Stephen Tobe
Stephen Tobe received his undergraduate degree in biology from Queen’s University, Kingston, Canada, in 1967, his M.S. degree from the Department of Biology, York University, in 1969, and his Ph.D. degree in parasitology from McGill University in 1972. He was a postdoctoral Fellow during 1972–1974 at the Unit of Invertebrate Chemistry and Physiology, Agricultural Research Council, and a Research Fellow at the University of Sussex, UK. He joined the Department of Zoology at the University of Toronto in 1974 as an Assistant Professor and became a Full Professor in 1982. His laboratory works on aspects of the comparative endocrinology of invertebrates, particularly in insects (cockroaches and drosophila) and crustaceans (shrimp, crayfish, and lobster). Tobe was awarded the C. Gordon Hewitt Award by the Entomological Society of Canada in 1982, and the E.W.R. Steacie Fellowship by the National Research Council of Canada (1982–1984). He became a Fellow of the Royal Society of Canada (FRSC) in 1987. In 1988, he delivered the Opening Plenary Lecture at the International Congress of Entomology, Vancouver, and in 1990, he received the Gold Medal of the Entomological Society of Canada. Tobe was awarded the Pickford Medal in Comparative Endocrinology by the International Federation of Comparative Endocrinological Societies in 1993. He is an ISI Highly Cited Researcher in plant and animal science. He was a Group Leader of “Insect Biotech Canada,” a national network of Centers of Excellence, during 1990–1994, and was a Scientific Director of the network from 1994 to 2000. He has served as an Associate Dean of Science at the Faculty of Arts and Science (1988–1994) and as a Vice Dean from 1995 to 1996. Tobe presently serves on the Editorial Boards of the Journal of Insect Physiology, General and Comparative Endocrinology, and Physiological Entomology. He has also served as a Guest Editor of Insect Biochemistry (1987) and Journal of Insect Physiology (2004–2005).
Biography Updated on 25 April 2008
Personal Home Page
http://www.zoo.utoronto.ca/tobeweb/
Articles in Scholarly Journals [Incomplete List]
- The role of neuropeptides in caterpillar nutritional ecology
Peptides, vol. 28, no. 1, pp. 185–196, 2007 - Comparative genomic analysis of allatostatin-encoding (Ast) genes in Drosophila species and prediction of regulatory elements by phylogenetic footprinting
Peptides, vol. 28, no. 1, pp. 83–93, 2007 - Evolutionary selective trends of insect/mosquito antimicrobial defensin peptides containing cysteine-stabilized a/ß motifs
Peptides, vol. 28, no. 1, pp. 62–75, 2007 - The Role of Allatostatins in Juvenile Hormone Synthesis in Insects and Crustaceans
Annual Review of Entomology, vol. 52, no. 1, pp. 277–299, 2007 - Proctolin: A possible releasing factor in the corpus cardiacum/corpus allatum of the locust
Peptides, vol. 27, no. 3, pp. 559–566, 2006 - Bioinformatic analysis of neuropeptide and receptor expression profiles during midgut metamorphosis in Drosophila melanogaster
Peptides, vol. 27, no. 3, pp. 583–589, 2006 - Hemolymph clotting in crustaceans: Implications for neuropeptide extraction from invertebrate hemolymph
Peptides, vol. 27, no. 3, pp. 590–596, 2006 - Characterization of vitellogenin in the shrimpMetapenaeus ensis: Expression studies and hormonal regulation ofMeVg1 transcription in vitro
Molecular Reproduction and Development, vol. 73, no. 4, pp. 424–436, 2006 - A study of signal transduction for the two diuretic peptides of
Peptides, vol. 26, no. 1, pp. 89–98, 2005 - Immunocytochemical analysis of putative allatostatin receptor (DAR-2) distribution in the CNS of larval
