John Stegeman
Personal Home Page
http://www.whoi.edu/dept/profile.go?id=1283
Articles in Scholarly Journals [Incomplete List]
- Basal and 3,3',4,4',5-pentachlorobiphenyl-induced expression of cytochrome P450 1A, 1B and 1C genes in zebrafish
Toxicology and Applied Pharmacology, vol. 221, no. 1, pp. 29–41, 2007 - Fundulus as the premier teleost model in environmental biology: Opportunities for new insights using genomics
Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, vol. 2, no. 4, pp. 257–286, 2007 - Ensemble Modeling of Substrate Binding to Cytochromes P450: Analysis of Catalytic Differences between CYP1A Orthologs,
Biochemistry, vol. 46, no. 10, pp. 2640–2654, 2007 - Correlates of Cytochrome P450 1A1 Expression in Bottlenose Dolphin (Tursiops truncatus) Integument Biopsies
Toxicological Sciences, vol. 97, no. 1, pp. 111–119, 2007 - Role of AHR2 in the Expression of Novel Cytochrome P450 1 Family Genes, Cell Cycle Genes, and Morphological Defects in Developing Zebra Fish Exposed to 3,3',4,4',5-Pentachlorobiphenyl or 2,3,7,8-Tetrachlorodibenzo-p-dioxin
Toxicological Sciences, vol. 100, no. 1, pp. 180–193, 2007 - Cytochrome P450 1 Genes in Early Deuterostomes (Tunicates and Sea Urchins) and Vertebrates (Chicken and Frog): Origin and Diversification of the CYP1 Gene Family
Molecular Biology and Evolution, vol. 24, no. 12, pp. 2619–2631, 2007 - Demethylation of the Pesticide Methoxychlor in Liver and Intestine from Untreated, Methoxychlor-Treated and 3-Methylcholanthrene-Treated Channel Catfish (Ictalurus punctatus): Evidence for roles of CYP1 and 3A family isozymes
Drug Metabolism and Disposition, 2006 - The Genome of the Sea Urchin Strongylocentrotus purpuratus
Science, vol. 314, no. 5801, pp. 941–952, 2006 - EVALUATING CYTOCHROME P450 IN LESSER SCAUP (AYTHYA AFFINIS) AND TREE SWALLOW (TACHYCINETA BICOLOR) BY MONOOXYGENASE ACTIVITY AND IMMUNOHISTOCHEMISTRY: POSSIBLE NONLETHAL ASSESSMENT BY SKIN IMMUNOHISTOCHEMISTRY
Environmental Toxicology and Chemistry, vol. 25, no. 10, p. 2613, 2006 - Biomarkers Signal Contaminant Effects on the Organs of English Sole (Parophrys vetulus) from Puget Sound
Environmental Health Perspectives, 2006 - Cytochrome P450 1A4 and 1A5 in Common Cormorant (Phalacrocorax carbo): Evolutionary Relationships and Functional Implications Associated with Dioxin and Related Compounds
Toxicological Sciences, vol. 92, no. 2, pp. 394–408, 2006 - Retinal Neuronal Cell is a Toxicological Target of Tributyltin in Developing Zebrafish
Journal of Veterinary Medical Science, vol. 68, no. 6, pp. 573–579, 2006 - Molecular Mechanisms of 2,3,7,8-Tetrachlorodibenzo- p -Dioxin Cardiovascular Embryotoxicity
Drug Metabolism Reviews, vol. 38, no. 1-2, pp. 261–289, 2006 - Environmental Science & Technology, vol. 40, no. 8, pp. 2851–2858, 2006
- Environmental Science & Technology, vol. 40, no. 20, pp. 6513–6517, 2006
- On the species-specific biotransformation of dibenzo[a,l]pyrene
Chemico-Biological Interactions, vol. 161, no. 1, pp. 37–48, 2006 - Muscular contractions in the zebrafish embryo are necessary to reveal thiuram-induced notochord distortions
Toxicology and Applied Pharmacology, vol. 212, no. 1, pp. 24–34, 2006 - The chemical defensome: Environmental sensing and response genes in the Strongylocentrotus purpuratus genome
Developmental Biology, vol. 300, no. 1, pp. 366–384, 2006 - Cytochrome P4501A is induced in endothelial cell lines from the kidney and lung of the bottlenose dolphin, Tursiops truncatus
Aquatic Toxicology, vol. 76, no. 3-4, pp. 295–305, 2006 - Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners
Aquatic Toxicology, vol. 77, no. 4, pp. 422–432, 2006 - Isolation and phylogeny of novel cytochrome P450 genes from tunicates (Ciona spp.): A CYP3 line in early deuterostomes?
