Michael L. Bittner
Michael L. Bittner has done research on the
practical applications of biotechnology in
the fields of bioproduction of proteins, peptides,
and small molecules, and in development
of clinical diagnostics and therapeutics.
He has been a Researcher in both corporate
(Monsanto, Amoco) and research institute
(NIH, TGen) settings.
Biography Updated on 18 May 2006
Articles in Scholarly Journals [Incomplete List]
- A Robust Structural PGN Model for Control of Cell-Cycle Progression Stabilized by Negative Feedbacks
EURASIP Journal on Bioinformatics and Systems Biology, vol. 2007, Article ID 73109, 11 pages, 2007 - Validation of Computational Methods in Genomics
Current Genomics, vol. 8, no. 1, pp. 1–19, 2007 - Normalization Benefits Microarray-Based Classification
EURASIP Journal on Bioinformatics and Systems Biology, vol. 2006, Article ID 43056, 13 pages, 2006 - Generating Boolean networks with a prescribed attractor structure
Bioinformatics, vol. 21, no. 21, pp. 4021–4025, 2005 - Intervention in a family of Boolean networks
Bioinformatics, vol. 22, no. 2, pp. 226–232, 2005 - A window on the dynamics of biological switches
Nature Biotechnology, vol. 23, no. 2, Article ID nbt0205-183, 1 pages, 2005 - Stress-specific signatures: expression profiling of p53 wild-type and -null human cells
Oncogene, vol. 24, no. 28, Article ID 1208653, 7 pages, 2005 - Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome
Oncogene, vol. 23, no. 12, Article ID 1207337, 10 pages, 2004 - Functional genomics of UV radiation responses in human cells
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 549, no. 1-2, pp. 65–78, 2004 - External control in Markovian genetic regulatory networks: the imperfect information case
Bioinformatics, vol. 20, no. 6, pp. 924–930, 2004 - Growing genetic regulatory networks from seed genes
Bioinformatics, vol. 20, no. 8, pp. 1241–1247, 2004 - Which is better for cDNA-microarray-based classification: ratios or direct intensities
Bioinformatics, vol. 20, no. 16, pp. 2513–2520, 2004 - A Bayesian connectivity-based approach to constructing probabilistic gene regulatory networks
Bioinformatics, vol. 20, no. 17, pp. 2918–2927, 2004 - Intervention in context-sensitive probabilistic Boolean networks
Bioinformatics, vol. 21, no. 7, pp. 1211–1218, 2004 - Boolean relationships among genes responsive to ionizing radiation in the NCI 60 ACDS
Bioinformatics, vol. 21, no. 8, pp. 1542–1549, 2004 - Genomic Signal Processing: The Salient Issues
EURASIP Journal on Applied Signal Processing, vol. 2004, no. 1, pp. 146–153, 2004 - Noise factor analysis for cDNA microarrays
Journal of Biomedical Optics, vol. 9, no. 4, p. 663, 2004 - Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease
Human Molecular Genetics, vol. 12, no. 17, pp. 2191–2199, 2003 - Efficient selection of feature sets possessing high coefficients of determination based on incremental determinations
Signal Processing, vol. 83, no. 4, pp. 695–712, 2003 - Machine Learning, vol. 52, no. 1/2, pp. 169–191, 2003
- Gene-expression profiling in human cutaneous melanoma
Oncogene, vol. 22, no. 20, Article ID 1206448, 4 pages, 2003 - Functional genomics as a window on radiation stress signaling
Oncogene, vol. 22, no. 37, Article ID 1206681, 5 pages, 2003 - Mutation of melanosome protein RAB38 in chocolate mice
Proceedings of the National Academy of Sciences, vol. 99, no. 7, pp. 4471–4476, 2002 - Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma
Cancer Cell, vol. 1, no. 3, pp. 279–288, 2002 - Inference from Clustering with Application to Gene-Expression Microarrays
Journal of Computational Biology, vol. 9, no. 1, pp. 105–126, 2002 - Strong Feature Sets from Small Samples
Journal of Computational Biology, vol. 9, no. 1, pp. 127–146, 2002 - Assessing the significance of consistently mis-regulated genes in cancer associated gene expression matrices
Bioinformatics, vol. 18, no. 3, pp. 389–394, 2002 - Ratio statistics of gene expression levels and applications to microarray data analysis
Bioinformatics, vol. 18, no. 9, pp. 1207–1215, 2002 - Simulation of cDNA microarrays via a parameterized random signal model
Journal of Biomedical Optics, vol. 7, no. 3, p. 507, 2002 - Journal of Biological Systems, vol. 10, no. 4, p. 337, 2002
- Induction of Gene Expression as a Monitor of Exposure to Ionizing Radiation
Radiation Research, vol. 156, no. 5, p. 657, 2001 - Transcription Program of Human Herpesvirus 8 (Kaposi's Sarcoma-Associated Herpesvirus)
Journal of Virology, vol. 75, no. 10, pp. 4843–4853, 2001 - Biological indicators for the identification of ionizing radiation exposure in humans
Expert Review of Molecular Diagnostics, vol. 1, no. 2, pp. 211–219, 2001 - The Ca2+-binding Proteins S100A8 and S100A9 Are Encoded by Novel Injury-regulated Genes