Peptides, vol. 26, no. 1, pp. 81–87, 2005 - Effects of allatotropin and localization of allatotropin-immunoreactive cells in earwigs
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, vol. 142, no. 1, pp. 113–122, 2005 - Phe-Gly-Leu-amide allatostatin in the termite : Content in brain and corpus allatum and effect on juvenile hormone synthesis
Journal of Insect Physiology, vol. 51, no. 4, pp. 357–365, 2005 - Regulation of methyl farnesoate production by mandibular organs in the crayfish, : A possible role for allatostatins
Journal of Insect Physiology, vol. 51, no. 4, pp. 367–378, 2005 - JH8: Recent progress in juvenile hormone research
Journal of Insect Physiology, vol. 51, no. 4, pp. 343–343, 2005 - Purification and characterization of a mandibular organ protein from the American lobster, Homarus americanus: a putative farnesoic acid O-methyltransferase*1
Insect Biochemistry and Molecular Biology, 2004 - Vitellogenesis in the red crabCharybdis feriatus: Hepatopancreas-specific expression and farnesoic acid stimulation of vitellogenin gene expression
Molecular Reproduction and Development, vol. 70, no. 3, pp. 288–300, 2004 - The distribution and effects of Dippu-allatostatin-like peptides in the blood-feeding bug, Rhodnius prolixus
Peptides, vol. 24, no. 10, pp. 1553–1562, 2003 - Comparative immunohistochemistry and cellular distribution of farnesoic acid O-methyltransferase in the shrimp and the crayfish
Peptides, vol. 24, no. 10, pp. 1591–1597, 2003 - Immunolocalization of allatostatin-like neuropeptides and their putative receptor in eyestalks of the tiger prawn, Penaeus monodon
Peptides, vol. 24, no. 10, pp. 1563–1570, 2003 - Localization and physiological effects of RFamides in the corpora allata of the cockroach Diploptera punctata in relation to allatostatins
Peptides, vol. 24, no. 10, pp. 1501–1510, 2003 - Crustacean neuropeptide genes of the CHH/MIH/GIH family: implications from molecular studies
General and Comparative Endocrinology, vol. 134, no. 3, pp. 214–219, 2003 - Quantification and visualization of Dippu-AST mRNA in the brain of adult Diploptera punctata: mated females vs. virgin females vs. males
Journal of Insect Physiology, vol. 49, no. 4, pp. 285–291, 2003 - Drosophila melanogaster flatline encodes a myotropin orthologue to Manduca sexta allatostatin
Peptides, vol. 23, no. 4, pp. 787–794, 2002 - Cardioacceleratory effects of Manduca sexta allatotropin in the true armyworm moth, Pseudaletia unipuncta
Peptides, vol. 23, no. 4, pp. 645–651, 2002 - Characterization and baculovirus-directed expression of a myosuppressin encoding cDNA from the true armyworm, Pseudaletia unipuncta
Peptides, vol. 23, no. 4, pp. 747–756, 2002 - Characterization of an additional molt inhibiting hormone-like neuropeptide from the shrimp Metapenaeus ensis
Peptides, vol. 23, no. 11, pp. 1875–1883, 2002 - Methyl farnesoate and juvenile hormone production in embryos of Diploptera punctata in relation to innervation of corpora allata and their sensitivity to allatostatin
Peptides, vol. 23, no. 11, pp. 1981–1990, 2002 - Expression of allatostatin in the oviducts of the cockroach Diploptera punctata
Insect Biochemistry and Molecular Biology, vol. 32, no. 9, pp. 1089–1099, 2002 - Function and cellular localization of farnesoic acid O-methyltransferase (FAMeT) in the shrimp, Metapenaeus ensis
European Journal of Biochemistry, vol. 269, no. 14, pp. 3587–3595, 2002 - Flights of fancy: possible roles of allatostatin and allatotropin in migration and reproductive success of Pseudaletia unipuncta?
