Takashi Osumi

Articles in Scholarly Journals [Incomplete List]

  1. Metabolic pathway that produces essential fatty acids from polymethylene-interrupted polyunsaturated fatty acids in animal cells
    FEBS Journal, vol. 274, no. 11, pp. 2728–2737, 2007
  2. hDREF Regulates Cell Proliferation and Expression of Ribosomal Protein Genes
    Molecular and Cellular Biology, vol. 27, no. 6, pp. 2003–2013, 2007
  3. CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation
    The Journal of Lipid Research, vol. 48, no. 5, pp. 1078–1089, 2007
  4. Peroxisome Proliferator-Activated Receptor Subtypes Differentially Cooperate with Other Transcription Factors in Selective Transactivation of the Perilipin/PEX11  Gene Pair
    Journal of Biochemistry, vol. 139, no. 3, pp. 563–573, 2006
  5. Orphan Nuclear Receptor Nur77 Accelerates the Initial Phase of Adipocyte Differentiation in 3T3-L1 Cells by Promoting Mitotic Clonal Expansion
    Journal of Biochemistry, vol. 141, no. 2, pp. 181–192, 2006
  6. MLDP, a Novel PAT Family Protein Localized to Lipid Droplets and Enriched in the Heart, Is Regulated by Peroxisome Proliferator-activated Receptor  
    Journal of Biological Chemistry, vol. 281, no. 20, pp. 14232–14240, 2006
  7. Human DNA Replication-related Element Binding Factor (hDREF) Self-association via hATC Domain Is Necessary for Its Nuclear Accumulation and DNA Binding
    Journal of Biological Chemistry, vol. 282, no. 10, pp. 7563–7575, 2006
  8. Analysis of interaction partners for perilipin and ADRP on lipid droplets*
    Molecular and Cellular Biochemistry, vol. 284, no. 1-2, pp. 167–173, 2006
  9. Aspects of the regulatory mechanisms of PPAR functions: Analysis of a bidirectional response element and regulation by sumoylation
    Molecular and Cellular Biochemistry, vol. 286, no. 1-2, pp. 33–42, 2006
  10. Aberrant peroxisome morphology in peroxisomal beta-oxidation enzyme deficiencies
    Brain and Development, vol. 28, no. 5, pp. 287–292, 2006
  11. Identification of a Gene Sharing a Promoter and Peroxisome Proliferator-Response Elements With Acyl-CoA Oxidase Gene
    PPAR Research, vol. 2006, Article ID 71916, 10 pages, 2006
  12. Negative regulation of adipogenesis from human mesenchymal stem cells by Jun N-terminal kinase
    Biochemical and Biophysical Research Communications, vol. 326, no. 2, pp. 499–504, 2005
  13. Estrogen receptor-related receptor ? has an exceptionally broad specificity of DNA sequence recognition
    Gene, vol. 340, no. 2, pp. 275–282, 2004
  14. SKIP modifies gene expression by affecting both transcription and splicing
    Biochemical and Biophysical Research Communications, vol. 316, no. 2, pp. 512–517, 2004
  15. Identification of a new complementation group of the peroxisome biogenesis disorders andPEX14 as the mutated gene
    Human Mutation, vol. 23, no. 6, pp. 552–558, 2004
  16. CGI-58 Interacts with Perilipin and Is Localized to Lipid Droplets: POSSIBLE INVOLVEMENT OF CGI-58 MISLOCALIZATION IN CHANARIN-DORFMAN SYNDROME
    Journal of Biological Chemistry, vol. 279, no. 29, pp. 30490–30497, 2004
  17. The transactivating function of peroxisome proliferator-activated receptor gamma is negatively regulated by SUMO conjugation in the amino-terminal domain
    Genes to Cells, vol. 9, no. 11, pp. 1017–1029, 2004
  18. Tissue-Selective, Bidirectional Regulation of PEX11  and Perilipin Genes through a Common Peroxisome Proliferator Response Element
    Molecular and Cellular Biology, vol. 24, no. 3, pp. 1313–1323, 2004
  19. Functional characterization of a peroxisome proliferator response-element located in the intron 3 of rat peroxisomal thiolase B gene
    Biochemical and Biophysical Research Communications, vol. 311, no. 1, pp. 149–155, 2003
  20. Peroxisomes Are Formed from Complex Membrane Structures in PEX6-deficient CHO Cells upon Genetic Complementation
    Molecular Biology of the Cell, vol. 13, no. 2, pp. 711–722, 2002
