Hirotada Akiho holds the M.D. and Ph.D. degrees. He is the Chief Director of the Department of Gastroenterology, Kitakyushu Municipal Medical Center and a Teaching Staff at Kyushu University Hospital, Fukuoka, Japan. His research interests are in the fields of GI immuno-physiology in the intestinal inflammation, mechanisms and therapeutic strategies of IBD and IBS, and evaluation of the gastric emptying for gastric cancer patients and donors/recipients of liver transplantation. He mainly focused on mucosal injury and inflammation in the gastrointestinal (GI) tract associated with activation of immune system and alteration in the intestinal physiology which includes changes in motility, mucus production, and neuroendocrine function. Using the model of T cell-induced enteropathy, his research involves studies to elucidate the immunological basis of altered intestinal physiology and pathophysiology specifically the roles of T cell subsets, cytokines, and chemokines in the regulation of enteroendocrine cells biology, and intestinal muscle function in the GI inflammation. In addition, his research also includes investigations on immunological strategies to modulate intestinal inflammation in experimental colitis model. Using these models, we investigate the mechanisms and therapeutic strategies of postinflammatory IBS and IBD. We evaluate the role of GI microbiota and cytokines in IBS. We also evaluate the gastric emptying for gastric cancer patients before and after ESD and donors/recipients before and after liver transplantation. He is working at the GI Center Hospital in Kitakyushu City. Clinically he sees many GI cancer and IBD patients as the Chief of the department. He is teaching and supervising the GI doctors, residents, graduate school students, and medical school students and nurses.
Biography Updated on 28 April 2011