J. Girard

Articles in Scholarly Journals [Incomplete List]

  1. Insulin regulation of glucokinase gene expression: Evidence against a role for sterol regulatory element binding protein 1 in primary hepatocytes
    FEBS Letters, vol. 580, no. 2, pp. 410–414, 2006
  2. Insulin's effect on the liver: "Direct or indirect?" continues to be the question
    Journal of Clinical Investigation, vol. 116, no. 2, pp. 302–304, 2006
  3. Liver-Specific Inhibition of ChREBP Improves Hepatic Steatosis and Insulin Resistance in ob/ob Mice
    Diabetes, vol. 55, no. 8, pp. 2159–2170, 2006
  4. The Inhibitory Effects of Insulin on Hepatic Glucose Production Are Both Direct and Indirect
    Diabetes, vol. 55, no. Supplement_2, pp. S65–S69, 2006
  5. Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation
    Journal of Clinical Investigation, vol. 115, no. 10, pp. 2843–2854, 2005
  6. Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage
    Journal of Clinical Investigation, vol. 115, no. 12, pp. 3554–3563, 2005
  7. Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver
    Biochimie, vol. 87, no. 1, pp. 81–86, 2005
  8. Identification of a novel rat hepatic gene induced early by insulin, independently of glucose
    Biochemical Journal, vol. 385, no. 1, p. 165, 2005
  9. Demonstration of N- and C-terminal domain intramolecular interactions in rat liver carnitine palmitoyltransferase 1 that determine its degree of malonyl-CoA sensitivity
    Biochemical Journal, vol. 387, no. 1, p. 67, 2005
  10. Hepatic Glucokinase Is Required for the Synergistic Action of ChREBP and SREBP-1c on Glycolytic and Lipogenic Gene Expression
    Journal of Biological Chemistry, vol. 279, no. 19, pp. 20314–20326, 2004
  11. Increased adipose tissue expression of Grb14 in several models of insulin resistance
    The FASEB Journal, 2004
  12. Glucose induces de novo lipogenesis in rat muscle satellite cells through a sterol-regulatory-element-binding-protein-1c-dependent pathway
    Journal of Cell Science, vol. 117, no. 10, pp. 1937–1944, 2004
  13. Cellular and Molecular Mechanisms of Adipose Tissue Plasticity in Muscle Insulin Receptor Knockout Mice
    Endocrinology, vol. 145, no. 4, pp. 1926–1932, 2003
  14. Functional and Structural Basis of Carnitine Palmitoyltransferase 1A Deficiency
    Journal of Biological Chemistry, vol. 278, no. 50, pp. 50428–50434, 2003
  15. Inhibition of Insulin Receptor Catalytic Activity by the Molecular Adapter Grb14
    Journal of Biological Chemistry, vol. 277, no. 7, pp. 4845–4852, 2002
  16. The Coactivator PGC-1 Is Involved in the Regulation of the Liver Carnitine Palmitoyltransferase I Gene Expression by cAMP in Combination with HNF4alpha and cAMP-response Element-binding Protein (CREB)
    Journal of Biological Chemistry, vol. 277, no. 41, pp. 37991–38000, 2002
  17. The Extreme C Terminus of Rat Liver Carnitine Palmitoyltransferase I Is Not Involved in Malonyl-CoA Sensitivity but in Initial Protein Folding
    Journal of Biological Chemistry, vol. 277, no. 49, pp. 47184–47189, 2002
  18. The Adapter Protein ZIP Binds Grb14 and Regulates Its Inhibitory Action on Insulin Signaling by Recruiting Protein Kinase Czeta
    Molecular and Cellular Biology, vol. 22, no. 20, pp. 6959–6970, 2002
  19. Organization of the human liver carnitine palmitoyltransferase 1 gene ( CPT1A ) and identification of novel mutations in hypoketotic hypoglycaemia
    Human Genetics, vol. 111, no. 2, pp. 179–189, 2002
  20. Sterol Regulatory Element Binding Protein-1c Expression and Action in Rat Muscles: Insulin-Like Effects on the Control of Glycolytic and Lipogenic Enzymes and UCP3 Gene Expression
    Diabetes, vol. 51, no. 6, pp. 1722–1728, 2002
  21. Mutations in the Human Leptin and Leptin Receptor Genes as Models of Serum Leptin Receptor Regulation
    Diabetes, vol. 51, no. 6, pp. 1980–1985, 2002
