Joanne Edwards holds a Ph.D. degree. She is a Senior Lecturer at the Institute of Cancer, University of Glasgow, with a cancer research team of 15 consisting of Ph.D. students, scientists, and clinical research fellows. Her main interests are identifying clinically relevant aberrations in breast and prostate cancer and establishing if they can be employed in clinical practise to improve patient care and outcome. She has established large clinical cohorts of both breast and prostate cancer tissue microarrays linked to databases with full clinical follow-up to identify which biomarkers have prognostic significance and therefore identify potential therapeutic targets. This approach has confirmed members of the Src family, IKK family, PI3K pathway, and MAPK pathway as potential therapeutic targets. In parallel to the clinical investigations, target validation is also performed in cell studies to establish the functional significance and relevance of activating and inhibiting these targets. The success of this twined tissue and cell line approach has resulted in over 80 peer-reviewed publications.
Biography Updated on 30 January 2012