Peptides, vol. 22, no. 2, pp. 271–277, 2001 - Biosynthetic Pathway of Insect Juvenile Hormone III in Cell Suspension Cultures of the Sedge Cyperus iria
PLANT PHYSIOLOGY, vol. 127, no. 2, pp. 584–593, 2001 - The radiochemical assay for juvenile hormone biosynthesis in insects: problems and solutions
Journal of Insect Physiology, vol. 47, no. 11, pp. 1227–1234, 2001 - Quantification of juvenile hormone III in the sedgeCyperus iria L.: comparison of HPLC and radioimmunoassay
Phytochemical Analysis, vol. 11, no. 1, pp. 21–28, 2000 - Partial Characterization of a Putative Allatostatin Receptor in the Midgut of the Cockroach Diploptera punctata
General and Comparative Endocrinology, vol. 119, no. 1, pp. 1–10, 2000 - Activity of insect juvenile hormone III: seed germination and seedling growth studies
Chemoecology, vol. 10, no. 2, pp. 89–97, 2000 - Cockroach diuretic hormones: Characterization of a calcitonin-like peptide in insects
Proceedings of the National Academy of Sciences, vol. 97, no. 12, pp. 6469–6474, 2000 - Molecular characterization of a cDNA from the true armyworm Pseudaletia unipuncta encoding Manduca sexta allatotropin peptide
Insect Biochemistry and Molecular Biology, vol. 30, no. 8-9, pp. 691–702, 2000 - Injection of Dip-allatostatin or Dip-allatostatin pseudopeptides into mated female Diploptera punctata inhibits endogenous rates of JH biosynthesis and basal oocyte growth
Insect Biochemistry and Molecular Biology, vol. 30, no. 8-9, pp. 703–710, 2000 - Terminal steps in JH biosynthesis in the honey bee (Apis mellifera L.): developmental changes in sensitivity to JH precursor and allatotropin
Insect Biochemistry and Molecular Biology, vol. 30, no. 8-9, pp. 729–737, 2000 - Biological activities of the allatostatin family of peptides in the cockroach, Diploptera punctata, and potential interactions with receptors
Journal of Insect Physiology, vol. 46, no. 3, pp. 231–242, 2000 - Developmental distribution of insect juvenile hormone III in the sedge, Cyperus iria L.
Phytochemistry, vol. 52, no. 7, pp. 1269–1274, 1999 - The molecular evolution of the allatostatin precursor in cockroaches
Peptides, vol. 20, no. 1, pp. 11–22, 1999 - Effects of an allatostatin and a myosuppressin on midgut carbohydrate enzyme activity in the cockroach Diploptera punctata
Peptides, vol. 20, no. 11, pp. 1285–1293, 1999 - The Regulation of Juvenile Hormone Production in Arthropods: Functional and Evolutionary Perspectives
Annals of the New York Academy of Sciences, vol. 897, no. 1 NEUROPEPTIDES, pp. 300–310, 1999 - Allatostatins: A Growing Family of Neuropeptides with Structural and Functional Diversity
Annals of the New York Academy of Sciences, vol. 897, no. 1 NEUROPEPTIDES, pp. 311–329, 1999 - Production of insect juvenile hormone III and its precursors in cell suspension cultures of the sedge, Cyperus iria L.
Plant Cell Reports, vol. 19, no. 1, pp. 20–25, 1999 - In situ hybridization analysis of leucomyosuppressin mRNA expression in the cockroach,Diploptera punctata
The Journal of Comparative Neurology, vol. 395, no. 3, pp. 328–341, 1998 - Ecdysiostatins and Allatostatins in Schistocerca gregaria
Annals of the New York Academy of Sciences, vol. 839, no. 1 TRENDS IN COM, pp. 301–305, 1998 - Synthesis, Biological Activity, and Conformational Studies of Insect Allatostatin Neuropeptide Analogues Incorporating Turn-Promoting Moieties
Bioorganic & Medicinal Chemistry, vol. 6, no. 8, pp. 1379–1388, 1998 - Partial characterization and isolation of earwig 'allatostatins': biological activities in earwigs and cockroaches
Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology, vol. 121, no. 4, pp. 395–403, 1998 - Molecular Characterization of the Inhibitory Myotropic Peptide Leucomyosuppressin
Peptides, vol. 18, no. 1, pp. 157–163, 1997 - Degradation of Dip-Allatostatins by Hemolymph From the Cockroach, Diploptera punctata
Peptides, vol. 18, no. 1, pp. 17–25, 1997 - Allatostatins: Diversity in Structure and Function of an Insect Neuropeptide Family
