Mark von Itzstein

Personal Home Page

http://www.griffith.edu.au/er/campaign/tutu/content_vonitzstein.html

Articles in Scholarly Journals [Incomplete List]

  1. Avian Influenza H5-Containing Virus-Like Particles (VLPs): Host-Cell Receptor Specificity by STD NMR Spectroscopy
    Angewandte Chemie International Edition, vol. 47, no. 10, pp. 1910–1912, 2008
  2. Influenza C virus and bovine coronavirus esterase reveal a similar catalytic mechanism: new insights for drug discovery
    Glycoconjugate Journal, vol. 25, no. 5, pp. 393–399, 2008
  3. Avian influenza virus, a very sticky situation
    Current Opinion in Chemical Biology, vol. 12, no. 1, pp. 102–108, 2008
  4. Hot, sweet and sticky: the glycobiology of Plasmodium falciparum
    Trends in Parasitology, vol. 24, no. 5, pp. 210–218, 2008
  5. Targeting the expression of functional murine CMP-sialic acid transporter to the E. coli inner membrane
    Biochemical and Biophysical Research Communications, vol. 362, no. 3, pp. 779–784, 2007
  6. The evolution of galactose a2,3-sialyltransferase: Cionaintestinalis ST3GAL I/II and Takifugu rubripes ST3GAL II sialylate Galß1,3GalNAc structures on glycoproteins but not glycolipids
    Glycoconjugate Journal, 2007
  7. Insight into Host Cell Carbohydrate-recognition by Human and Porcine Rotavirus from Crystal Structures of the Virion Spike Associated Carbohydrate-binding Domain (VP8)
    Journal of Molecular Biology, vol. 367, no. 4, pp. 1215–1226, 2007
  8. Anti-Influenza Drug Discovery: Are We Ready for the Next Pandemic?
    Advances in Carbohydrate Chemistry and Biochemistry, vol. 61, pp. 293–352, 2007
  9. The war against influenza: discovery and development of sialidase inhibitors
    Nature Reviews Drug Discovery, vol. 6, no. 12, Article ID nrd2400, 7 pages, 2007
  10. Endosialidase NF Appears To Bind PolySia DP5 in a Helical Conformation
    ChemBioChem, vol. 7, no. 12, pp. 1875–1877, 2006
  11. Unsaturated N-acetyl- D-glucosaminuronic acid glycosides as inhibitors of influenza virus sialidase
    Glycoconjugate Journal, vol. 23, no. 1-2, pp. 127–133, 2006
  12. Structural analysis of a designed inhibitor complexed with the hemagglutinin-neuraminidase of Newcastle disease virus
    Glycoconjugate Journal, vol. 23, no. 1-2, pp. 135–141, 2006
  13. A 1H STD NMR spectroscopic investigation of sialylnucleoside mimetics as probes of CMP-Kdn synthetase
    Glycoconjugate Journal, vol. 23, no. 5-6, pp. 371–375, 2006
  14. The synthesis and biological evaluation of lactose-based sialylmimetics as inhibitors of rotaviral infection
    Bioorganic & Medicinal Chemistry, vol. 14, no. 3, pp. 739–757, 2006
  15. Molecular Cloning of the Leishmania major UDP-glucose Pyrophosphorylase, Functional Characterization, and Ligand Binding Analyses Using NMR Spectroscopy
    Journal of Biological Chemistry, vol. 281, no. 24, pp. 16314–16322, 2006
  16. STD NMR spectroscopy and molecular modeling investigation of the binding of N-acetylneuraminic acid derivatives to rhesus rotavirus VP8* core
    Glycobiology, vol. 17, no. 1, pp. 68–81, 2006
  17. Crystallization and preliminary X-ray diffraction analysis of the sialic acid-binding domain (VP8*) of porcine rotavirus strain CRW-8
    Acta Crystallographica Section F Structural Biology and Crystallization Communications, vol. 61, no. 6, pp. 617–620, 2005
  18. Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the VP8* carbohydrate-binding protein of the human rotavirus strain Wa
    Acta Crystallographica Section F Structural Biology and Crystallization Communications, vol. 61, no. 11, pp. 989–993, 2005
  19. Functional expression of the CMP-sialic acid transporter in Escherichia coli and its identification as a simple mobile carrier
    Glycobiology, vol. 16, no. 1, pp. 73–81, 2005
  20. Lysosomal Sialidase (Neuraminidase-1) Is Targeted to the Cell Surface in a Multiprotein Complex That Facilitates Elastic Fiber Assembly