Molecular Phylogenetics and Evolution, vol. 40, no. 3, pp. 760–771, 2006 - A Revised Evolutionary History of the CYP1A Subfamily: Gene Duplication, Gene Conversion, and Positive Selection
Journal of Molecular Evolution, vol. 62, no. 6, pp. 708–717, 2006 - Characterization of a cetacean aromatase (CYP19) and the phylogeny and functional conservation of vertebrate aromatase
General and Comparative Endocrinology, vol. 140, no. 1, pp. 74–83, 2005 - The new vertebrate CYP1C family: Cloning of new subfamily members and phylogenetic analysis
Biochemical and Biophysical Research Communications, vol. 331, no. 4, pp. 1016–1024, 2005 - CYTOCHROME P4501A INDUCED DIFFERENTIALLY IN ENDOTHELIAL CELLS CULTURED FROM DIFFERENT ORGANS OF ANGUILLA ROSTRATA
In Vitro Cellular & Developmental Biology - Animal, vol. 41, no. 1, p. 57, 2005 - Cardiovascular Gene Expression Profiles of Dioxin Exposure in Zebrafish Embryos
Toxicological Sciences, vol. 85, no. 1, pp. 683–693, 2005 - Systemic Effects of Arctic Pollutants in Beluga Whales Indicated by CYP1A1 Expression
Environmental Health Perspectives, 2005 - Induction of Cetacean Cytochrome P4501A1 by -Naphthoflavone Exposure of Skin Biopsy Slices
Toxicological Sciences, vol. 80, no. 2, pp. 268–275, 2004 - CYTOCHROME P450 1A1 EXPRESSION IN CETACEAN INTEGUMENT: IMPLICATIONS FOR DETECTING CONTAMINANT EXPOSURE AND EFFECTS
Marine Mammal Science, vol. 20, no. 3, pp. 554–566, 2004 - Environmental Science & Technology, vol. 38, no. 19, pp. 4928–4936, 2004
- Histological analysis of acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in zebrafish
Aquatic Toxicology, vol. 66, no. 1, pp. 25–38, 2004 - Induction of cytochrome P450 1A is required for circulation failure and edema by 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish
Biochemical and Biophysical Research Communications, vol. 304, no. 2, pp. 223–228, 2003 - Phylogenetic Analysis of the Cytochrome P450 3 (CYP3) Gene Family
Journal of Molecular Evolution, vol. 57, no. 2, pp. 200–211, 2003 - Aryl Hydrocarbon Receptor 2 Mediates 2,3,7,8-Tetrachlorodibenzo-p-dioxin Developmental Toxicity in Zebrafish
Toxicological Sciences, vol. 76, no. 1, pp. 138–150, 2003 - Role of Aryl Hydrocarbon Receptor in Mesencephalic Circulation Failure and Apoptosis in Zebrafish Embryos Exposed to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin
Toxicological Sciences, vol. 77, no. 1, pp. 109–116, 2003 - Biomarkers in Fish from Prince William Sound and the Gulf of Alaska: 1999-2000
Environmental Science & Technology, vol. 37, no. 18, pp. 4043–4051, 2003 - Identification and regulation of a new vertebrate cytochrome P450 subfamily, the CYP2Ps, and functional characterization of CYP2P3, a conserved arachidonic acid epoxygenase/19-hydroxylase
Archives of Biochemistry and Biophysics, vol. 411, no. 2, pp. 223–234, 2003 - Serum withdrawal leads to reduced aryl hydrocarbon receptor expression and loss of cytochrome P4501A inducibility in PLHC-1 cells
Biochemical Pharmacology, vol. 63, no. 8, pp. 1405–1414, 2002 - Relationships among the cell cycle, cell proliferation, and aryl hydrocarbon receptor expression in PLHC-1 cells
Aquatic Toxicology, vol. 58, no. 3-4, pp. 201–213, 2002 - Expression of P-glycoprotein in killifish (Fundulus heteroclitus) exposed to environmental xenobiotics
