J. Christopher Corton

Articles in Scholarly Journals [Incomplete List]

  1. Toward a Checklist for Exchange and Interpretation of Data from a Toxicology Study
    Toxicological Sciences, vol. 99, no. 1, pp. 26–34, 2007
  2. Toxicogenomic Study of Triazole Fungicides and Perfluoroalkyl Acids in Rat Livers Predicts Toxicity and Categorizes Chemicals Based on Mechanisms of Toxicity
    Toxicological Sciences, vol. 97, no. 2, pp. 595–613, 2007
  3. Activation of Peroxisome Proliferator-Activated Receptor Alpha Enhances Apoptosis in the Mouse Liver
    Toxicological Sciences, vol. 92, no. 2, pp. 368–377, 2006
  4. The role of tumor necrosis factor a and the peroxisome proliferator-activated receptor a in modulating the effects of fumonisin in mouse liver
    Toxicology, vol. 222, no. 3, pp. 165–174, 2006
  5. Role of PPAR? in mediating the effects of phthalates and metabolites in the liver
    Toxicology, vol. 207, no. 1, pp. 149–163, 2005
  6. Regulation of phase I and phase II steroid metabolism enzymes by PPAR? activators
    Toxicology, vol. 204, no. 2-3, pp. 109–121, 2004
  7. Role of the peroxisome proliferator-activated receptor ? (PPAR?) in responses to trichloroethylene and metabolites, trichloroacetate and dichloroacetate in mouse liver
    Toxicology, vol. 203, no. 1-3, pp. 83–98, 2004
  8. PPAR? activators down-regulate CYP2C7, a retinoic acid and testosterone hydroxylase
    Toxicology, vol. 203, no. 1-3, pp. 41–48, 2004
  9. Mimetics of Caloric Restriction Include Agonists of Lipid-activated Nuclear Receptors
    Journal of Biological Chemistry, vol. 279, no. 44, pp. 46204–46212, 2004
  10. The Transcriptional Response to a Peroxisome Proliferator-activated Receptor   Agonist Includes Increased Expression of Proteome Maintenance Genes
    Journal of Biological Chemistry, vol. 279, no. 50, pp. 52390–52398, 2004
  11. Decreased Longevity and Enhancement of Age-Dependent Lesions in Mice Lacking the Nuclear Receptor Peroxisome Proliferator-Activated Receptor ? (PPAR?)
    Toxicologic Pathology, vol. 32, no. 5, pp. 591–599, 2004
  12. GENE EXPRESSION PROFILING IN SPLEENS OF DEOXYNIVALENOL-EXPOSED MICE: IMMEDIATE EARLY GENES AS PRIMARY TARGETS
    Journal of Toxicology and Environmental Health Part A, vol. 67, no. 18, pp. 1423–1441, 2004
  13. Peroxisome Proliferator-Activated Receptors: Mediators of Phthalate Ester-Induced Effects in the Male Reproductive Tract?
    Toxicological Sciences, vol. 83, no. 1, pp. 4–17, 2004
  14. Constitutive Expression of Peroxisome Proliferator-Activated Receptor  -Regulated Genes in Dwarf Mice
    Molecular Pharmacology, vol. 67, no. 3, pp. 681–694, 2004
  15. Overlapping Transcriptional Programs Regulated by the Nuclear Receptors Peroxisome Proliferator-Activated Receptor  , Retinoid X Receptor, and Liver X Receptor in Mouse Liver
    Molecular Pharmacology, vol. 66, no. 6, pp. 1440–1452, 2004
  16. Opposing mechanisms of NADPH-cytochrome P450 oxidoreductase regulation by peroxisome proliferators
    Biochemical Pharmacology, vol. 65, no. 6, pp. 949–959, 2003
  17. Role of the peroxisome proliferator-activated receptor a in responses to diisononyl phthalate
    Toxicology, vol. 191, no. 2-3, pp. 211–225, 2003
  18. Delayed liver regeneration in peroxisome proliferator-activated receptor-a-null mice
    Hepatology, vol. 36, no. 3, pp. 544–554, 2002
  19. Fatty Acid Homeostasis and Induction of Lipid Regulatory Genes in Skeletal Muscles of Peroxisome Proliferator-activated Receptor (PPAR) alpha Knock-out Mice. EVIDENCE FOR COMPENSATORY REGULATION BY PPARdelta
    Journal of Biological Chemistry, vol. 277, no. 29, pp. 26089–26097, 2002
  20. Acute cadmium exposure induces stress-related gene expression in wild-type and metallothionein-I/II-null mice
    Free Radical Biology and Medicine, vol. 32, no. 6, pp. 525–535, 2002
  21. Effect of Peroxisome Proliferators on Leydig Cell Peripheral-Type Benzodiazepine Receptor Gene Expression, Hormone-Stimulated Cholesterol Transport, and Steroidogenesis: Role of the Peroxisome Proliferator-Activator Receptor  
    Endocrinology, vol. 143, no. 7, pp. 2571–2583, 2002
