Yanjin Zhang graduated from Iowa State University with a Ph.D degree in immunobiology in 1998. Currently, he serves as an Assistant Professor in University of Maryland, College Park, Md, USA. His research interests are on molecular virology and viral pathogenesis and his current projects are on elucidating virus-cell interactions of hepatitis E virus and porcine reproductive and respiratory syndrome virus, and on exploring nucleic acid-based strategies against Kaposi‘s sarcoma-associated herpesvirus and hepatitis E virus. The strategy he is currently exploring is a new generation of antisense compounds, phosphodiamidate morpholino oligomers (PMOs). PMOs are analogs of short DNA oligomers with modified sugar and phosphate moieties in the nucleotides, resulting in highly specific binding and complete resistance to nucleases in the host. Their safety, efficacy, and bioavailability suggest promising applications in the clinical arena as anticancer, antivirals, and other applications to block target gene expression.
Biography Updated on 13 March 2012