Aquatic Toxicology, vol. 59, no. 3-4, pp. 237–251, 2002 - Expression of P-glycoprotein and cytochrome P450 1A in intertidal fish (Anoplarchus purpurescens) exposed to environmental contaminants
Aquatic Toxicology, vol. 60, no. 1-2, pp. 17–32, 2002 - 2,3,7,8-Tetrachlorodibenzo-p-dioxin Toxicity in the Zebrafish Embryo: Local Circulation Failure in the Dorsal Midbrain Is Associated with Increased Apoptosis
Toxicological Sciences, vol. 69, no. 1, pp. 191–201, 2002 - Transcriptional Activation of Cytochrome P450 CYP2C45 by Drugs Is Mediated by the Chicken Xenobiotic Receptor (CXR) Interacting with a Phenobarbital Response Enhancer Unit
Journal of Biological Chemistry, vol. 277, no. 18, pp. 15647–15653, 2002 - Tissue-Specific Expression of AHR2, ARNT2, and CYP1A in Zebrafish Embryos and Larvae: Effects of Developmental Stage and 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure
Toxicological Sciences, vol. 68, no. 2, pp. 403–419, 2002 - Species-specific responses of constitutively active receptor (CAR)–CYP2B coupling: lack of CYP2B inducer-responsive nuclear translocation of CAR in marine teleost, scup (Stenotomus chrysops)
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, vol. 131, no. 4, pp. 501–510, 2002 - cDNA Cloning and Expressions of Cytochrome P450 1A in Zebrafish Embryos
Journal of Veterinary Medical Science, vol. 64, no. 9, pp. 829–833, 2002 - Induction of cytochrome P450 1A1 expression in captive river otters fed Prudhoe Bay crude oil: evaluation by immunohistochemistry and quantitative RT-PCR
Biomarkers, vol. 6, no. 3, pp. 218–235, 2001 - IMMUNOHISTOCHEMICAL LOCALIZATION OF CYTOCHROME P4501A INDUCED BY 3,3′,4,4′,5-PENTACHLOROBIPHENYL (PCB 126) IN MULTIPLE ORGANS OF NORTHERN LEOPARD FROGS, RANA PIPIENS
Environmental Toxicology and Chemistry, vol. 20, no. 1, p. 191, 2001 - Acquired Resistance to Ah Receptor Agonists in a Population of Atlantic Killifish (Fundulus heteroclitus) Inhabiting a Marine Superfund Site: In Vivo and in Vitro Studies on the Inducibility of Xenobiotic Metabolizing Enzymes
Toxicological Sciences, vol. 60, no. 1, pp. 77–91, 2001 - Catalytic and immunochemical properties of hepatic cytochrome P450 1A in three avian species treated with ß-naphthoflavone or isosafrole
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, vol. 130, no. 1, pp. 67–83, 2001 - Nitric oxide synthase sequences in the marine fish Stenotomus chrysops and the sea urchin Arbacia punctulata, and phylogenetic analysis of nitric oxide synthase calmodulin-binding domains
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, vol. 130, no. 4, pp. 479–491, 2001 - Environmental Science & Technology, vol. 35, no. 1, pp. 54–62, 2001
- Induction and suppression of cytochrome P450 1A by 3,3',4,4',5-pentachlorobiphenyl and its relationship to oxidative stress in the marine fish scup (Stenotomus chrysops)
Aquatic Toxicology, vol. 52, no. 2, pp. 101–115, 2001 - 3,3',4,4'-Tetrachlorobiphenyl oxidation in fish, bird and reptile species: relationship to cytochrome P450 1A inactivation and reactive oxygen production
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, vol. 125, no. 3, pp. 273–286, 2000 - Cellular localization of CYP3A proteins in various tissues from pilot whale (Globicephala melas)