  21. The Newly Identified Human Nuclear Protein NXP-2 Possesses Three Distinct Domains, the Nuclear Matrix-binding, RNA-binding, and Coiled-coil Domains
    Journal of Biological Chemistry, vol. 277, no. 23, pp. 20611–20617, 2002
  22. Carboxyl-terminal basic amino acids in the X domain are essential for the nuclear import of phospholipase C delta1
    Genes to Cells, vol. 7, no. 9, pp. 985–996, 2002
  23. Genetic and molecular bases of peroxisome biogenesis disorders
    Genetics in Medicine, vol. 3, no. 5, pp. 372–376, 2001
  24. Temperature sensitive acyl-CoA oxidase import in group A peroxisome biogenesis disorders
    Journal of Medical Genetics, vol. 38, no. 12, pp. 871–874, 2001
  25. Stabilization of Peroxisome Proliferator-Activated Receptor a by the Ligand
    Biochemical and Biophysical Research Communications, vol. 288, no. 1, pp. 106–110, 2001
  26. NXP-1, a Human Protein Related to Rad21/Scc1/Mcd1, Is a Component of the Nuclear Matrix
    Biochemical and Biophysical Research Communications, vol. 267, no. 1, pp. 418–422, 2000
  27. Molecular Mechanism of Detectable Catalase-Containing Particles, Peroxisomes, in Fibroblasts from a PEX2-Defective Patient
    Biochemical and Biophysical Research Communications, vol. 268, no. 1, pp. 31–35, 2000
  28. The Peroxisome Proliferator Response Element (PPRE) Present at Positions -681/-669 in the Rat Liver 3-Ketoacyl-CoA Thiolase B Gene Functionally Interacts Differently with PPARa and HNF-4
    Biochemical and Biophysical Research Communications, vol. 269, no. 2, pp. 347–351, 2000
  29. The 70-kDa Peroxisomal Membrane Protein (PMP70), an ATP-Binding Cassette Transporter
    Cell Biochemistry and Biophysics, vol. 32, no. 1-3, pp. 131–138, 2000
  30. Temperature Sensitivity in Peroxisome Assembly Processes Characterizes Milder Forms of Peroxisome Biogenesis Disorders
    Cell Biochemistry and Biophysics, vol. 32, no. 1-3, pp. 165–170, 2000
  31. Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors
    Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol. 1490, no. 1-2, pp. 189–197, 2000
  32. Restoration of biochemical function of the peroxisome in the temperature-sensitive mild forms of peroxisome biogenesis disorder in humans
    Brain and Development, vol. 22, no. 1, pp. 8–12, 2000
  33. Catalase-less Peroxisomes. IMPLICATION IN THE MILDER FORMS OF PEROXISOME BIOGENESIS DISORDER
    Journal of Biological Chemistry, vol. 275, no. 47, pp. 37271–37277, 2000
  34. Characterization of the 70-kDa Peroxisomal Membrane Protein, an ATP Binding Cassette Transporter
    Journal of Biological Chemistry, vol. 274, no. 17, pp. 11968–11976, 1999
  35. Characterization of the Amino-terminal Activation Domain of Peroxisome Proliferator-activated Receptor alpha . IMPORTANCE OF alpha -HELICAL STRUCTURE IN THE TRANSACTIVATING FUNCTION
    Journal of Biological Chemistry, vol. 274, no. 49, pp. 35152–35158, 1999
  36. Formation of Peroxisomes from Peroxisomal Ghosts in a Peroxisome-deficient Mammalian Cell Mutant upon Complementation by Protein Microinjection
    Journal of Biological Chemistry, vol. 274, no. 50, pp. 35293–35296, 1999
  37. Nonsense and temperature-sensitive mutations in PEX13 are the cause of complementation group H of peroxisome biogenesis disorders
    Human Molecular Genetics, vol. 8, no. 6, pp. 1077–1083, 1999
  38. Genomic structure and identification of 11 novel mutations of thePEX6 (peroxisome assembly factor-2) gene in patients with peroxisome biogenesis disorders
    Human Mutation, vol. 13, no. 6, pp. 487–496, 1999
  39. Functional Heterogeneity of C-Terminal Peroxisome Targeting Signal 1 in PEX5-Defective Patients
    Biochemical and Biophysical Research Communications, vol. 262, no. 2, pp. 504–508, 1999
  40. Peroxisome Biogenesis Disorders: Identification of a New Complementation Group Distinct from Peroxisome-Deficient CHO Mutants and Not Complemented by Human PEX 13
    Biochemical and Biophysical Research Communications, vol. 243, no. 2, pp. 368–371, 1998
