Bernard Portha

Articles in Scholarly Journals [Incomplete List]

  1. Is Defective Pancreatic Beta-cell Mass Environmentally Programmed in Goto-Kakizaki Rat Model of Type 2 Diabetes?
    Pancreas, vol. 33, no. 4, pp. 412–417, 2006
  2. Islet Inflammation and Fibrosis in a Spontaneous Model of Type 2 Diabetes, the GK Rat
    Diabetes, vol. 55, no. 6, pp. 1625–1633, 2006
  3. Restitution of Defective Glucose-Stimulated Insulin Secretion in Diabetic GK Rat by Acetylcholine Uncovers Paradoxical Stimulatory Effect of  -Cell Muscarinic Receptor Activation on cAMP Production
    Diabetes, vol. 54, no. 11, pp. 3229–3237, 2005
  4. Programmed disorders of ß-cell development and function as one cause for type 2 diabetes? The GK rat paradigm
    Diabetes/Metabolism Research and Reviews, vol. 21, no. 6, pp. 495–504, 2005
  5. Protein-Caloric Food Restriction Affects Insulin-Like Growth Factor System in Fetal Wistar Rat
    Endocrinology, vol. 146, no. 3, pp. 1364–1371, 2004
  6. Keratinocyte growth factor and beta-cell differentiation in human fetal pancreatic endocrine precursor cells
    Diabetologia, vol. 46, no. 6, pp. 822–829, 2003
  7. Comparison between ?-[3-3H]- and ?-[5-3H]glucose and fructose utilization in pancreatic islets from control and hereditarily diabetic rats
    Archives of Biochemistry and Biophysics, vol. 408, no. 1, pp. 111–123, 2002
  8. Persistent Improvement of Type 2 Diabetes in the Goto-Kakizaki Rat Model by Expansion of the  -Cell Mass During the Prediabetic Period With Glucagon-Like Peptide-1 or Exendin-4
    Diabetes, vol. 51, no. 5, pp. 1443–1452, 2002
  9. Defective glucose-dependent cytosolic Ca2+ handling in islets of GK and nSTZ rat models of type 2 diabetes
    Journal of Endocrinology, vol. 169, no. 1, pp. 169–176, 2001
  10. Glucagon-Like Peptide-1 and Exendin-4 Stimulate  -Cell Neogenesis in Streptozotocin-Treated Newborn Rats Resulting in Persistently Improved Glucose Homeostasis at Adult Age
    Diabetes, vol. 50, no. 7, pp. 1562–1570, 2001
  11. Fetal Insulin-Like Growth Factor-2 Production Is Impaired in the GK Rat Model of Type 2 Diabetes
    Diabetes, vol. 51, no. 2, pp. 392–397, 2001
  12. The Histochemical Journal, vol. 33, no. 3, pp. 141–147, 2001
  13. Decreased pancreatic islet response to L-leucine in the spontaneously diabetic GK rat: enzymatic, metabolic and secretory data
    Diabetologia, vol. 42, no. 8, pp. 965–977, 1999
  14. Beta-cell growth in the neonatal Goto-Kakisaki rat and regeneration after treatment with streptozotocin at birth
    Diabetologia, vol. 42, no. 9, pp. 1098–1106, 1999
  15. Gaolf Identification by RT-PCR in Purified Normal Pancreatic B Cells and in Islets from Rat Models of Non-insulin-Dependent Diabetes
    Biochemical and Biophysical Research Communications, vol. 254, no. 1, pp. 269–272, 1999
  16. Metabolic and Secretory Response to ?-Fructose in Pancreatic Islets from Adult Rats Injected with Streptozotocin during the Neonatal Period
    Molecular Genetics and Metabolism, vol. 68, no. 1, pp. 86–90, 1999
  17. Metabolic and Secretory Interactions between D-Glucose and D-Fructose in Islets from GK Rats
    Endocrinology, vol. 140, no. 12, pp. 5556–5565, 1999
  18. Pancreatic beta-cell regeneration after 48-h glucose infusion in mildly diabetic rats is not correlated with functional improvement
    Diabetes, vol. 47, no. 7, pp. 1058–1065, 1998
  19. Altered Activity of the Autonomous Nervous System as a Determinant of the Impaired �-Cell Secretory Response after Protein-Energy Restriction in the Rat
    Endocrinology, vol. 139, no. 8, pp. 3382–3389, 1998
  20. Effect of gliclazide treatment on insulin secretion and ß-cell mass in non-insulin dependent diabetic Goto–Kakisaki rats
    European Journal of Pharmacology, vol. 361, no. 2-3, pp. 243–251, 1998
  21. Lack of deterioration of insulin action with aging in the GK rat: A contrasted adaptation as compared with nondiabetic rats
    Metabolism, vol. 46, no. 8, pp. 890–896, 1997
  22. Insulin secretion and glucose tolerance after islet transplantation in rats with noninsulin-dependent diabetes induced by neonatal streptozotocin
    Cell Transplantation, vol. 6, no. 1, pp. 23–32, 1997
  23. Contrasted Impact of Maternal Rat Food Restriction on the Fetal Endocrine Pancreas
    Endocrinology, vol. 138, no. 6, pp. 2267–2273, 1997
  24. Effects of Dehydroepiandrosterone in Rats Injected with Streptozotocin during the Neonatal Period
    Biochemical and Molecular Medicine, vol. 61, no. 1, pp. 72–81, 1997
  25. Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat
    Diabetologia, vol. 40, no. 8, pp. 916–925, 1997
  26. Alteration of the counterregulatory hormones in the conscious rat after protein-energy restriction
    Diabetologia, vol. 40, no. 9, pp. 1028–1034, 1997