  22. Effects of Benfluorex on Fatty Acid and Glucose Metabolism in Isolated Rat Hepatocytes: From Metabolic Fluxes to Gene Expression
    Diabetes, vol. 51, no. 8, pp. 2363–2368, 2002
  23. Molecular and Enzymatic Characterization of a Unique Carnitine Palmitoyltransferase 1A Mutation in the Hutterite Community
    Molecular Genetics and Metabolism, vol. 73, no. 1, pp. 46–54, 2001
  24. Effect of metformin on fatty acid and glucose metabolism in freshly isolated hepatocytes and on specific gene expression in cultured hepatocytes
    Biochemical Pharmacology, vol. 62, no. 4, pp. 439–446, 2001
  25. Dissociation between Insulin-Mediated Signaling Pathways and Biological Effects in Placental Cells: Role of Protein Kinase B and MAPK Phosphorylation
    Endocrinology, vol. 142, no. 9, pp. 3974–3979, 2001
  26. The N-terminal Domain of Rat Liver Carnitine Palmitoyltransferase 1 Contains an Internal Mitochondrial Import Signal and Residues Essential for Folding of Its C-terminal Catalytic Domain
    Journal of Biological Chemistry, vol. 276, no. 7, pp. 5403–5411, 2001
  27. Long-chain fatty acids regulate liver carnitine palmitoyltransferase I gene (L-CPT I) expression through a peroxisome-proliferator-activated receptor a (PPARa)-independent pathway
    Biochemical Journal, vol. 354, no. 1, p. 189, 2001
  28. A Novel Cytosolic Dual Specificity Phosphatase, Interacting with Glucokinase, Increases Glucose Phosphorylation Rate
    Journal of Biological Chemistry, vol. 275, no. 42, pp. 32406–32412, 2000
  29. Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2
    Oncogene, vol. 19, no. 16, pp. 2052–2059, 2000
  30. Stat 5B, Activated by Insulin in a Jak-Independent Fashion, Plays a Role in Glucokinase Gene Transcription
    Endocrinology, vol. 141, no. 6, pp. 1977–1988, 2000
  31. Comparative in Vivo Approaches for Selective Adenovirus-Mediated Gene Delivery to the Placenta
    Human Gene Therapy, vol. 11, no. 1, pp. 167–177, 2000
  32. Reduced hepatic fatty acid oxidation in fasting PPARa null mice is due to impaired mitochondrial hydroxymethylglutaryl-CoA synthase gene expression
    FEBS Letters, vol. 475, no. 3, pp. 163–166, 2000
  33. Structural and Functional Characterizations of the 5'-Flanking Region of the Mouse Glucagon Receptor Gene: Comparison with the Rat Gene
    Biochemical and Biophysical Research Communications, vol. 272, no. 3, pp. 912–921, 2000
  34. Macrosomia revisited: Ponderal index and leptin delineate subtypes of fetal overgrowth
    American Journal of Obstetrics and Gynecology, vol. 181, no. 3, pp. 621–625, 1999
  35. Treatment of streptozotocin-induced diabetic rats with vanadate and phlorizin prevents the over-expression of the liver insulin receptor gene
    European Journal of Endocrinology, vol. 140, no. 1, pp. 79–86, 1999
  36. Overexpression of placental leptin in diabetic pregnancy: a critical role for insulin
    Diabetes, vol. 47, no. 5, pp. 847–850, 1998
  37. Development and regulation of glucose-6-phosphatase gene expression in rat liver, intestine, and kidney: in vivo and in vitro studies in cultured fetal hepatocytes
    Diabetes, vol. 47, no. 6, pp. 882–889, 1998
  38. Unexpected Expression of Glucose Transporter 4 in Villous Stromal Cells of Human Placenta
    Journal of Clinical Endocrinology & Metabolism, vol. 83, no. 11, pp. 4097–4101, 1998
  39. Topological and functional analysis of the rat liver carnitine palmitoyltransferase 1 expressed in Saccharomyces cerevisiae
    FEBS Letters, vol. 429, no. 2, pp. 173–178, 1998
  40. Hexokinase isoenzymes in the rat placenta
    Placenta, vol. 19, no. 5-6, pp. 439–442, 1998
  41. Longitudinal study of tissue- and subunit-specific obesity-induced regulation of the pyruvate dehydrogenase complex
    Molecular and Cellular Endocrinology, vol. 144, no. 1-2, pp. 139–147, 1998