  41. A Cytoplasmic AAA Family Peroxin, Pex1p, Interacts with Pex6p???
    Biochemical and Biophysical Research Communications, vol. 245, no. 3, pp. 883–886, 1998
  42. Genetic Basis of Peroxisome-Assembly Mutants of Humans, Chinese Hamster Ovary Cells, and Yeast: Identification of a New Complementation Group of Peroxisome-Biogenesis Disorders Apparently Lacking Peroxisomal-Membrane Ghosts
    The American Journal of Human Genetics, vol. 63, no. 6, pp. 1898–1903, 1998
  43. Nuclear receptor binding factor-1 (NRBF-1), a protein interacting with a wide spectrum of nuclear hormone receptors
    Gene, vol. 221, no. 2, pp. 225–233, 1998
  44. Human PEX1 cloned by functional complementation on a CHO cell mutant is responsible for peroxisome-deficient Zellweger syndrome of complementation group I
    Proceedings of the National Academy of Sciences, vol. 95, no. 8, pp. 4350–4355, 1998
  45. Isolation of a New Peroxisome-Deficient CHO Cell Mutant Defective in Peroxisome Targeting Signal-1 Receptor
    Biochemical and Biophysical Research Communications, vol. 230, no. 2, pp. 402–406, 1997
  46. Isolation and Characterization of Peroxisome-Deficient Chinese Hamster Ovary Cell Mutants Representing Human Complementation Group III
    Experimental Cell Research, vol. 233, no. 1, pp. 11–20, 1997
  47. An orphan nuclear receptor lacking a zinc-finger DNA-binding domain: interaction with several nuclear receptors
    Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol. 1350, no. 1, pp. 27–32, 1997
  48. Insertion of the 70-kDa Peroxisomal Membrane Protein into Peroxisomal Membranes in Vivo and in Vitro
    Journal of Biological Chemistry, vol. 271, no. 7, pp. 3706–3713, 1996
  49. A unified nomenclature for peroxisome biogenesis factors
    The Journal of Cell Biology, vol. 135, no. 1, pp. 1–3, 1996
  50. Analysis of Peroxisome Proliferator?responsive Enhancer of the Rat Acyl-CoA Oxidase Gene
    Annals of the New York Academy of Sciences, vol. 804, no. 1 Peroxisomes, pp. 202–213, 1996
  51. Cloning of Peroxisome Assembly Factor-2
    Annals of the New York Academy of Sciences, vol. 804, no. 1 Peroxisomes, pp. 656–657, 1996
  52. Sorting of the 70-kDa Peroxisomal Membrane Protein into Rat Liver Peroxisomes in Vitro
    Annals of the New York Academy of Sciences, vol. 804, no. 1 Peroxisomes, pp. 663–665, 1996
  53. Analysis of the Essential Sequence Elements in the Peroxisome Proliferator-Responsive Enhancer of Rat Acyl-CoA Oxidase Gene
    Annals of the New York Academy of Sciences, vol. 804, no. 1 Peroxisomes, pp. 706–708, 1996
  54. Cloning, Expression, and Characterization of cDNAs Encoding Arabidopsis thaliana Squalene Synthase
    Proceedings of the National Academy of Sciences, vol. 92, no. 6, pp. 2328–2332, 1995
  55. Peroxisome assembly factor–2, a putative ATPase cloned by functional complementation on a peroxisome–deficient mammalian cell mutant
    Nature Genetics, vol. 11, no. 4, Article ID ng1295-395, 6 pages, 1995
  56. Identification of two splice isoforms of mRNA for mouse hepatocyte nuclear factor 4 (HNF-4)
    Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol. 1260, no. 1, pp. 55–61, 1995
  57. Molecular cloning and functional expression of a cDNA for mouse squalene synthase
    Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol. 1260, no. 1, pp. 49–54, 1995
  58. Nucleotide sequence of a cDNA for mouse squalene epoxidase
    Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol. 1260, no. 3, pp. 345–348, 1995
  59. cDNA cloning of a putative G protein-coupled receptor from brain
    Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol. 1261, no. 1, pp. 121–125, 1995
  60. Assignment of the Human Peroxisome Assembly Factor-1 Gene (PXMP3) Responsible for Zellweger Syndrome to Chromosome 8q21.1 by Fluorescence in Situ Hybridization
    Genomics, vol. 20, no. 1, pp. 141–142, 1994
  61. Structure and expression of the genes encoding peroxisomal ß-oxidation enzymes
    Biochimie, vol. 75, no. 3-4, pp. 243–250, 1993
  62. Molecular basis of 3-ketothiolase deficiency: Detection of gene mutations and expression of mutant cDNAs of mitochondrial acetoacetyl-CoA thiolase
    Journal of Inherited Metabolic Disease, vol. 15, no. 5, pp. 815–820, 1992
  63. Amino-terminal presequence of the precursor of peroxisomal 3-ketoacyl-CoA thiolase is a cleavable signal peptide for peroxisomal targeting
    Biochemical and Biophysical Research Communications, vol. 181, no. 3, pp. 947–954, 1991
  64. Topogenesis of peroxisomal proteins
    BioEssays, vol. 12, no. 5, pp. 217–222, 1990
  65. Isolation and characterization of the rat catalase-encoding gene
    Gene, vol. 79, no. 2, pp. 279–288, 1989
  66. Molecular cloning and sequence analysis of the cDNA for rat mitochondrial enoyl-CoA hydratase. Structural and evolutionary relationships linked to the bifunctional enzyme of the peroxisomal beta-oxidation system
    European Journal of Biochemistry, vol. 185, no. 1, pp. 73–78, 1989
  67. Molecular cloning of cDNA for rat mitochondrial 3-oxoacyl-CoA thiolase
    European Journal of Biochemistry, vol. 154, no. 2, pp. 479–484, 1986
  68. The inducible fatty acid oxidation system in mammalian peroxisomes
    Trends in Biochemical Sciences, vol. 9, no. 7, pp. 317–319, 1984
  69. Molecular cloning of cDNA for rat liver catalase
    Biochemical and Biophysical Research Communications, vol. 122, no. 2, pp. 831–837, 1984
  70. Induction of peroxisomal ?-oxidation by the administration of acetylsalicylic acid*1
    Toxicology and Applied Pharmacology, vol. 59, no. 1, pp. 8–14, 1981
  71. Turnover of enzymes of peroxisomal ß-oxidation in rat liver
    Biochimica et Biophysica Acta (BBA) - General Subjects, vol. 630, no. 3, pp. 367–374, 1980
  72. Purification and properties of mitochondrial and peroxisomal 3-hydroxyacyl-CoA dehydrogenase from rat liver
    Archives of Biochemistry and Biophysics, vol. 203, no. 1, pp. 372–383, 1980
  73. The Presence of a New 3-Oxoacyl-CoA Thiolase in Rat Liver Peroxisomes
    European Journal of Biochemistry, vol. 103, no. 3, pp. 589–596, 1980
  74. Characterization of sterol-ester hydrolase in Saccharomyces cerevisiae
    Biochimica et Biophysica Acta (BBA) - Enzymology, vol. 525, no. 1, pp. 87–92, 1978
  75. Acyl-CoA oxidase of rat liver: A new enzyme for fatty acid oxidation
    Biochemical and Biophysical Research Communications, vol. 83, no. 2, pp. 479–485, 1978
  76. Effects of administration of di-(2-ethylhexyl)phthalate on rat liver mitochondria
    Biochemical Pharmacology, vol. 27, no. 23, pp. 2683–2688, 1978