Marc Graille is a Biochemist with strong expertise in biochemistry, biophysics, crystallization, and X-ray protein crystallography. Graille received the Ph.D. degree in biochemistry and structural biology from Université Paris-Sud, France. During the Ph.D. at CEA Saclay, France, Graille studied the structural basis of the interactions between bacterial superantigens and B-cell receptors. During the postdoctoral period, Graille joined Pr Herman van Tilbeurgh's Group, University Paris-Sud, France, and was involved in the French structural genomics program centred on proteins from the yeast Saccharomyces cerevisiae. Graille is currently a CNRS Research Director at the Laboratory of Biochemistry (UMR7654/CNRS/Ecole Polytechnique, France). Graille is focusing on translation termination and its coupling to degradation of normal or aberrant mRNAs in eukaryotes, using structural and biochemical methods to unravel the mechanisms of these processes at the molecular level.
Biography Updated on 1 June 2012