Environmental Toxicology and Pharmacology, vol. 8, no. 4, pp. 245–253, 2000 - Identification of NF-?B in the marine fish Stenotomus chrysops and examination of its activation by aryl hydrocarbon receptor agonists
Chemico-Biological Interactions, vol. 126, no. 2, pp. 137–157, 2000 - Induction of cytochrome P450 1A in the American Eel by model halogenated and non-halogenated aryl hydrocarbon receptor agonists
Aquatic Toxicology, vol. 50, no. 4, pp. 375–386, 2000 - In vitro metabolism of polychlorinated biphenyl congeners by beluga whale (Delphinapterus leucas) and pilot whale (Globicephala melas) and relationship to cytochrome P450 expression
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, vol. 126, no. 3, pp. 267–284, 2000 - Identification, Functional Characterization, and Regulation of a New Cytochrome P450 Subfamily, the CYP2Ns
Journal of Biological Chemistry, vol. 275, no. 4, pp. 2312–2321, 2000 - Serum Alters the Uptake and Relative Potencies of Halogenated Aromatic Hydrocarbons in Cell Culture Bioassays
Toxicological Sciences, vol. 53, no. 2, pp. 316–325, 2000 - Hepatic biotransformation enzymes in a sentinel species, the painted turtle ( Chrysemys picta ), from Cape Cod, Massachusetts: seasonal-, sex- and location related differences
Biomarkers, vol. 5, no. 5, pp. 382–394, 2000 - HEPATIC P4501A ACTIVITY, PLASMA SEX STEROIDS, AND GONADAL STEROIDOGENESIS IN VITRO IN YELLOW PERCH EXPOSED TO 3,3′,4,4′,5-PENTACHLOROBIPHENYL
Environmental Toxicology and Chemistry, vol. 19, no. 12, p. 3052, 2000 - Relative Contributions of Affinity and Intrinsic Efficacy to Aryl Hydrocarbon Receptor Ligand Potency
Toxicology and Applied Pharmacology, vol. 168, no. 2, pp. 160–172, 2000 - In Situ RT-PCR Detection of CYP1A mRNA in Pharyngeal Epithelium and Chondroid Cells from Chemically Untreated Fish: Involvement in Vertebrate Craniofacial Skeletal Development?
Biochemical and Biophysical Research Communications, vol. 271, no. 1, pp. 130–137, 2000 - BIOACCUMULATION PATTERNS OF POLYCHLORINATED BIPHENYLS AND CHLORINATED PESTICIDES IN NORTHWEST ATLANTIC PILOT WHALES
Environmental Toxicology and Chemistry, vol. 19, no. 3, p. 667, 2000 - ORGANOCHLORINE EXPOSURE AND BIOACCUMULATION IN THE ENDANGERED NORTHWEST ATLANTIC RIGHT WHALE (EUBALAENA GLACIALIS) POPULATION
Environmental Toxicology and Chemistry, vol. 19, no. 3, p. 654, 2000 - Time- and Concentration-Dependent Induction of CYP1A1 and CYP1A2 in Precision-Cut Rat Liver Slices Incubated in Dynamic Organ Culture in the Presence of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin,
Toxicology and Applied Pharmacology, vol. 155, no. 2, pp. 127–138, 1999 - Immunochemical Analysis of Liver Microsomal Cytochromes P450 of the American Alligator, Alligator mississippiensis
Toxicology and Applied Pharmacology, vol. 157, no. 3, pp. 157–165, 1999 - MOLECULAR STUDIES ON THE TOXIFYING EFFECTS BY GENETICALLY ENGINEERED CYTOCHROMES P450
Drug Metabolism Reviews, vol. 31, no. 2, pp. 423–435, 1999 - Species-dependent Metabolism of Benzo[c]phenanthrene and Dibenzo[a, l]pyrene by Various CYP450 Isoforms
Polycyclic Aromatic Compounds, vol. 16, no. 1, pp. 191–203, 1999 - Elevated levels of multiple cytochrome P450 forms in tilapia from Billings Reservoir-São Paulo, Brazil
Aquatic Toxicology, vol. 44, no. 4, pp. 289–305, 1999 - Altered CYP1A expression in Fundulus heteroclitus adults and larvae: a sign of pollutant resistance?