Journal of Biological Chemistry, vol. 276, no. 38, pp. 35818–35825, 2001 - Physiological function as regulation of large transcriptional programs: the cellular response to genotoxic stress
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, vol. 129, no. 4, pp. 703–710, 2001 - Comprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancer
Proceedings of the National Academy of Sciences, vol. 98, no. 10, pp. 5711–5716, 2001 - Gene-Expression Profiles in Hereditary Breast Cancer
New England Journal of Medicine, vol. 344, no. 8, pp. 539–548, 2001 - Genome-wide expression changes induced by HTLV-1 Tax: evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-?B activation
Oncogene, vol. 20, no. 33, Article ID 1204513, 12 pages, 2001 - Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling
Oncogene, vol. 20, no. 46, Article ID 1204889, 5 pages, 2001 - Nature, vol. 406, no. 6795, pp. 536–540, 2000
- Chromosome arm-specific multicolor FISH
Genes, Chromosomes and Cancer, vol. 30, no. 1, pp. 105–109, 2000 - Identification of Tumor-Suppressor Genes Using Human Melanoma Cell Lines UACC903, UACC903(+6), and SRS3 by Comparison of Expression Profiles
Molecular Carcinogenesis, vol. 28, no. 2, pp. 119–127, 2000 - Multivariate Measurement of Gene Expression Relationships
Genomics, vol. 67, no. 2, pp. 201–209, 2000 - Positional Cloning Utilizing Genomic DNA Microarrays: The Niemann–Pick Type C Gene as a Model System
Molecular Genetics and Metabolism, vol. 70, no. 1, pp. 10–18, 2000 - General nonlinear framework for the analysis of gene interaction via multivariate expression arrays
Journal of Biomedical Optics, vol. 5, no. 4, p. 411, 2000 - Identification of Potential mRNA Biomarkers in Peripheral Blood Lymphocytes for Human Exposure to Ionizing Radiation
Radiation Research, vol. 154, no. 3, p. 342, 2000 - Detecting Activation of Ribosomal Protein S6 Kinase by Complementary DNA and Tissue Microarray Analysis
Journal of the National Cancer Institute, vol. 92, no. 15, pp. 1252–1259, 2000 - Differentially Painting Human Chromosome Arms with Combined Binary Ratio-labeling Fluorescence In Situ Hybridization
Genome Research, vol. 10, no. 6, pp. 861–865, 2000 - Microarrays and toxicology: The advent of toxicogenomics
Molecular Carcinogenesis, vol. 24, no. 3, pp. 153–159, 1999 - Expression profiling in cancer using cDNA microarrays
Electrophoresis, vol. 20, no. 2, pp. 223–229, 1999 - Nature Genetics, vol. 22, no. 3, pp. 213–215, 1999
- Expression profiling using cDNA microarrays
Nature Genetics, vol. 21, Article ID 4434, 4 pages, 1999 - Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses
Oncogene, vol. 18, no. 24, pp. 3666–3672, 1999 - Informatic selection of a neural crest-melanocyte cDNA set for microarray analysis
Proceedings of the National Academy of Sciences, vol. 96, no. 16, pp. 9277–9280, 1999 - cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene
Proceedings of the National Academy of Sciences, vol. 96, no. 23, pp. 13264–13269, 1999 - Nature Genetics, vol. 20, no. 1, pp. 19–23, 1998
- Chromosome Research, vol. 6, no. 1, pp. 25–33, 1998
- Comparative Genomic Hybridization: A Comparison with Molecular and Cytogenetic Analysis
Cancer Genetics and Cytogenetics, vol. 100, no. 2, pp. 93–105, 1998 - Restriction Mapping of Recombinant Cosmid Clones Using ? Terminase and Field Inversion Gel Electrophoresis
Analytical Biochemistry, vol. 245, no. 1, pp. 105–107, 1997 - A 2.8-Mb Clone Contig of the Multiple Endocrine Neoplasia Type 1 (MEN1) Region at 11q13
Genomics, vol. 42, no. 3, pp. 436–445, 1997 - Functional human CFTR produced by stable Chinese hamster ovary cell lines derived using yeast artificial chromosomes
Human Molecular Genetics, vol. 6, no. 1, pp. 59–68, 1997 - Molecular cytogenetic characterization and physical mapping of 12q13–15 amplification in human cancers
Genes, Chromosomes and Cancer, vol. 17, no. 4, pp. 205–214, 1996 - Chromosome arm painting probes
Nature Genetics, vol. 12, no. 1, Article ID ng0196-10, 1 pages, 1996 - Use of a cDNA microarray to analyse gene expression patterns in human cancer
Nature Genetics, vol. 14, no. 4, Article ID ng1296-457, 3 pages, 1996 - Identification by Representational Difference Analysis of a Homozygous Deletion in Pancreatic Carcinoma that Lies within the BRCA2 Region
Proceedings of the National Academy of Sciences, vol. 92, no. 13, pp. 5950–5954, 1995 - Expression, isolation and properties of Fur (ferric uptake regulation) protein ofEscherichia coli K 12
Biology of Metals, vol. 1, no. 1, pp. 62–68, 1988 - Expression of Bacterial Genes in Plant Cells
Proceedings of the National Academy of Sciences, vol. 80, no. 15, pp. 4803–4807, 1983