    Journal of Biological Chemistry, vol. 281, no. 6, pp. 3698–3710, 2005
  21. An investigation of the activity of recombinant rat skeletal muscle cytosolic sialidase
    FEBS Letters, vol. 579, no. 5, pp. 1034–1038, 2005
  22. An approach towards the synthesis of sialyl nucleoside mimetics
    Tetrahedron: Asymmetry, vol. 16, no. 8, pp. 1425–1434, 2005
  23. Probing a CMP-Kdn synthetase by H, P, and STD NMR spectroscopy
    Biochemical and Biophysical Research Communications, vol. 327, no. 2, pp. 565–570, 2005
  24. Towards the synthesis of aryl glucuronides as potential heparanase probes. An interesting outcome in the glycosidation of glucuronic acid with 4-hydroxycinnamic acid
    Carbohydrate Research, vol. 340, no. 13, pp. 2077–2085, 2005
  25. An efficient approach to -acetyl--glucosaminuronic acid-based sialylmimetics as potential sialidase inhibitors
    Bioorganic & Medicinal Chemistry Letters, vol. 14, no. 22, pp. 5555–5558, 2004
  26. Saturation transfer difference (STD)1H-NMR experiments and in silico docking experiments to probe the binding ofN-acetylneuraminic acid and derivatives toVibrio cholerae sialidase
    Proteins: Structure, Function, and Bioinformatics, vol. 56, no. 2, pp. 346–353, 2004
  27. Sialic Acid Recognition by Vibrio cholerae Neuraminidase
    Journal of Biological Chemistry, vol. 279, no. 39, pp. 40819–40826, 2004
  28. NMR spectroscopic and molecular modeling investigations of the trans-sialidase from Trypanosoma cruzi
    Glycobiology, vol. 14, no. 10, pp. 895–907, 2004
  29. Second Sialic Acid Binding Site in Newcastle Disease Virus Hemagglutinin-Neuraminidase: Implications for Fusion
    Journal of Virology, vol. 78, no. 7, pp. 3733–3741, 2004
  30. Recent Strategies in the Search for New Anti-Influenza Therapies
    Current Drug Targets, vol. 4, no. 5, pp. 389–408, 2003
  31. Organic Letters, vol. 5, no. 23, pp. 4365–4368, 2003
  32. Recent Advances in the Synthesis of Sialic Acid Derivatives and Sialylmimetics as Biological Probes
    Chemical Reviews, vol. 102, no. 2, pp. 471–490, 2002
  33. Rapid, clean, and mild O-acetylation of alcohols and carbohydrates in an ionic liquid
    Chemical Communications, no. 7, pp. 714–715, 2002
  34. A convenient synthesis of C-galactofuranosylic compounds (C-galactofuranosides)
    Carbohydrate Research, vol. 337, no. 21-23, pp. 2017–2022, 2002
  35. Synthesis of C-3 nitrogen-containing derivatives of N-acetyl-a,ß-?-mannosamine as substrates for N-acetylneuraminic acid aldolase
    Carbohydrate Research, vol. 332, no. 2, pp. 133–139, 2001
  36. Synthesis and Biological Evaluation of Sialylmimetics as Rotavirus Inhibitors
    Journal of Medicinal Chemistry, vol. 44, no. 20, pp. 3292–3301, 2001
  37. A Unique Sialidase That Cleaves the Neu5Gca2?5-OglycolylNeu5Gc Linkage: Comparison of Its Specificity with That of Three Microbial Sialidases toward Four Sialic Acid Dimers
    Biochemical and Biophysical Research Communications, vol. 280, no. 1, pp. 104–109, 2001
  38. THE SYNTHESIS OF C-9 MODIFIED DERIVATIVES OF THE a-METHYL GLYCOSIDE OF KDN METHYL ESTER
    Journal of Carbohydrate Chemistry, vol. 20, no. 2, pp. 227–238, 2001
  39. BROMOHYDROXYLATION OF GLYCALS—AN INVESTIGATION INTO THE REACTION OF SOME 4-N-ACYLATED DERIVATIVES OF METHYL 5-ACETAMIDO-7,8,9-TRI-O-ACETYL-2,6-ANHYDRO-3,4,5-TRIDEOXY-D-GLYCERO-D-GALACTO-NON-2-ENONATE AND ITS 4-EPIMER
    Journal of Carbohydrate Chemistry, vol. 20, no. 5, pp. 359–374, 2001
  40. THE SYNTHESIS OF SOME C-4 AND C-9 SUBSTITUTED DERIVATIVES OF KDN2EN METHYL ESTER
    Journal of Carbohydrate Chemistry, vol. 20, no. 7&8, pp. 507–517, 2001
  41. Analysis of inhibitor binding in influenza virus neuraminidase
    Protein Science, vol. 10, no. 4, pp. 689–696, 2001
  42. Australian Journal of Chemistry, vol. 54, no. 11, p. 663, 2001
