in July 2000, and was promoted to be an Associate Professor with tenure in June 2005. Dr. Lu’s major scientific expertise and research achievements lie in using chemical protein engineering approaches to elucidate the molecular basis for protein function. His current research interests center on applying the tools of contemporary synthetic peptide/protein chemistry and structural biology to tackle significant biomedical problems in cancer and infectious disease. His laboratory is currently focused on (1) elucidating the structure and function relationships for and mechanisms of action of human defensins in innate and adaptive immune responses; and (2) using combinatorial library screening and structure-based rational design to discover novel classes of antitumor and anti-HIV peptides for potential therapeutic use.
Biography Updated on 16 November 2008