Aquatic Toxicology, vol. 45, no. 2-3, pp. 99–113, 1999 - Cytochromes P450 in liver of the turtle Chrysemys picta picta and the induction and partial purification of CYP1A-like proteins
Biochimica et Biophysica Acta (BBA) - General Subjects, vol. 1381, no. 1, pp. 12–26, 1998 - An evaluation of the relationships among oxidative stress, antioxidant vitamins and early mortality syndrome (EMS) of lake trout (Salvelinus namaycush) from Lake Ontario
Aquatic Toxicology, vol. 43, no. 2-3, pp. 195–208, 1998 - Aryl hydrocarbon receptor function in early vertebrates: Inducibility of cytochrome P450 1A in agnathan and elasmobranch fish
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, vol. 120, no. 1, pp. 67–75, 1998 - Editorial
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, vol. 121, no. 1-3, pp. 1–3, 1998 - Molecular cloning of CYP1A from the estuarine fish Fundulus heteroclitus and phylogenetic analysis of CYP1 genes: update with new sequences
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, vol. 121, no. 1-3, pp. 231–240, 1998 - Detection of CYP1A1 protein in human liver and induction by TCDD in precision-cut liver slices incubated in dynamic organ culture
Carcinogenesis, vol. 19, no. 8, pp. 1361–1368, 1998 - Effects of triphenyltin and other organotins on hepatic monooxygenase system in fish
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, vol. 121, no. 1-3, pp. 277–288, 1998 - Environmental contamination and developmental abnormalities in eggs and hatchlings of the common snapping turtle (Chelydra serpentina serpentina) from the Great Lakes?St Lawrence River basin (1989?1991)
Environmental Pollution, vol. 101, no. 1, pp. 143–156, 1998 - Cytochromes P-4501A, P-4503A and P-4502B in liver and heart of Mugil capito treated with CYP1A inducers
Environmental Toxicology and Pharmacology, vol. 6, no. 1, pp. 13–25, 1998 - Induction Time Course of Cytochromes P450 by Phenobarbital and 3-Methylcholanthrene Pretreatment in Liver Microsomes of Alligator mississippiensis
Biochemical Pharmacology, vol. 55, no. 9, pp. 1513–1521, 1998 - Correlation of 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Apoptotic Cell Death in the Embryonic Vasculature with Embryotoxicity
Toxicology and Applied Pharmacology, vol. 148, no. 1, pp. 24–34, 1998 - Arachidonic Acid Metabolism in the Marine FishStenotomus chrysops(Scup) and the Effects of Cytochrome P450 1A Inducers
Archives of Biochemistry and Biophysics, vol. 353, no. 2, pp. 265–275, 1998 - Glucocorticoid Potentiation of Cytochrome P4501A1 Induction by 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Porcine and Human Endothelial Cells in Culture
Biochemical and Biophysical Research Communications, vol. 232, no. 3, pp. 749–753, 1997 - Isolation of a Cytochrome P450 3A cDNA Sequence (CYP3A30) from the Marine TeleostFundulus heteroclitusand Phylogenetic Analyses ofCYP3AGenes
Biochemical and Biophysical Research Communications, vol. 236, no. 2, pp. 306–312, 1997 - Route-Specific Cellular Expression of Cytochrome P4501A (CYP1A) in Fish (Fundulus heteroclitus) Following Exposure to Aqueous and Dietary Benzo[a]pyrene
Toxicology and Applied Pharmacology, vol. 142, no. 2, pp. 348–359, 1997 - Correlation of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Induction of Cytochrome P4501A in Vascular Endothelium with Toxicity in Early Life Stages of Lake Trout,
Toxicology and Applied Pharmacology, vol. 143, no. 2, pp. 256–273, 1997 - Induction and post-transcriptional suppression of hepatic cytochrome p450 1a1 by 3,3',4,4'-tetrachlorobiphenyl