  42. Current Opinion in Clinical Nutrition & Metabolic Care, vol. 1, no. 4, pp. 323–328, 1998
  43. In Vivo and in Vitro Regulation of Hepatic Glucagon Receptor mRNA Concentration by Glucose Metabolism
    Journal of Biological Chemistry, vol. 273, no. 14, pp. 8088–8093, 1998
  44. Identification of the Rat Adapter Grb14 as an Inhibitor of Insulin Actions
    Journal of Biological Chemistry, vol. 273, no. 40, pp. 26026–26035, 1998
  45. An Unusual High-Km Hexokinase Is Expressed in the mhAT3F Hepatoma Cell Line
    Journal of Biological Chemistry, vol. 273, no. 40, pp. 26187–26193, 1998
  46. The N-terminal Domain of Rat Liver Carnitine Palmitoyltransferase 1 Mediates Import into the Outer Mitochondrial Membrane and Is Essential for Activity and Malonyl-CoA Sensitivity
    Journal of Biological Chemistry, vol. 273, no. 45, pp. 29896–29904, 1998
  47. Regulation of liver gene expression by glucose
    Proceedings of the Nutrition Society, vol. 57, no. 2, pp. 265–275, 1998
  48. MECHANISMS BY WHICH CARBOHYDRATES REGULATE EXPRESSION OF GENES FOR GLYCOLYTIC AND LIPOGENIC ENZYMES
    Annual Review of Nutrition, vol. 17, no. 1, pp. 325–352, 1997
  49. The GLUT3 Glucose Transporter Isoform Is Differentially Expressed within Human Placental Cell Types
    Journal of Clinical Endocrinology & Metabolism, vol. 82, no. 8, pp. 2689–2694, 1997
  50. Route of nutrient delivery influences liver lipidmetabolism in rats
    Clinical Nutrition, vol. 16, no. 3, pp. 149–149, 1997
  51. Effects of triiodothyronine and retinoic acid on glucokinase gene expression in neonatal rat hepatocytes
    Molecular and Cellular Endocrinology, vol. 130, no. 1-2, pp. 61–67, 1997
  52. Identification and Localization of a Skeletal Muscle Secrotonin 5-HT2A Receptor Coupled to the Jak/STAT Pathway
    Journal of Biological Chemistry, vol. 272, no. 23, pp. 14825–14829, 1997
  53. Evidence for a Direct Interaction between Insulin Receptor Substrate-1 and Shc
    Journal of Biological Chemistry, vol. 272, no. 27, pp. 17166–17170, 1997
  54. Variable Expression of Hepatic Glucokinase in Mice Is Due to a Regulational Locus That Cosegregates with the Glucokinase Gene,
    Genomics, vol. 45, no. 1, pp. 185–193, 1997
  55. The role of non-esterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects: results of the Paris Prospective Study
    Diabetologia, vol. 40, no. 9, pp. 1101–1106, 1997
  56. Normalization of insulin secretion by a selective alpha 2-adrenoceptor antagonist restores GLUT-4 glucose transporter expression in adipose tissue of type II diabetic rats
    Endocrinology, vol. 137, no. 5, pp. 2022–2027, 1996
  57. Excessive glucose production, rather than insulin resistance, accounts for hyperglycaemia in recent-onset streptozotocin-diabetic rats
    Diabetologia, vol. 38, no. 3, pp. 283–290, 1995
  58. Cloning and Characterization of the Mouse Glucokinase Gene Locus and Identification of Distal Liver-Specific DNase I Hypersensitive Sites
    Genomics, vol. 29, no. 3, pp. 740–750, 1995
  59. Transient increase in obese gene expression after food intake or insulin administration
    Nature, vol. 377, no. 6549, Article ID 377527a0, 1 pages, 1995
  60. Developmental expression of Glut1 glucose transporter and c-fos genes in human placental cells
    Placenta, vol. 15, no. 1, pp. 35–46, 1994
  61. Tissue-specific correction of lipogenic enzyme gene expression in diabetic rats given vanadate
    Diabetologia, vol. 37, no. 11, pp. 1065–1072, 1994
  62. Phlorizin treatment of diabetic rats partially reverses the abnormal expression of genes involved in hepatic glucose metabolism
    Diabetologia, vol. 36, no. 4, pp. 292–298, 1993
  63. A top-down control analysis in isolated rat liver mitochondria: can the 3-hydroxy-3-methylglutaryl-CoA pathway be rate-controlling for ketogenesis?
