William S. Trimble
William S. Trimble obtained his Ph.D. degree in 1987 from the University of Toronto at the Laboratory of Dr. Nobumichi Hozumi, studying the mechanisms of cellular transformation by the RAS oncogene. He then did his postdoctoral work with Dr. Richard Scheller at Stanford University where he discovered the VAMP protein, the first member of the SNARE protein family that are responsible for membrane fusion. In 1990, Trimble rejoined the University of Toronto, and in 1995, he moved to the Hospital for Sick Children as a Senior Scientist. In 2006, he became the Head of the Cell Biology program at the Hospital for Sick Children. His current research has three main foci: membrane trafficking in the nervous system, the role of the septin family of GTPases in cytokinesis, and mechanisms controlling regulated membrane uptake in the innate immune system.
Biography Updated on 24 March 2009