Biochemical Pharmacology, vol. 53, no. 7, pp. 1029–1040, 1997 - Cytochromes P450 (CYP) in Tropical Fishes: Catalytic Activities, Expression of Multiple CYP Proteins and High Levels of Microsomal P450 in Liver of Fishes From Bermuda
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, vol. 116, no. 1, pp. 61–75, 1997 - Environmental Science & Technology, vol. 31, no. 4, pp. 1198–1205, 1997
- Stages of hydropic vacuolation in the liver of winter flounder Pleuronectes americanus from a chemically contaminated site
Diseases of Aquatic Organisms, vol. 31, pp. 19–28, 1997 - GLUCOCORTICOID–XENOBIOTIC INTERACTIONS: DEXAMETHASONE-MEDIATED POTENTIATION OF CYTOCHROME P4501A INDUCTION BY β-NAPHTHOFLAVONE IN A FISH HEPATOMA CELL LINE (PLHC-1)
Environmental Toxicology and Chemistry, vol. 16, no. 5, p. 900, 1997 - RAPID ASSESSMENT OF INDUCED CYTOCHROME P4501A PROTEIN AND CATALYTIC ACTIVITY IN FISH HEPATOMA CELLS GROWN IN MULTIWELL PLATES: RESPONSE TO TCDD, TCDF, AND TWO PLANAR PCBS
Environmental Toxicology and Chemistry, vol. 15, no. 4, p. 582, 1996 - BIOLOGICAL EFFECTS OF POLYCHLORINATED DIBENZO-p-DIOXINS, DIBENZOFURANS, AND BIPHENYLS IN BALD EAGLE (HALIAEETUS LEUCOCEPHALUS) CHICKS
Environmental Toxicology and Chemistry, vol. 15, no. 5, p. 782, 1996 - P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature
Pharmacogenetics, vol. 6, no. 1, pp. 1–42, 1996 - Hepatocyte vacuolation and autolytic changes in the liver of pilot whales, Globicephala melas, stranded on Cape Cod, MA, USA
Science of The Total Environment, vol. 186, no. 1-2, pp. 105–108, 1996 - Cytochrome P4501A Induction in Avian Hepatocyte Cultures: A Promising Approach for Predicting the Sensitivity of Avian Species to Toxic Effects of Halogenated Aromatic Hydrocarbons
Toxicology and Applied Pharmacology, vol. 141, no. 1, pp. 214–230, 1996 - Immunochemical relationships of cytochrome P4503A-like proteins in teleost fish
Fish Physiology and Biochemistry, vol. 15, no. 4, pp. 323–332, 1996 - Cytochromes P450 (CYP) in thePoeciliopsis lucidaHepatocellular Carcinoma Cell Line (PLHC-1): Dose- and Time-Dependent Glucocorticoid Potentiation of CYP1A Induction without Induction of CYP3A
Archives of Biochemistry and Biophysics, vol. 329, no. 1, pp. 113–122, 1996 - Aminoanthracene Is a Mechanism-Based Inactivator of CYP1A in Channel Catfish Hepatic Tissue
Toxicology and Applied Pharmacology, vol. 135, no. 2, pp. 208–215, 1995 - SECOND-ROUND INTERLABORATORY COMPARISON OF HEPATIC ETHOXYRESORUFIN-O-DEETHYLASE ACTIVITY IN WHITE SUCKER (CATOSTOMUS COMMERSONI) EXPOSED TO BLEACHED-KRAFT PULP MILL EFFLUENT
Environmental Toxicology and Chemistry, vol. 14, no. 9, p. 1513, 1995 - INDUCTION OF CYTOCHROME P4501A IN THE MUMMICHOG (FUNDULUS HETEROCLITUS) BY THE POLYCHLORINATED TERPHENYL FORMULATION AROCLOR 5432
Environmental Toxicology and Chemistry, vol. 14, no. 3, p. 405, 1995 - Uptake of waterborne 3,3',4,4'-tetrachlorobiphenyl and organ and cell-specific induction of cytochrome P4501A in adult and larval fathead minnow Pimephales promelas
Aquatic Toxicology, vol. 28, no. 3-4, pp. 147–167, 1994 - Photoaffinity Labeling of the Ah Receptor: Phylogenetic Survey of Diverse Vertebrate and Invertebrate Species
Archives of Biochemistry and Biophysics, vol. 310, no. 1, pp. 218–228, 1994 - Catalytic and Immunochemical Characterization of Hepatic Microsomal Cytochromes P450 in Beluga Whale (Delphinapterus leucas)