    Biochimica et Biophysica Acta (BBA) - General Subjects, vol. 1156, no. 2, pp. 135–143, 1993
  64. Glucose administration induces the premature expression of liver glucokinase gene in newborn rats. Relation with DNase-I-hypersensitive sites
    European Journal of Biochemistry, vol. 215, no. 3, pp. 883–892, 1993
  65. Influence of the weaning diet on the changes of glucose metabolism and of insulin sensitivity
    Proceedings of the Nutrition Society, vol. 52, no. 2, pp. 325–333, 1993
  66. Influence of diet on the development and regulation of lipogenic enzymes in adipose tissue
    Proceedings of the Nutrition Society, vol. 51, no. 3, pp. 387–395, 1992
  67. Effect of diets rich in medium-chain and long-chain triglycerides on lipogenic-enzyme gene expression in liver and adipose tissue of the weaned rat
    European Journal of Biochemistry, vol. 208, no. 2, pp. 381–387, 1992
  68. Hormonal control of specific gene expression in the rat liver during the suckling-weaning transition
    Advances in Enzyme Regulation, vol. 30, pp. 91–108, 1990
  69. Octanoate metabolism in isolated hepatocytes and mitochondria from fetal, newborn and adult rabbit. Evidence for a high capacity for octanoate esterification in term fetal liver
    European Journal of Biochemistry, vol. 184, no. 3, pp. 681–686, 1989
  70. Intramitochondrial factors controlling hepatic fatty acid oxidation at weaning in the rat
    FEBS Letters, vol. 232, no. 1, pp. 156–158, 1988
  71. Effect of feeding pattern on the sensitivity of hepatic carnitine palmitoyl-transferase to inhibition by malonyl-CoA in the rat
    Comparative Biochemistry and Physiology Part A: Physiology, vol. 87, no. 4, pp. 1041–1043, 1987
  72. Effects of insulin and norepinephrine on glucose transport and metabolism in rat brown adipocytes. Potentiation by insulin of norepinephrine-induced glucose oxidation
    European Journal of Biochemistry, vol. 170, no. 1-2, pp. 469–474, 1987
  73. Effect of lactation on insulin sensitivity of glucose metabolism in rat adipocytes
    FEBS Letters, vol. 194, no. 2, pp. 292–296, 1986
  74. Hyperglycaemia induced by glucose infusion in the unrestrained pregnant rat: Effect on body weight and lipid synthesis in post-mature fetuses
    Diabetologia, vol. 24, no. 2, pp. 128–130, 1983
  75. An Experimental model of phenformin-induced lactic acidosis in rats
    Diabetologia, vol. 14, no. 4, pp. 261–267, 1978
  76. The metabolic effects of sodium dichloroacetate in the suckling newborn rat
    Diabetologia, vol. 15, no. 6, pp. 459–463, 1978
  77. Effects of exogenous hormones and glucose on plasma levels and hepatic metabolism of amino acids in the fetus and in the newborn rat
    Diabetologia, vol. 12, no. 4, pp. 327–337, 1976