Dr Helder Marçal has years of recognised research experience in tissue engineering technologies and regenerative medicine therapeutics. Dr marcal's research spans multidisciplinary fields of biomedical engineering, stem-cell therapeutics, expression proteomics, biomatrix engineering. His expertise utilises the salamander as a model for tissue repair and regeneration. In addition, he has identified a molecular mimicry mechanism involved in the immune-pathogenesis of reactive arthritis, psoriatic arthritis, uveitis and ankylosing spondylitis. These are associated with individuals that are HLA-B27 positive and how microorganisms trigger autoimmunity. Dr Marçal was a finalist for UNSWs inventor of the year. This technology opens the way for the development of the first peptide vaccine to inhibit the immunopathogenesis of diseases. His research has been highlighted in the Sydney Morning Herald, Discovery Channel, ABC Catalyst show and The Sunday Telegraph. He has established international collaborations involving these technologies in the field of regenerative and translational medicine and presented at numerous international conferences. Dr Marçal’s knowledge and skills span across different research that include tissue regeneration in space. This is a project that is investigating the impact of space travel especially, microgravity and its effect on human stem cells and liver regeneration. This is a new area of research called Bioastronautics and Dr Marçal is using the NASA designed bioreactor to analyze these impacts. This work has been covered by the Discover Chanel and has resulted in an international collaboration with NASA-AMES. He has been a visiting scientist at the Penguin Automated Research Centre (Canada), McGowan Institute for Regenerative Medicine (Pittsburgh), European Stem Cell Centre of Excellence (Portugal), and the Californian Institute for Regenerative Medicine (USA).
Biography Updated on 9 December 2013