David Dombrowicz was trained as a biologist and as a botanist and obtained his Ph.D. degree in endocrinology in 1991 from the University of Liege, Liege, Belgium. During his postdoctoral fellowship at NIH, NIAID, Bethesda, MD, USA in Dr Jean-Pierre Kinet laboratory, he performed the first inactivation of the alpha and beta subunits of the high affinity IgE receptor Fc-epsilon-RI and studied the role of this receptor as well as FcgammaRIII/CD16 in anaphylactic reactions. In 1996, he joined, at the Institut Pasteur de Lille, Lille, France, the INSERM Unit led by Professor Andre Capron. Together with Professor Monique Capron, he further investigated the role of Fc receptors, in particular their expression and function on eosinophils and in allergic and inflammatory diseases (asthma, atopic dermatitis, and colitis). He later studied the immunoregulatory properties of prostaglandin D2 and nuclear receptors in particular peroxisome proliferator activated receptors (PPARs). Since 2005, he has been the Research Director from INSERM. In 2010, he joined the INSERM Unit led by Bart Staels, at the Institut Pasteur de Lille to lead a team working on nuclear receptors and immunometabolism. In 1999, he received the award from the Pharmacia Allergy Research Foundation.
Biography Updated on 2 April 2013