John T. Isaac

Articles in Scholarly Journals [Incomplete List]

  1. Developmental synaptic plasticity at the thalamocortical input to barrel cortex: Mechanisms and roles
    Molecular and Cellular Neuroscience, vol. 34, no. 4, pp. 493–502, 2007
  2. LTP Inhibits LTD in the Hippocampus via Regulation of GSK3ß
    Neuron, vol. 53, no. 5, pp. 703–717, 2007
  3. The Role of the GluR2 Subunit in AMPA Receptor Function and Synaptic Plasticity
    Neuron, vol. 54, no. 6, pp. 859–871, 2007
  4. Synaptic strength at the thalamocortical input to layer IV neonatal barrel cortex is regulated by protein kinase C
    Neuropharmacology, vol. 52, no. 1, pp. 185–192, 2007
  5. Coordinated developmental recruitment of latent fast spiking interneurons in layer IV barrel cortex
    Nature Neuroscience, Article ID nn1866, 2007
  6. Long-Term Depression of Kainate Receptor-Mediated Synaptic Transmission
    Neuron, vol. 49, no. 1, pp. 95–106, 2006
  7. Functional Maturation of CA1 Synapses Involves Activity-Dependent Loss of Tonic Kainate Receptor-Mediated Inhibition of Glutamate Release
    Neuron, vol. 50, no. 3, pp. 415–429, 2006
  8. Regulation of NR1/NR2C N-Methyl-D-aspartate (NMDA) Receptors by Phosphorylation
    Journal of Biological Chemistry, vol. 281, no. 24, pp. 16583–16590, 2006
  9. Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation
    Nature Neuroscience, vol. 9, no. 5, Article ID nn1678, 2 pages, 2006
  10. Molecular Pain, vol. 2, no. 1, p. 38, 2006
  11. Rapid, Activity-Dependent Plasticity in Timing Precision in Neonatal Barrel Cortex
    Journal of Neuroscience, vol. 26, no. 16, pp. 4178–4187, 2006
  12. Identification of an Endoplasmic Reticulum-Retention Motif in an Intracellular Loop of the Kainate Receptor Subunit KA2
    Journal of Neuroscience, vol. 26, no. 26, pp. 7014–7021, 2006
  13. Developmental Changes in AMPA and Kainate Receptor-Mediated Quantal Transmission at Thalamocortical Synapses in the Barrel Cortex
    Journal of Neuroscience, vol. 25, no. 21, pp. 5259–5271, 2005
  14. Endogenous Activation of Kainate Receptors Regulates Glutamate Release and Network Activity in the Developing Hippocampus
    Journal of Neuroscience, vol. 25, no. 18, pp. 4473–4484, 2005
  15. Protein Kinase C Phosphorylation of the Metabotropic Glutamate Receptor mGluR5 on Serine 839 Regulates Ca2+ Oscillations
    Journal of Biological Chemistry, vol. 280, no. 27, pp. 25409–25415, 2005
  16. Profound regulation of neonatal CA1 rat hippocampal GABAergic transmission by functionally distinct kainate receptor populations
    The Journal of Physiology, vol. 567, no. 1, pp. 131–142, 2005
  17. ATP hydrolysis is required for the rapid regulation of AMPA receptors during basal synaptic transmission and long-term synaptic plasticity
    Neuropharmacology, vol. 48, no. 7, pp. 949–955, 2005
  18. Hippocalcin Functions as a Calcium Sensor in Hippocampal LTD
    Neuron, vol. 47, no. 4, pp. 487–494, 2005
  19. Kainate receptor trafficking: physiological roles and molecular mechanisms
    Pharmacology & Therapeutics, vol. 104, no. 3, pp. 163–172, 2004
  20. Receptor trafficking and synaptic plasticity
    Nature Reviews Neuroscience, vol. 5, no. 12, Article ID nrn1556, 10 pages, 2004
  21. BMC Neuroscience, vol. 5, no. 1, p. 44, 2004
  22. Multiple, Developmentally Regulated Expression Mechanisms of Long-Term Potentiation at CA1 Synapses
    Journal of Neuroscience, vol. 24, no. 21, pp. 4903–4911, 2004
  23. Regulation of Synaptic Strength and AMPA Receptor Subunit Composition by PICK1
    Journal of Neuroscience, vol. 24, no. 23, pp. 5381–5390, 2004
  24. GluR2 protein-protein interactions and the regulation of AMPA receptors during synaptic plasticity
    Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 358, no. 1432, pp. 715–720, 2003
  25. Kainate receptors and the induction of mossy fibre long-term potentiation
    Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 358, no. 1432, pp. 657–666, 2003
  26. Postsynaptic silent synapses: evidence and mechanisms
    Neuropharmacology, vol. 45, no. 4, pp. 450–460, 2003
  27. Trafficking and surface expression of the glutamate receptor subunit, KA2
    Biochemical and Biophysical Research Communications, vol. 310, no. 1, pp. 8–13, 2003
  28. Functional roles of protein interactions with AMPA and kainate receptors
    Neuroscience Research, vol. 47, no. 1, pp. 3–15, 2003
  29. Rapid and Differential Regulation of AMPA and Kainate Receptors at Hippocampal Mossy Fibre Synapses by PICK1 and GRIP
    Neuron, vol. 37, no. 4, pp. 625–638, 2003
  30. Neuron, vol. 38, no. 4, p. 673, 2003
  31. A Role for Ca2+ Stores in Kainate Receptor-Dependent Synaptic Facilitation and LTP at Mossy Fiber Synapses in the Hippocampus
    Neuron, vol. 39, no. 2, pp. 327–341, 2003
  32. Phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression
    Nature Neuroscience, vol. 5, no. 9, Article ID nn903, 1 pages, 2002
  33. A Presynaptic Kainate Receptor Is Involved in Regulating the Dynamic Properties of Thalamocortical Synapses during Development
    Neuron, vol. 34, no. 4, pp. 635–646, 2002
  34. Developmental and Activity Dependent Regulation of Ionotropic Glutamate Receptors at Synapses
    TheScientificWorldJOURNAL, vol. 2, pp. 27–47, 2002
  35. Mathematical modelling of non-stationary fluctuation analysis for studying channel properties of synaptic AMPA receptors
    The Journal of Physiology, vol. 537, no. 2, pp. 407–420, 2001
  36. A Critical Role of a Facilitatory Presynaptic Kainate Receptor in Mossy Fiber LTP
    Neuron, vol. 32, no. 4, pp. 697–709, 2001
  37. Protein Phosphatase 1 and LTDSynapses Are the Architects of Depression
    Neuron, vol. 32, no. 6, pp. 963–966, 2001
  38. Synaptic activation of a presynaptic kainate receptor facilitates AMPA receptor-mediated synaptic transmission at hippocampal mossy fibre synapses.
    Neuropharmacology, vol. 41, no. 8, pp. 907–915, 2001
  39. PDZ Proteins Interacting with C-Terminal GluR2/3 Are Involved in a PKC-Dependent Regulation of AMPA Receptors at Hippocampal Synapses
    Neuron, vol. 28, no. 3, pp. 873–886, 2000
  40. Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex
    Neuropharmacology, vol. 39, no. 5, pp. 725–732, 2000
  41. Hippocampal LTD Expression Involves a Pool of AMPARs Regulated by the NSF?GluR2 Interaction
    Neuron, vol. 24, no. 2, pp. 389–399, 1999
  42. Nature, vol. 400, no. 6744, pp. 569–573, 1999
  43. Nature Neuroscience, vol. 2, no. 4, pp. 297–299, 1999
  44. Silent glutamatergic synapses in the mammalian brain
    Canadian Journal of Physiology and Pharmacology, vol. 77, no. 9, pp. 735–737, 1999
  45. Nature Neuroscience, vol. 1, no. 5, pp. 389–394, 1998
  46. Nature, vol. 393, no. 6687, pp. 793–797, 1998
  47. NSF Binding to GluR2 Regulates Synaptic Transmission
    Neuron, vol. 21, no. 1, pp. 87–97, 1998
  48. Long-Term Depression at Thalamocortical Synapses in Developing Rat Somatosensory Cortex
    Neuron, vol. 21, no. 2, pp. 347–357, 1998
  49. An investigation of the expression mechanism of LTP of AMPA receptor-mediated synaptic transmission at hippocampal CA1 synapses using failures analysis and dendritic recordings
    Neuropharmacology, vol. 37, no. 10-11, pp. 1399–1410, 1998
  50. Silent Synapses during Development of Thalamocortical Inputs
    Neuron, vol. 18, no. 2, pp. 269–280, 1997
  51. Expression mechanisms of long-term potentiation in the hippocampus
    Journal of Physiology-Paris, vol. 90, no. 5-6, pp. 299–303, 1996
  52. Evidence for silent synapses: Implications for the expression of LTP
    Neuron, vol. 15, no. 2, pp. 427–434, 1995
  53. The local anaesthetic QX-314 enables enhanced whole-cell recordings of excitatory synaptic currents in rat hippocampal slices in vitro
    Neuroscience Letters, vol. 150, no. 2, pp. 227–230, 1993