Anton Enright

Anton Enright is an Investigator at the Wellcome Trust Sanger Institute. He was born in Dublin, Ireland, where he studied genetics at Trinity College. After completing his undergraduate degree, Anton studied for his Ph.D. degree at the European Bioinformatics Institute and the University of Cambridge. Working there with Dr. Christos Ouzounis, he has specialized in protein sequence annotation and clustering, the prediction of protein-protein interactions, and visualization and analysis of protein networks. Upon completion of his Ph.D. degree, he moved to the laboratory of Dr. Chris Sander at Memorial Sloan-Kettering Cancer Center in New York. At MSKCC, he turned his attention to the analysis and prediction of regulatory targets for microRNAs. Anton returned to Cambridge in 2004 to start his own laboratory at the Wellcome Trust Sanger Institute. His research interests include the large-scale clustering and classification of protein sequences, analysis of regulatory and interaction networks, and the accurate detection of microRNA target interactions.

Biography Updated on 4 January 2008

Personal Home Page

http://www.sanger.ac.uk/Teams/Team101/

Articles in Scholarly Journals [Incomplete List]

  1. A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway
    Genes & Development, vol. 21, no. 16, pp. 1999–2004, 2007
  2. miRBase: tools for microRNA genomics
    Nucleic Acids Research, 2007
  3. Genomic analysis of human microRNA transcripts
    Proceedings of the National Academy of Sciences, vol. 104, no. 45, pp. 17719–17724, 2007
  4. microRNA-155 Regulates the Generation of Immunoglobulin Class-Switched Plasma Cells
    Immunity, vol. 27, no. 6, pp. 847–859, 2007
  5. Prediction of microRNA targets
    Drug Discovery Today, vol. 12, no. 11-12, pp. 452–458, 2007
  6. Requirement of bic/microRNA-155 for Normal Immune Function
    Science, vol. 316, no. 5824, pp. 608–611, 2007
  7. Construction, Visualisation, and Clustering of Transcription Networks from Microarray Expression Data
    PLoS Computational Biology, vol. 3, no. 10, p. e206, 2007
  8. Computational Prediction of Protein–Protein Interactions
    Molecular Biotechnology, vol. 38, no. 1, pp. 1–17, 2007
  9. Denoising inferred functional association networks obtained by gene fusion analysis
    BMC Genomics, vol. 8, no. 1, p. 460, 2007
  10. Cycloadditions as a Method for Oligonucleotide Conjugation
    Current Organic Synthesis, vol. 3, no. 1, pp. 9–17, 2006
  11. Genome Biology, vol. 7, no. 4, p. R27, 2006
  12. Zebrafish MiR-430 Promotes Deadenylation and Clearance of Maternal mRNAs
    Science, vol. 312, no. 5770, pp. 75–79, 2006
  13. miRBase: microRNA sequences, targets and gene nomenclature
    Nucleic Acids Research, vol. 34, no. 90001, pp. D140–D144, 2006
  14. MicroRNAs Regulate Brain Morphogenesis in Zebrafish
    Science, vol. 308, no. 5723, pp. 833–838, 2005
  15. CoGenT++: an extensive and extensible data environment for computational genomics
    Bioinformatics, vol. 21, no. 19, pp. 3806–3810, 2005
  16. MagicMatch--cross-referencing sequence identifiers across databases
    Bioinformatics, vol. 21, no. 16, pp. 3429–3430, 2005
  17. BioLayoutJava
    Applied Bioinformatics, vol. 4, no. 1, pp. 71–74, 2005
  18. Human MicroRNA Targets
    PLoS Biology, vol. 2, no. 11, p. e363, 2004
  19. Identification of Virus-Encoded MicroRNAs
    Science, vol. 304, no. 5671, pp. 734–736, 2004
  20. Classification schemes for protein structure and function
    Nature Reviews Genetics, vol. 4, no. 7, Article ID nrg1113, 11 pages, 2003
  21. Protein families and TRIBES in genome sequence space
    Nucleic Acids Research, vol. 31, no. 15, pp. 4632–4638, 2003
  22. COmplete GENome Tracking (COGENT): a flexible data environment for computational genomics
    Bioinformatics, vol. 19, no. 11, pp. 1451–1452, 2003
  23. Evaluation of annotation strategies using an entire genome sequence
    Bioinformatics, vol. 19, no. 6, pp. 717–726, 2003
  24. Genome Biology, vol. 4, no. 2, p. 401, 2003
  25. Genome Biology, vol. 5, no. 1, p. R1, 2003
  26. Detection of functional modules from protein interaction networks
    Proteins: Structure, Function, and Bioinformatics, vol. 54, no. 1, pp. 49–57, 2003
  27. Mapping functional associations in the entire genome ofDrosophila melanogaster using fusion analysis
    Comparative and Functional Genomics, vol. 4, no. 3, pp. 337–341, 2003
  28. An efficient algorithm for large-scale detection of protein families
    Nucleic Acids Research, vol. 30, no. 7, pp. 1575–1584, 2002
  29. BioLayout--an automatic graph layout algorithm for similarity visualization
    Bioinformatics, vol. 17, no. 9, pp. 853–854, 2001
  30. Transcription-associated protein families are primarily taxon-specific
    Bioinformatics, vol. 17, no. 1, pp. 95–97, 2001
  31. GeneRAGE: a robust algorithm for sequence clustering and domain detection
    Bioinformatics, vol. 16, no. 5, pp. 451–457, 2000
  32. CAST: an iterative algorithm for the complexity analysis of sequence tracts
    Bioinformatics, vol. 16, no. 10, pp. 915–922, 2000
  33. Estimation of synteny conservation and genome compaction between pufferfish (Fugu) and human
    Yeast, vol. 17, no. 1, pp. 22–36, 2000
  34. Nature, vol. 402, no. 6757, pp. 86–90, 1999