Toxicology and Applied Pharmacology, vol. 126, no. 1, pp. 45–57, 1994 - Regulation of Cytochrome P4501A1 in Teleosts: Sustained Induction of CYP1A1 mRNA, Protein, and Catalytic Activity by 2,3,7,8-Tetrachlorodibenzofuran in the Marine Fish Stenotomus chrysops
Toxicology and Applied Pharmacology, vol. 127, no. 2, pp. 187–198, 1994 - Toxicological and ecological implications of biotransformation enzymes in the tropical teleost Chaetodon capistratus
Marine Biology, vol. 119, no. 1, pp. 151–158, 1994 - A cell proliferation assay for small fish and aquatic invertebrates using bath exposure to bromodeoxyuridine
Aquatic Toxicology, vol. 30, no. 2, pp. 183–188, 1994 - Polychlorinated biphenyl congener distributions in winter flounder as related to gender, spawning site, and congener metabolism
Environmental Science & Technology, vol. 28, no. 3, pp. 401–407, 1994 - INTERLABORATORY COMPARISON AND OPTIMIZATION OF HEPATIC MICROSOMAL ETHOXYRESORUFIN O-DEETHYLASE ACTIVITY IN WHITE SUCKER (CATOSTOMUS COMMERSONI) EXPOSED TO BLEACHED KRAFT PULP MILL EFFLUENT
Environmental Toxicology and Chemistry, vol. 12, no. 7, p. 1273, 1993 - Time-course and dose-response of the apparent induction of the cytochrome P450 monooxygenase system of pyloric caeca musomes of the female sea star L. by benzo[a]pyrene and polychlorinated biphenyls
Aquatic Toxicology, vol. 26, no. 1-2, pp. 23–39, 1993 - Effects of recombinant salmon growth hormone on hypophysectomized male Fundulus heteroclitus
Comparative Biochemistry and Physiology Part A: Physiology, vol. 106, no. 4, pp. 743–747, 1993 - Cytochrome P4501A induction and inhibition by 3,3',4,4'-tetrachlorobiphenyl in an Ah receptor-containing fish hepatoma cell line (PLHC-1)
Aquatic Toxicology, vol. 26, no. 3-4, pp. 185–208, 1993 - Effects of tributyltin in vivo on hepatic cytochrome P450 forms in marine fish
Aquatic Toxicology, vol. 24, no. 3-4, pp. 219–240, 1993 - A visual test for hepatic EROD activity as a marker for exposure to aromatic and halogenated aromatic hydrocarbons
Chemosphere, vol. 27, no. 11, pp. 2183–2195, 1993 - BIOMONITORING ENVIRONMENTAL CONTAMINATION WITH PIPPING BLACK-CROWNED NIGHT HERON EMBRYOS: INDUCTION OF CYTOCHROME P450
Environmental Toxicology and Chemistry, vol. 12, no. 9, p. 1719, 1993 - Phylogenetic distribution of the Ah receptor in non-mammalian species: implications for dioxin toxicity and Ah receptor evolution
Chemosphere, vol. 25, no. 7-10, pp. 931–937, 1992 - Effects of temperature acclimation on the expression of hepatic cytochrome P4501A mRNA and protein in the fish Fundulus heteroclitus*1
Archives of Biochemistry and Biophysics, vol. 299, no. 1, pp. 38–46, 1992 - Immunochemical cross-reactivity ofß-naphthoflavone-inducible cytochrome P450 (P450IA) in liver microsomes from different fish species and rat
Fish Physiology and Biochemistry, vol. 9, no. 1, pp. 1–13, 1991 - Sex differences in hepatic monooxygenases in winter flounder (Pseudopleuronectes americanus) and scup (Stenotomus chrysops) and regulation of P450 forms by estradiol
Journal of Experimental Zoology, vol. 259, no. 3, pp. 330–342, 1991 - Immunohistochemical localization of environmentally induced cytochrome P450IA1 in multiple organs of the marine teleost Stenotomus chrysops (scup)
Toxicology and Applied Pharmacology, vol. 110, no. 3, pp. 486–504, 1991 - CYTOCHROME P450E (P450IA) INDUCTION AND INHIBITION IN WINTER FLOUNDER BY 3,3′,4,4′-TETRACHLOROBIPHENYL: COMPARISON OF RESPONSE IN FISH FROM GEORGES BANK AND NARRAGANSETT BAY
Environmental Toxicology and Chemistry, vol. 10, no. 6, p. 765, 1991 - Mutations in c-Ki-Ras Oncogenes in Diseased Livers of Winter Flounder from Boston Harbor