  27. Glucagon-like peptide-1(7-36)-amide confers glucose sensitivity to previously glucose-incompetent beta-cells in diabetic rats: in vivo and in vitro studies
    Journal of Endocrinology, vol. 155, no. 2, pp. 369–376, 1997
  28. Decreased ATP-Induced Synthesis and Ca2+-Stimulated Degradation of Polyphosphoinositides in Pancreatic Islets from Neonatally Streptozotocin-Diabetic Rats
    Biochemical and Biophysical Research Communications, vol. 228, no. 2, pp. 573–578, 1996
  29. Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat
    Nature Genetics, vol. 12, no. 1, Article ID ng0196-38, 5 pages, 1996
  30. Mitochondrial deoxyribonucleic acid content is specifically decreased in adult, but not fetal, pancreatic islets of the Goto-Kakizaki rat, a genetic model of noninsulin-dependent diabetes
    Endocrinology, vol. 136, no. 12, pp. 5623–5631, 1995
  31. Changes in insulin action and insulin secretion in the rat after dietary restriction early in life: Influence of dood restriction versus low-protein food restriction*1
    Metabolism, vol. 44, no. 12, pp. 1519–1526, 1995
  32. Enzymatic and Secretory Activities in Pancreatic-Islets of Non-Insulin-Dependent Diabetic Rats after Short-Term Infusion of Succinic Acid Monomethyl Ester
    Biochemical Medicine and Metabolic Biology, vol. 53, no. 2, pp. 115–121, 1994
  33. Metabolic Response to Nonglucidic Nutrient Secretagogues and Enzymatic Activities in Pancreatic Islets of Adult Rats after Neonatal Streptozotocin Administration
    Biochemical Medicine and Metabolic Biology, vol. 49, no. 2, pp. 182–199, 1993
  34. Metabolic, Ionic, and Secretory Response to D-Glucose in Islets from Rats with Acquired or Inherited Non-Insulin-Dependent Diabetes
    Biochemical Medicine and Metabolic Biology, vol. 50, no. 3, pp. 301–321, 1993
  35. Preferential alteration of oxidative relative to total glycolysis in pancreatic islets of two rat models of inherited or acquired Type 2 (non-insulin-dependent) diabetes mellitus
    Diabetologia, vol. 36, no. 4, pp. 305–309, 1993
  36. In vivo and in vitro increased pancreatic beta-cell sensitivity to glucose in normal rats submitted to a 48-h hyperglycaemic period
    Diabetologia, vol. 36, no. 7, pp. 589–595, 1993
  37. Functional and metabolic perturbations in isolated pancreatic islets from the GK rat, a genetic model of noninsulin-dependent diabetes
    Endocrinology, vol. 132, no. 2, pp. 815–822, 1993
  38. Study of hexose transport, glycerol phosphate shuttle and Krebs cycle in islets of adult rats injected with streptozotocin during the neonatal period
    Molecular and Cellular Endocrinology, vol. 83, no. 2-3, pp. 95–104, 1992
  39. Increased insulin action in the rat after protein malnutrition early in life
    Diabetologia, vol. 34, no. 8, pp. 559–564, 1991
  40. Impairment of the mitochondrial oxidative response to D-glucose in pancreatic islets from adult rats injected with streptozotocin during the neonatal period
    Diabetologia, vol. 33, no. 11, pp. 654–660, 1990
  41. In vivo insulin resistance in streptozotocin-diabetic rats ? evidence for reversal following oral vanadate treatment
    Diabetologia, vol. 32, no. 3, pp. 185–190, 1989
  42. Insulin binding and insulin receptor tyrosine kinase activity are not altered in the liver of rats with non-insulin-dependent diabetes
    Biochemical and Biophysical Research Communications, vol. 152, no. 3, pp. 1015–1022, 1988
  43. Localization of Vasoactive Intestinal Peptide Binding Sites in Rat Pancreatic Islets by Computer-Assisted Analysis of Electron Microscopy Video-Autoradiographs
    Annals of the New York Academy of Sciences, vol. 527, no. 1 Vasoactive In, pp. 672–673, 1988
  44. A Computer-Assisted Analysis of Ultrastructural Autoradiographs Applied to the Localization of Vasoactive Intestinal Peptide Binding Sites in Pancreatic Acini
    Annals of the New York Academy of Sciences, vol. 527, no. 1 Vasoactive In, pp. 674–675, 1988
  45. Effect of high sucrose diet on insulin secretion and insulin action: a study in the normal rat
    Diabetologia, vol. 30, no. 4, pp. 252–258, 1987
  46. Structural requirements for gastric inhibitory polypeptide (GIP) receptor binding and stimulation of insulin release
    Peptides, vol. 7, pp. 75–78, 1986
  47. Decreased glucagon-stimulated cyclic AMP production by isolated liver cells of rats with type 2 diabetes
    Molecular and Cellular Endocrinology, vol. 32, no. 1, pp. 13–26, 1983
  48. Effect of diet on glucose tolerance and insulin response in chemically diabetic rats
    Metabolism, vol. 31, no. 12, pp. 1194–1199, 1982
  49. Chemical diabetes in the adult rat as the spontaneous evolution of neonatal diabetes
    Diabetologia, vol. 17, no. 6, pp. 371–377, 1979
  50. Postmaturity in the rat: Impairment of insulin, glucagon, and glycogen stores
    Diabetologia, vol. 12, no. 5, pp. 429–436, 1976