Nina Luning Prak

Nina Luning Prak received her Bachelor's degree in molecular biology from Princeton University and her M.D. and Ph.D. degrees from the University of Pennsylvania. After completing residency training in clinical pathology and a Postdoctoral Fellowship in Genetics, she joined the University of Pennsylvania faculty as an Assistant Professor in the Department of Pathology and Laboratory Medicine. Her research interests include L1 retrotransposons and the analysis of immunoglobulin repertoire and receptor editing in B cell autoimmunity. Along with Dr. Ali Haoudi, Dr. Luning Prak served as a Guest Editor of a special issue of the Journal of Biomedicine and Biotechnology on L1 Retrotransposons.

Biography Updated on 17 March 2007

Articles in Scholarly Journals [Incomplete List]

  1. Consequences of receptor editing at the   locus: Multireactivity and light chain secretion
    Proceedings of the National Academy of Sciences, vol. 103, no. 30, pp. 11264–11269, 2006
  2. Gamma radiation increases endonuclease-dependent L1 retrotransposition in a cultured cell assay
    Nucleic Acids Research, vol. 34, no. 4, pp. 1196–1204, 2006
  3. The Potential Regulation of L1 Mobility by RNA Interference
    Journal of Biomedicine and Biotechnology, vol. 2006, Article ID 32713, 8 pages, 2006
  4. LINE-1 Retrotransposition: Impact on Genome Stability and Diversity and Human Disease
    Journal of Biomedicine and Biotechnology, vol. 2006, Article ID 37049, 2 pages, 2006
  5. DNA Damage and L1 Retrotransposition
    Journal of Biomedicine and Biotechnology, vol. 2006, Article ID 37285, 8 pages, 2006
  6. Point: Developing a Curriculum in Clinical Pathology
    Clinical Chemistry, vol. 52, no. 6, pp. 969–971, 2006
  7. More active human L1 retrotransposons produce longer insertions
    Nucleic Acids Research, vol. 32, no. 2, pp. 502–510, 2004
  8. Duffy antigen receptor and genetic susceptibility of African Americans to acute rejection and delayed function
    Kidney International, vol. 66, no. 3, pp. 1187–1192, 2004
  9. Tracking an embryonic L1 retrotransposition event
    Proceedings of the National Academy of Sciences, vol. 100, no. 4, pp. 1832–1837, 2003
  10. Regulation of Anti-Phosphatidylserine Antibodies
    Immunity, vol. 18, no. 2, pp. 185–192, 2003
  11. A nonsense mutation in Exon 3 results in the HLA-B null allele B*5127N
    Tissue Antigens, vol. 60, no. 3, pp. 262–265, 2002
  12. Analysis of B cell receptor production and rearrangement Part I. Light chain rearrangement
    Seminars in Immunology, vol. 14, no. 3, pp. 169–190, 2002
  13. Comment on Langman and Cohn
    Seminars in Immunology, vol. 14, no. 3, pp. 231–232, 2002
  14. D is for different—differences between H and L chain rearrangement
    Seminars in Immunology, vol. 14, no. 3, pp. 239–241, 2002
  15. Editors and Editing of Anti-DNA Receptors
    Immunity, vol. 15, no. 6, pp. 947–957, 2001
  16. Nature Reviews Genetics, vol. 1, no. 2, pp. 134–144, 2000
  17. Determination of L1 retrotransposition kinetics in cultured cells
    Nucleic Acids Research, vol. 28, no. 6, pp. 1418–1423, 2000
  18. Somatic Mutation and Light Chain Rearrangement Generate Autoimmunity in Antisingle-stranded DNA Transgenic MRL/lpr Mice
    Journal of Experimental Medicine, vol. 190, no. 5, pp. 691–704, 1999
  19. Editing Disease-Associated Autoantibodies
    Immunity, vol. 6, no. 1, pp. 97–105, 1997
  20. Immunoglobulin heavy chain gene replacement: A mechanism of receptor editing
    Immunity, vol. 3, no. 6, pp. 747–755, 1995
  21. Light chain replacement: a new model for antibody gene rearrangement
    Journal of Experimental Medicine, vol. 182, no. 2, pp. 541–548, 1995
  22. Light chain editing in kappa-deficient animals: a potential mechanism of B cell tolerance
    Journal of Experimental Medicine, vol. 180, no. 5, pp. 1805–1815, 1994