Annals of the New York Academy of Sciences, vol. 814, no. 1 Neuropeptides, pp. 53–66, 1997 - FMRFamide-related Peptides in Insects, with Emphasis on the Myosuppressins
Annals of the New York Academy of Sciences, vol. 814, no. 1 Neuropeptides, pp. 307–309, 1997 - Schistostatins
Annals of the New York Academy of Sciences, vol. 814, no. 1 Neuropeptides, pp. 327–330, 1997 - Molecular Characterization of the Manduca sexta-type of Allatostatin in the Migratory Moth Pseudaletia unipuncta
Annals of the New York Academy of Sciences, vol. 814, no. 1 Neuropeptides, pp. 346–349, 1997 - Inactivation of Dip-Allatostatin 5 by Membrane Preparations from the CockroachDiploptera punctata
General and Comparative Endocrinology, vol. 108, no. 2, pp. 258–270, 1997 - Role of second messengers in the regulation of juvenile hormone production in insects, with particular emphasis on calcium and phosphoinositide signaling
Archives of Insect Biochemistry and Physiology, vol. 33, no. 3-4, pp. 259–282, 1996 - Rate of isoleucine metabolism in lepidopteran corpora allata: Regulation of the proportion of juvenile hormone homologues released
Insect Biochemistry and Molecular Biology, vol. 26, no. 2, pp. 195–201, 1996 - Isolation and characterization of eight myoinhibiting peptides from the desert locust, Schistocerca gregaria: new members of the cockroach allatostatin family
Molecular and Cellular Endocrinology, vol. 122, no. 2, pp. 183–190, 1996 - Molecular cloning of the precursor cDNA for schistostatins, locust allatostatin-like peptides with myoinhibiting properties
Molecular and Cellular Endocrinology, vol. 122, no. 2, pp. 191–198, 1996 - Juvenile hormone esterase activity during the reproductive cycle of the ring-legged earwig1
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, vol. 114, no. 2, pp. 145–151, 1996 - Isolation and characterization of schistostatin-211–18 from the desert locust, Schistocerca gregaria: A truncated analog of schistostatin-2
Regulatory Peptides, vol. 67, no. 3, pp. 195–199, 1996 - Characterization of the gene for leucomyosuppressin and its expression in the brain of the cockroach Diploptera punctata
Insect Biochemistry and Molecular Biology, vol. 26, no. 6, pp. 627–637, 1996 - Molecular characterization of a cDNA from Pseudaletia unipuncta encoding the Manduca sexta allatostatin peptide (Mas-AST)
Insect Biochemistry and Molecular Biology, vol. 26, no. 8-9, pp. 767–773, 1996 - The characterization of a haemolymph methyl farnesoate binding protein and the assessment of methyl farnesoate metabolism by the haemolymph and other tissues from
Insect Biochemistry and Molecular Biology, vol. 25, no. 4, pp. 495–501, 1995 - Biosynthesis and release of juvenile hormone during the reproductive cycle of the ring-legged earwig
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology and Toxicology, vol. 110, no. 3, pp. 241–251, 1995 - Identification and partial characterization of receptors for allatostatins in brain and corpora allata of the cockroach using a binding assay and photoaffinity labeling
Regulatory Peptides, vol. 57, no. 3, pp. 347–358, 1995 - The effect of the thirteen Dip-allatostatins on myogenic and induced contractions of the cockroach (Diploptera punctata) hindgut
Journal of Insect Physiology, vol. 41, no. 7, pp. 581–588, 1995 - Immunochemical identification and expression of allatostatins in the gut of Diploptera punctata
Journal of Insect Physiology, vol. 41, no. 12, pp. 1035–1043, 1995 - Immunological evidence for an allatostatin-like neuropeptide in the central nervous system of Schistocerca gregaria , Locusta migratoria and Neobellieria bullata
Cell and Tissue Research, vol. 279, no. 3, pp. 601–611, 1995 - Cytosolic and Nuclear Juvenile Hormone-Binding Proteins from the Brain of Diploptera punctata
General and Comparative Endocrinology, vol. 94, no. 1, pp. 11–22, 1994 - Terminal stages in juvenile hormone biosynthesis in corpora allata of Diploptera punctata: Developmental changes in enzyme activity and regulation by allatostatins
