Philippe Thullier received his M.D. degree in 1987 (Medical University in Lyon, Lyon, France) and his Ph.D. degree in 2001 (Doctoral School attached to the Museum of Natural History in Paris, France). Since 1987, he has been working for the health services of the French armed forces (Service de santé des armées), where he currently heads the “Biotechnology of Antibodies/Toxins” unit, part of IRBA (Institut de recherche biomédicale des armées, La Tronche, France). This unit is devoted to the use of antibodies to diagnose and treat conditions caused by bioweapons, particularly toxins. In particular, he has developed point-of-care tests based on antibodies for the diagnosis of intoxications caused by ricin and botulinum toxins. Utilizing an original approach (nonhuman primate antibodies, isolated using phage-displayed immune libraries and germline-humanized), he has isolated several therapeutic recombinant antibodies, including one neutralizing ricin and two neutralizing the anthrax lethal toxin. He presently coordinates the AntiBotABE European project aimed at isolating recombinant antibodies neutralizing botulinum toxins A, B, and E by this approach.
Biography Updated on 21 March 2011