Heinz D. Osiewacz

Institute of Molecular Biosciences;Johann Wolfgang Goethe University, Germany 0000-0002-0360-6994

Heinz D. Osiewacz received his Ph.D. degree at the University of Bochum, Germany, in 1984. From 1984 to 1985, he worked at the Plant Research Laboratory at Michigan State University, East Lansing, and returned to Bochum where he was a Research Assistant till 1990. From 1990 to 1994, he was the Head of the Molecular Biology of Aging Processes Department at the German Cancer Research Center (DKFZ), Heidelberg. Since 1994, he has been a Full Professor at the J.W. Goethe University of Frankfurt leading a research group on molecular developmental biology and a member of the cluster of excellence macromolecular complexes and in the Center of Membrane Proteomics. Osiewacz has a long-standing experience in the field of experimental gerontology. In 1985, he received the Sandoz Prize of Gerontology (together with K. Esser, U. Kück, U. Stahl, P. Tudzynski) by the International Association of Gerontology and in 2001 the Rene-Schubert Prize for Gerontology by the German Society of Gerontology for his work on aging. His scientific interests are in the field of aging research to unravel the molecular network of pathways controlling aging at the organism level. In particular, mitochondrial/nuclear interactions (cross-talks), mitochondrial DNA instabilities and mtDNA repair, respiration, retrograde signaling, ROS generation and scavenging, apoptosis, mitochondrial dynamics, and protein quality control at the genetic, biochemical, cytological, and physiological level are the focus of his work. His recent interest turned toward the understanding of organism aging in a holistic sense using systems biology approaches. Moreover, Osiewacz edited or coedited three books on aging research and published 120 research papers, reviews, or book chapters. He was or is a coordinator (MiMage) and a partner of different European projects. Since 2010, he has coordinated national-integrated research projects on aging and a national consortium on systems biology and ageing (GerontoMitoSys).

Biography Updated on 15 December 2011

Scholarly Contributions [Data Provided by scopus]