  22. Role of Thyroid Hormones in Hepatic Effects of Peroxisome Proliferators
    Toxicologic Pathology, vol. 29, no. 1, pp. 149–155, 2001
  23. Altered expression of the carboxylesterases ES-4 and ES-10 by peroxisome proliferator chemicals
    Toxicology, vol. 165, no. 2-3, pp. 109–119, 2001
  24. Hepatocellular proliferation in response to a peroxisome proliferator does not require TNFalpha signaling
    Carcinogenesis, vol. 22, no. 11, pp. 1843–1851, 2001
  25. Peroxisome Proliferator-Activated Receptor Alpha-Null Mice Lack Resistance to Acetaminophen Hepatotoxicity following Clofibrate Exposure
    Toxicological Sciences, vol. 57, no. 2, pp. 338–344, 2000
  26. Toward Construction of a Transcript Profile Database Predictive of Chemical Toxicity
    Toxicological Sciences, vol. 58, no. 2, pp. 217–219, 2000
  27. Apoptosis, mitosis and cyclophilin-40 expression in regressing peroxisome proliferator-induced adenomas
    Carcinogenesis, vol. 21, no. 4, pp. 647–652, 2000
  28. Central role of PPARa in the mechanism of action of hepatocarcinogenic peroxisome proliferators
    Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 448, no. 2, pp. 139–151, 2000
  29. Central Role of Peroxisome Proliferator-Activated Receptors in the Actions of Peroxisome Proliferators
    Annual Review of Pharmacology and Toxicology, vol. 40, no. 1, pp. 491–518, 2000
  30. Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice
    Carcinogenesis, vol. 20, no. 8, pp. 1583–1590, 1999
  31. Modulation of Testosterone-Metabolizing Hepatic Cytochrome P-450 Enzymes in Developing Sprague-Dawley Rats Following in Utero Exposure to p,p'-DDE
    Toxicology and Applied Pharmacology, vol. 158, no. 2, pp. 197–205, 1999
  32. Hepatic expression of acute-phase protein genes during carcinogenesis induced by peroxisome proliferators
    Molecular Carcinogenesis, vol. 26, no. 4, pp. 226–238, 1999
  33. Alteration of protein kinase C isoform-specific expression during rat hepatocarcinogenesis after exposure to the peroxisome proliferator WY-14,643
    Cancer Letters, vol. 137, no. 1, pp. 9–15, 1999
  34. Cloning genes responsive to a hepatocarcinogenic peroxisome proliferator chemical reveals novel targets of regulation
    Cancer Letters, vol. 134, no. 1, pp. 61–71, 1998
  35. Alterations in the GAL4 DNA-binding Domain Can Affect Transcriptional Activation Independent of DNA Binding
    Journal of Biological Chemistry, vol. 273, no. 22, pp. 13776–13780, 1998
  36. Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor  
    Endocrinology, vol. 139, no. 10, pp. 4252–4263, 1998
  37. Tissue-specific induction of 17 beta-hydroxysteroid dehydrogenase type IV by peroxisome proliferator chemicals is dependent on the peroxisome proliferator-activated receptor alpha
    Journal of Endocrinology, vol. 158, no. 2, pp. 237–246, 1998
  38. Peroxisome proliferators alter the expression of estrogen-metabolizing enzymes
    Biochimie, vol. 79, no. 2-3, pp. 151–162, 1997
  39. Effect on the expression of c-met, c-myc and PPAR-a in liver and liver tumors from rats chronically exposed to the hepatocarcinogenic peroxisome proliferator WY-14, 643
    Carcinogenesis, vol. 17, no. 6, pp. 1337–1341, 1996
  40. Identification of a Cell-Specific Transcription Activation Domain within the Human Ah Receptor Nuclear Translocator
    Toxicology and Applied Pharmacology, vol. 139, no. 2, pp. 272–280, 1996
  41. Overlapping but unique DNA binding specificities of the Ah receptor and constitutive dioxin-responsive element binding proteins from human keratinocytes
    Toxicology Letters, vol. 85, no. 2, pp. 67–75, 1996
  42. Reduction of Benzene Metabolism and Toxicity in Mice That Lack CYP2E1 Expression
    Toxicology and Applied Pharmacology, vol. 141, no. 1, pp. 205–213, 1996
  43. Mapping the peroxisome proliferator-activated receptor to Chromosome 15 in the mouse
    Mammalian Genome, vol. 5, no. 3, pp. 193–194, 1994
  44. Altering DNA-binding specificity of GAL4 requires sequences adjacent to the zinc finger
    Nature, vol. 340, no. 6236, Article ID 340724a0, 3 pages, 1989