Proceedings of the National Academy of Sciences, vol. 87, no. 2, pp. 841–845, 1990 - Feminization of the hepatic microsomal cytochrome P-450 system in brook trout by estradiol, testosterone, and pituitary factors
Journal of Experimental Zoology, vol. 253, no. 1, pp. 51–60, 1990 - Induced cytochrome P-450 in intestine and liver of spot (Leiostomus xanthurus) from a polycyclic aromatic hydrocarbon contaminated environment
Aquatic Toxicology, vol. 17, no. 2, pp. 119–131, 1990 - Experimental and environmental induction of cytochrome P450E in fish from Bermuda waters,
Journal of Experimental Marine Biology and Ecology, vol. 138, no. 1-2, pp. 49–67, 1990 - Cytochrome P-450E induction and localization in gill pillar (endothelial) cells of scup and rainbow trout
Aquatic Toxicology, vol. 14, no. 4, pp. 307–322, 1989 - The temporal relationships between P450E protein content, catalytic activity, and mRNA levels in the teleost Fundulus heteroclitus following treatment with ?-naphthoflavone*1
Archives of Biochemistry and Biophysics, vol. 268, no. 2, pp. 525–535, 1989 - Cloned rainbow trout liver P1450 complementary DNA as a potential environmental monitor
Toxicology and Applied Pharmacology, vol. 98, no. 2, pp. 362–368, 1989 - Effects of ortho- and non-ortho-substituted polychlorinated biphenyl congeners on the hepatic monooxygenase system in scup (Stenotomus chrysops)
Toxicology and Applied Pharmacology, vol. 98, no. 3, pp. 422–433, 1989 - Further consideration of phenobarbital effects on cytochrome P-450 activity in the killifish, Fundulus Heteroclitus
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, vol. 92, no. 2, pp. 223–230, 1989 - Regulation of gonadal steroidogenesis in Fundulus heteroclitus by recombinant salmon growth hormone and purified salmon prolactin
General and Comparative Endocrinology, vol. 72, no. 1, pp. 144–153, 1988 - Patterns and regulation of estradiol metabolism by hepatic microsomes from two species of marine teleosts*1
General and Comparative Endocrinology, vol. 66, no. 2, pp. 256–265, 1987 - Specificity and cross-reactivity of monoclonal and polyclonal antibodies against cytochrome -450E of the marine fish scup
Archives of Biochemistry and Biophysics, vol. 253, no. 1, pp. 268–278, 1987 - Cytochrome P-450 isozymes from the marine teleost Stenotomus chrysops: Their roles in steroid hydroxylation and the influence of cytochrome b5*1
Archives of Biochemistry and Biophysics, vol. 249, no. 2, pp. 326–338, 1986 - Benzo[a]pyrene oxidation and microsomal enzyme activity in the mussel (Mytilus edulis) and other bivalve mollusc species from the Western North Atlantic
Marine Biology, vol. 89, no. 1, pp. 21–30, 1985 - Induction of cytochrome -450-dependentmonooxygenase systems in embryos and eleutheroembryos of the killfish
Chemico-Biological Interactions, vol. 55, pp. 185–202, 1985 - An alternative 7-ethoxyresorufin -deethylase activity assay: A continuous visible spectrophotometric method for measurement of cytochrome -450 monooxygenase activity
Analytical Biochemistry, vol. 140, no. 1, pp. 138–145, 1984 - Microsomal electron transport and xenobiotic monooxygenase activities during the embryonic period of development in the killifish, Fundulus heteroclitus*1
Toxicology and Applied Pharmacology, vol. 73, no. 3, pp. 432–443, 1984 - Basal levels and induction of hepatic aryl hydrocarbon hydroxylase activity during the embryonic period of development in brook trout
Biochemical Pharmacology, vol. 32, no. 7, pp. 1324–1327, 1983 - An