Journal of Insect Physiology, vol. 40, no. 3, pp. 217–223, 1994 - Regulation of vitellogenin production in armyworm moths, Pseudaletia unipuncta
Journal of Insect Physiology, vol. 40, no. 2, pp. 129–136, 1994 - Factors affecting allatostatin release in a cockroach (Diploptera punctata): Nerve section, juvenile hormone analog and ovary
Journal of Insect Physiology, vol. 40, no. 5, pp. 365–372, 1994 - Structure-activity studies of allatostatin 4 on the inhibition of juvenile hormone biosynthesis by corpora allata: The importance of individual side chains and stereochemistry
Peptides, vol. 15, no. 7, pp. 1165–1171, 1994 - Two new allatostatins from the brains of Diploptera punctata
Insect Biochemistry and Molecular Biology, vol. 24, no. 3, pp. 257–263, 1994 - Signal transduction in the inhibition of juvenile hormone biosynthesis by allatostatins: roles of diacylglycerol and calcium
Molecular and Cellular Endocrinology, vol. 105, no. 1, pp. 89–96, 1994 - Molecular Cloning of the Gene for the Allatostatin Family of Neuropeptides from the Cockroach Diploptera punctata
Proceedings of the National Academy of Sciences, vol. 90, no. 19, pp. 8807–8811, 1993 - Callatostatins: Neuropeptides from the Blowfly Calliphora vomitoria with Sequence Homology to Cockroach Allatostatins
Proceedings of the National Academy of Sciences, vol. 90, no. 6, pp. 2456–2460, 1993 - Assessment of the role of cyclic nucleotides in allatostatin-induced inhibition of juvenile hormone biosynthesis in Diploptera punctata
Molecular and Cellular Endocrinology, vol. 89, no. 1-2, pp. 121–125, 1992 - Phosphoramidon enhances allatostatin-mediated inhibition of juvenile hormone biosynthesis in the corpora allta of the cockroach,Diploptera punctata
Experientia, vol. 48, no. 8, pp. 758–761, 1992 - Photoaffinity labeling of allatostatin receptor proteins in the corpora allata of the cockroach,
Biochemical and Biophysical Research Communications, vol. 181, no. 2, pp. 736–742, 1991 - Production and utilization of farnesoic acid in the juvenile hormone biosynthetic pathway by corpora allata of larval Diploptera punctata
General and Comparative Endocrinology, vol. 81, no. 2, pp. 284–294, 1991 - The effects of octopamine on juvenile hormone biosynthesis, electrophysiology, and cAMP content of the corpora allata of the cockroach Diploptera punctata
Journal of Comparative Physiology B, vol. 160, no. 3, pp. 241–249, 1990 - Production of methyl farnesoate by the mandibular organs of the mud crab, Scylla serrata: Validation of a radiochemical assay
General and Comparative Endocrinology, vol. 73, no. 3, pp. 342–353, 1989 - Primary Structure of Four Allatostatins: Neuropeptide Inhibitors of Juvenile Hormone Synthesis
Proceedings of the National Academy of Sciences, vol. 86, no. 15, pp. 5997–6001, 1989 - Differences in the stimulation by calcium ionophore of juvenile hormone III release from corpora allata of solitarious and gregariousLocusta migratoria
Experientia, vol. 44, no. 3, pp. 240–242, 1988 - Anatomy and electrophysiology of neurons terminating in the corpora allata of the cockroachDiploptera punctata
The Journal of Comparative Neurology, vol. 261, no. 1, pp. 120–129, 1987 - Evidence for an inhibitory role of cyclic AMP in the control of juvenile hormone biosynthesis by cockroach corpora allata
Molecular and Cellular Endocrinology, vol. 43, no. 2-3, pp. 155–163, 1985 - Control of corpus allatum activity inDiploptera punctata: roles of the pars intercerebralis and pars lateralis
Experientia, vol. 39, no. 12, pp. 1329–1334, 1983 - Ovarian stimulation of juvenile hormone biosynthesis in the viviparous cockroach,
General and Comparative Endocrinology, vol. 52, no. 3, pp. 341–349, 1983 - Nervous and humoral inhibition of C16 juvenile hormone synthesis in last instar females of the viviparous cockroach, Diploptera punctata
General and Comparative Endocrinology, vol. 49, no. 3, pp. 437–445, 1983 - Synthesis and degradation of C juvenile hormone (JH III) during the final two stadia of the cockroach,