  43. A High-Throughput Assay for Rat Liver Golgi and Saccharomyces cerevisiae-Expressed Murine CMP-N-Acetylneuraminic Acid Transport Proteins
    Analytical Biochemistry, vol. 285, no. 1, pp. 21–32, 2000
  44. A one-pot synthesis of novel N,N-dialkyl-S-glycosylsulfenamides
    Carbohydrate Research, vol. 328, no. 3, pp. 287–292, 2000
  45. Rapid access to uronic acid-based mimetics of Kdn2en from ?-glucurono-6,3-lactone
    Carbohydrate Research, vol. 328, no. 4, pp. 445–448, 2000
  46. The design, synthesis and biological evaluation of neuraminic acid-based probes of Vibrio cholerae sialidase
    Tetrahedron: Asymmetry, vol. 11, no. 1, pp. 53–73, 2000
  47. Preliminary 1H NMR investigation of sialic acid transfer by the trans-sialidase from Trypanosoma cruzi
    Bioorganic & Medicinal Chemistry Letters, vol. 10, no. 24, pp. 2791–2794, 2000
  48. Synthesis and evaluation of C-9 modified N-acetylneuraminic acid derivatives as substrates for N-acetylneuraminic acid aldolase
    Bioorganic & Medicinal Chemistry, vol. 8, no. 3, pp. 657–664, 2000
  49. Synthesis of ? acids as mimetics of 2,3-unsaturated sialic acids for sialidase inhibition
    Bioorganic & Medicinal Chemistry Letters, vol. 9, no. 14, pp. 2065–2068, 1999
  50. The synthesis and evaluation of novel sialic acid analogues bound to matrices for the purification of sialic acid-recognising proteins
    Carbohydrate Research, vol. 322, no. 3-4, pp. 201–208, 1999
  51. Organic Letters, vol. 1, no. 3, pp. 443–446, 1999
  52. Glycoconjugate Journal, vol. 16, no. 1, pp. 13–17, 1999
  53. Synthesis of Carbohydrates with an Anomeric Thiol Moiety for Elaboration into Metabolically Stable Thioglycosides
    Journal of Carbohydrate Chemistry, vol. 18, no. 8, pp. 937–959, 1999
  54. Glycoconjugate Journal, vol. 15, no. 7, pp. 663–669, 1998
  55. Journal of Organic Chemistry, vol. 62, no. 11, pp. 3500–3504, 1997
  56. The formation of anhydrides in the Mitsunobu reaction
    Tetrahedron, vol. 53, no. 11, pp. 3933–3942, 1997
  57. A facile synthesis of a useful ? from 2-acetamido-2-deoxy-?-glucose
    Carbohydrate Research, vol. 300, no. 2, pp. 171–174, 1997
  58. A regio- and stereo-selective introduction of azide at C-4 of 2,3-unsaturated N-acetylneuraminic acids
    Carbohydrate Research, vol. 302, no. 3-4, pp. 237–240, 1997
  59. The chemoenzymatic synthesis of 9-substituted 3,9-dideoxy-?-glycero-?-galacto-2-nonulosonic acids
    Carbohydrate Research, vol. 305, no. 3-4, pp. 323–329, 1997
  60. Catalysis by a New Sialidase, Deaminoneuraminic Acid Residue-cleaving Enzyme (KDNase Sm), Initially Forms a Less Stable alpha -Anomer of 3-Deoxy-D-glycero-D-galacto-nonulosonic Acid and Is Strongly Inhibited by the Transition State Analogue, 2-Deoxy-2,3-didehydro-D-glycero-D-galacto-2-nonulopyranosonic Acid, but Not by 2-Deoxy-2,3-didehydro-N-acetylneuraminic Acid
    Journal of Biological Chemistry, vol. 272, no. 9, pp. 5452–5456, 1997
  61. Synthesis of C-4 Halogen-Substituted Derivatives of Neu5Ac2en and KDN2en
    Synthesis, vol. 1997, no. 10, pp. 1185–1188, 1997
  62. A New Facile Synthesis of C-4 Nitrogen-Containing Derivatives of KDN2en and KDO2en
    Synthesis, vol. 1997, no. 07, pp. 769–772, 1997
  63. Design and synthesis of carbohydrate-based inhibitors of protein—carbohydrate interactions
    Current Opinion in Structural Biology, vol. 6, no. 5, pp. 703–709, 1996
  64. A facile and direct entry to functionalised Neu5Ac2En derivatives from the methyl ketoside of Neu5Ac methyl esters
    Chemical Communications, no. 17, p. 2017, 1996
  65. A Study of the Active Site of Influenza Virus Sialidase: An Approach to the Rational Design of Novel Anti-influenza Drugs
    Journal of Medicinal Chemistry, vol. 39, no. 2, pp. 388–391, 1996
  66. Journal of Medicinal Chemistry, vol. 39, no. 6, pp. 1314–1320, 1996
  67. The first synthesis of an alkylmercury containing N-acetylneuraminic acid derivative
    Tetrahedron Letters, vol. 37, no. 40, pp. 7307–7310, 1996
