Bruno Meloni obtained his Science degree in 1985 and his Ph.D. degree in 1993. In 1996, Meloni joined the newly formed Stroke Research Group situated at the Australian Neuromuscular Research Institute (ANRI). Currently, he is the Head of Laboratory Research and has played a major role in overseeing its direction over the last 15 years. Meloni has been responsible for developing neuronal in vitro ischaemia (oxygen-glucose deprivation) and related injury models, establishing the recombinant adenovirus vector system, and overseeing the molecular and animal work being performed by the group. The work of the laboratory has focussed on molecular mechanisms of ischaemic neuronal degeneration and neuroprotection with the aim of developing potential treatments to minimize the brain damage following stroke and cerebral ischaemia. To this end, his research has been involved in i) identifying and characterizing potential neuroprotective proteins and peptides, ii) assessing the potential of the sodium calcium exchanger (NCX) membrane ion transporter to protect neurons from ischaemia, and iii) assessing the efficacy of mild hypothermia when used with magnesium and other putative neuroprotective agents/treatments.
Biography Updated on 24 March 2011