General and Comparative Endocrinology, vol. 48, no. 1, pp. 25–32, 1982 - Intrinsic differences in juvenile hormone synthetic ability between corpora allata of males and females of the cockroach
General and Comparative Endocrinology, vol. 46, no. 4, pp. 533–540, 1982 - A rapid partition assay for routine analysis of juvenile hormone release by insect corpora allata
Analytical Biochemistry, vol. 111, no. 2, pp. 372–375, 1981 - Control of juvenile hormone biosynthesis during the reproductive cycle of a viviparous cockroach III. Effects of denervation and age on compensation with unilateral allatectomy and supernumerary corpora allata
General and Comparative Endocrinology, vol. 40, no. 1, pp. 89–98, 1980 - A secretion from neuroendocrine bag cells evokes egg release in vitro from ovotestis of Aplysia californica
General and Comparative Endocrinology, vol. 40, no. 2, pp. 241–244, 1980 - Modulation of juvenile hormone synthesis by an analogue in the cockroach
Nature, vol. 281, no. 5731, Article ID 281481a0, 1 pages, 1979 - Induction of vitellogenin and growth of implanted oocytes in male cockroaches
Nature, vol. 282, no. 5734, Article ID 282097a0, 1 pages, 1979 - Bag cell peptide acts directly on ovotestis of Aplysia californica: Basis for an in vitro bioassay
General and Comparative Endocrinology, vol. 36, no. 4, pp. 618–627, 1978 - Control of juvenile hormone biosynthesis during the reproductive cycle of a viviparous cockroach II. Effects of unilateral allatectomy, implantation of supernumerary corpora allata, and ovariectomy
General and Comparative Endocrinology, vol. 34, no. 3, pp. 276–286, 1978 - Control of juvenile hormone biosynthesis during the reproductive cycle of a viviparous cockroach I. Activation and inhibition of corpora allata
General and Comparative Endocrinology, vol. 33, no. 4, pp. 531–540, 1977 - Corpus allatum activity in vitro during the reproductive cycle of the viviparous cockroach, Diploptera punctata (eschscholtz)
General and Comparative Endocrinology, vol. 31, no. 1, pp. 138–147, 1977 - Inhibition of growth in developing oocytes of the desert locust
Experientia, vol. 33, no. 3, pp. 343–345, 1977 - Decay in juvenile hormone biosynthesis by insect corpus allatum after nerve transection
Nature, vol. 268, no. 5622, Article ID 268728a0, 2 pages, 1977 - Relative oxygenase activities in Juvenile hormone biosynthesis of corpora allata of an african locust (Schistocerca gregaria) and American cockroach (Periplaneta americana)
Experientia, vol. 31, no. 1, pp. 120–122, 1975 - Spontaneous synthesis and release of C16 juvenile hormone by isolated corpora allata of female locust Schistocerca gregaria and female cockroach Periplaneta americana
General and Comparative Endocrinology, vol. 26, no. 4, pp. 478–484, 1975 - The synthetic activity and glandular volume of the corpus allatum during ovarian maturation in the desert locust ?
Life Sciences, vol. 17, no. 3, pp. 417–422, 1975 - Structural and functional dynamics of oogenesis in : General features, previtellogenesis and nurse cells
Tissue and Cell, vol. 7, no. 2, pp. 297–317, 1975 - Structural and functional dynamics of oogenesis in : Vitellogenesis with special reference to the follicular epithelium
Tissue and Cell, vol. 7, no. 3, pp. 535–558, 1975 - Juvenile hormones radiobiosynthesised by corpora allata of adult female locusts ? ?
Life Sciences, vol. 14, no. 3, pp. 575–586, 1974 - Autoradiographic study of protein synthesis in abdominal tissues of
Tissue and Cell, vol. 6, no. 2, pp. 255–268, 1974 - Water movement during diuresis in the Tsetse fly (Glossina austeni)
Experientia, vol. 30, no. 5, pp. 517–518, 1974 - Dependence of juvenile hormone release from corpus allatum on intraglandular content
Nature, vol. 252, no. 5483, Article ID 252474a0, 2 pages, 1974 - Volume relationships during the larviposition cycle of Glossina austeni
Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 66, no. 2, p. 316, 1972