  68. Synthesis and influenza virus sialidase inhibitory activity of analogues of 4-guanidino-Neu5Ac2en (GG167) with modified 5-substituents
    European Journal of Medicinal Chemistry, vol. 31, no. 2, pp. 143–150, 1996
  69. Decarboxylation of a sialic acid derivative
    Carbohydrate Research, vol. 282, no. 1, pp. 181–187, 1996
  70. The reaction of the peracetate methyl esters of N-acetylneuraminic acid (Neu5Ac), 3-deoxy-?-glycero-?-galacto-2-nonulosonic acid (Kdn), and 3-deoxy-?-manno-2-octulosonic acid (Kdo) with trimethylsilyl trifluoromethanesulfonate
    Carbohydrate Research, vol. 289, pp. 67–75, 1996
  71. A structural and energetics analysis of the binding of a series of N-acetylneuraminic-acid-based inhibitors to influenza virus sialidase
    Journal of Computer-Aided Molecular Design, vol. 10, no. 3, pp. 233–246, 1996
  72. A1H NMR investigation of the hydrolysis of a synthetic substrate by KDN-sialidase fromCrassostrea virginica
    Glycoconjugate Journal, vol. 13, no. 6, pp. 927–931, 1996
  73. An improved synthesis of an important S-sialylnucleoside analogue
    Carbohydrate Research, vol. 266, no. 2, pp. 269–272, 1995
  74. Synthesis of 4-substituted-2-acetamido-2,4-dideoxy-mannopyranoses using 1,6-anhydro sugar chemistry
    Carbohydrate Research, vol. 274, pp. 29–44, 1995
  75. Towards the synthesis of sialic acid-based Salmonella typhimurium sialidase inhibitors
    Carbohydrate Research, vol. 274, pp. 279–283, 1995
  76. Effect of substrate aglycon on enzyme mechanism in the reaction of sialidase from influenza virus
    FEBS Letters, vol. 372, no. 2-3, pp. 148–150, 1995
  77. The first synthesis of a C-7 nitrogen-containing sialic acid analogue, ? acid (7-azido-7-deoxy-Neu5Ac)
    Tetrahedron Letters, vol. 36, no. 6, pp. 957–960, 1995
  78. Biochemistry, vol. 34, no. 26, pp. 8299–8308, 1995
  79. Journal of the American Chemical Society, vol. 117, no. 15, pp. 4214–4217, 1995
  80. Journal of Medicinal Chemistry, vol. 37, no. 5, pp. 616–624, 1994
  81. A simple method for the preparation of thioglycosides ofN-acetylneuraminic acid
    Carbohydrate Research, vol. 259, no. 2, pp. 293–299, 1994
  82. The synthesis of 2,3-didehydro-2,4-dideoxy-4-guanidinyl-N-acetylneuraminic acid: a potent influenza virus sialidase inhibitor
    Carbohydrate Research, vol. 259, no. 2, pp. 301–305, 1994
  83. Inhibition of sialidases from viral, bacterial and mammalian sources by analogues of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid modified at the C-4 position
    Glycoconjugate Journal, vol. 10, no. 1, pp. 40–44, 1993
  84. A convenient method for the introduction of nitrogen and sulfur at C-4 on a sialic acid analogue
    Carbohydrate Research, vol. 244, no. 1, pp. 181–185, 1993
  85. Rational design of potent sialidase-based inhibitors of influenza virus replication
    Nature, vol. 363, no. 6428, Article ID 363418a0, 5 pages, 1993
  86. High-level production and purification of Escherichia coliN-Acetylneuraminic acid aldolase (EC 4.1.3.3)
    Protein Expression and Purification, vol. 3, no. 5, pp. 434–440, 1992
  87. A one-step synthesis of 6-S-acetyl-6-deoxy-1,2:3,4-di-O-isopropylidene-6-thio-α-?-galactopyranose
    Carbohydrate Research, vol. 208, no. 1, pp. 287–288, 1990
  88. The reaction of diols with triphenylphosphine and di-isopropyl azodicarboxylate. Part 2. Formation of cyclic phosphoranes from 1,5?1,12-diols
    Journal of the Chemical Society, Perkin Transactions 1, p. 2057, 1987
  89. The reaction of diols with triphenylphosphine and di-isopropyl azodicarboxylate. Part 1. Formation of cyclic phosphoranes from 1,3- and 1,4- diols
    Journal of the Chemical Society, Perkin Transactions 1, p. 437, 1986
  90. A novel phosphorus ? oxygen phenyl migration: triphenylphosphine dioxide as a reaction intermediate
    Journal of the Chemical Society, Chemical Communications, no. 4, p. 164, 1983