Brian Cannon received his B.S. degree in physics from Auburn University, Auburn, Ala, USA. He obtained his M.S. degree and his Ph.D. degree in physics from Texas Tech University, Lubbock, Tex, USA. For his dissertation, he studied the role of membrane composition on the lateral organization of membrane components and its effect on the functioning of membrane-associated proteins using fluorescent spectroscopy, single ion channel recording, and fluorescence microscopy. As a Postdoctoral Researcher at the Institute of Cellular and Molecular Biology (ICMB), University of Texas, Austin, he developed single-molecule fluorescence methodologies for application in a range of biochemical systems, including the intramolecular dynamics of ribozymes from Tetrahymena thermophila and the hepatitis delta virus. He received the National Institutes of Health Ruth L. Kirschstein postdoctoral fellowship to sponsor his research on RNA-protein dynamics. Currently, he is a Research Associate at the ICMB. His research interests are the application of single-molecule fluorescence methodologies to study molecular interactions at the nanometer scale. The systems that he is currently studying include the quantitative detection of expanded alleles associated with Fragile X syndrome, protein recruitment in double-stranded DNA break repair mechanisms, and the interaction of peptides with Holliday junctions.
Biography Updated on 31 March 2013