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David Brautigan
Articles in Scholarly Journals [Incomplete List]
Subunit composition and developmental regulation of hepatic protein phosphatase 2A (PP2A)
Archives of Biochemistry and Biophysics, vol. 461, no. 2, pp. 186–193, 2007
ATM regulates ionizing radiation-induced disruption of HDAC1:PP1:Rb complexes
Cellular Signalling, vol. 19, no. 3, pp. 504–510, 2007
Phosphorylation and Functions of Inhibitor-2 Family of Proteins
Biochemistry, vol. 46, no. 9, pp. 2380–2389, 2007
The Structure of Tap42/a4 Reveals a Tetratricopeptide Repeat-like Fold and Provides Insights into PP2A Regulation,
Biochemistry, vol. 46, no. 30, pp. 8807–8815, 2007
Association of the Tensin N-terminal Protein-tyrosine Phosphatase Domain with the Isoform of Protein Phosphatase-1 in Focal Adhesions
Journal of Biological Chemistry, vol. 282, no. 24, pp. 17806–17815, 2007
Cytokine Activation of p38 Mitogen-Activated Protein Kinase and Apoptosis Is Opposed by alpha-4 Targeting of Protein Phosphatase 2A for Site-Specific Dephosphorylation of MEK3
Molecular and Cellular Biology, vol. 27, no. 12, pp. 4217–4227, 2007
Ligand Binding to the Androgen Receptor Induces Conformational Changes That Regulate Phosphatase Interactions
Molecular and Cellular Biology, vol. 27, no. 9, pp. 3390–3404, 2007
Protein Phosphatase-1 Regulates Centrosome Splitting through Nek2
Cancer Research, vol. 67, no. 3, pp. 1082–1089, 2007
Expression of Ral GTPases, Their Effectors, and Activators in Human Bladder Cancer
Clinical Cancer Research, vol. 13, no. 13, pp. 3803–3813, 2007
Proper Chromatin Condensation and Maintenance of Histone H3 Phosphorylation During Mouse Oocyte Meiosis Requires Protein Phosphatase Activity
Biology of Reproduction, vol. 76, no. 4, pp. 628–638, 2006
Activation of glycogen synthase in myocardium induced by intermittent hypoxia is much lower in fasted than in fed rats
AJP: Endocrinology and Metabolism, vol. 292, no. 2, pp. E469–E475, 2006
The 4 Regulatory Subunit Exerts Opposing Allosteric Effects on Protein Phosphatases PP6 and PP2A
Journal of Biological Chemistry, vol. 281, no. 41, pp. 30503–30511, 2006
Protein Phosphatase 6 Subunit with Conserved Sit4-associated Protein Domain Targets I B
Journal of Biological Chemistry, vol. 281, no. 32, pp. 22624–22634, 2006
Protein Phosphatase 6 Down-regulates TAK1 Kinase Activation in the IL-1 Signaling Pathway
Journal of Biological Chemistry, vol. 281, no. 52, pp. 39891–39896, 2006
Peptide Microarray Analysis of Substrate Specificity of the Transmembrane Ser/Thr Kinase KPI-2 Reveals Reactivity with Cystic Fibrosis Transmembrane Conductance Regulator and Phosphorylase
Molecular & Cellular Proteomics, vol. 5, no. 11, pp. 2124–2130, 2006
Chromium and vanadate combination increases insulin-induced glucose uptake by 3T3-L1 adipocytes
Biochemical and Biophysical Research Communications, vol. 347, no. 3, pp. 769–773, 2006
Phosphorylation of the Pro-X-Thr-Pro site in phosphatase inhibitor-2 by cyclin-dependent protein kinase during M-phase of the cell cycle?
Cellular Signalling, vol. 18, no. 8, pp. 1318–1326, 2006
Systems analyses characterize integrated functions of biochemical networks
Trends in Biochemical Sciences, vol. 31, no. 5, pp. 284–291, 2006
Assembly of MYPT1 with protein phosphatase-1 in fibroblasts redirects localization and reorganizes the actin cytoskeleton
Cell Motility and the Cytoskeleton, vol. 62, no. 2, pp. 100–109, 2005
Biochemistry, vol. 44, no. 22, pp. 8167–8175, 2005
Biochemistry, vol. 44, no. 33, pp. 11067–11073, 2005
Biochemistry, vol. 44, no. 46, pp. 15422–15422, 2005
Simian Virus 40 Small t Antigen Mediates Conformation-Dependent Transfer of Protein Phosphatase 2A onto the Androgen Receptor
Molecular and Cellular Biology, vol. 25, no. 4, pp. 1298–1308, 2005
Journal of Translational Medicine, vol. 3, no. 1, p. 39, 2005
Migration and retraction of endothelial and epithelial cells require PHI-1, a specific protein-phosphatase-1 inhibitor protein
Journal of Cell Science, vol. 117, no. 24, pp. 5905–5912, 2004
Overlapping Binding Sites in Protein Phosphatase 2A for Association with Regulatory A and ?-4 (mTap42) Subunits
Journal of Biological Chemistry, vol. 279, no. 37, pp. 38912–38920, 2004
Phosphoprotein inhibitor CPI-17 specificity depends on allosteric regulation of protein phosphatase-1 by regulatory subunits
Proceedings of the National Academy of Sciences, vol. 101, no. 24, pp. 8888–8893, 2004
Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein
Proceedings of the National Academy of Sciences, vol. 101, no. 23, pp. 8625–8630, 2004
Juxtamembrane localization of the protein phosphatase-1 inhibitor protein PHI-1 in smooth muscle cells
Histochemistry and Cell Biology, vol. 121, no. 4, pp. 343–350, 2004
Phosphorylation-induced conformational change responsible for the function of a myosin phosphatase inhibitor, CPI-17
Science and Technology of Advanced Materials, vol. 5, no. 3, pp. 383–386, 2004
Phosphorylation of protein phosphatase type-1 inhibitory proteins by integrin-linked kinase and cyclic nucleotide-dependent protein kinases
Biochemical and Biophysical Research Communications, vol. 306, no. 2, pp. 382–387, 2003
Distinctive Solution Conformation of Phosphatase Inhibitor CPI-17 Substituted with Aspartate at the Phosphorylation-site Threonine Residue
Journal of Molecular Biology, vol. 326, no. 5, pp. 1539–1547, 2003
Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via Gi3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway
Biochemical Journal, vol. 374, no. 1, p. 145, 2003
Phosphorylation of Phosphatase Inhibitor-2 at Centrosomes during Mitosis
Journal of Biological Chemistry, vol. 278, no. 28, pp. 26015–26020, 2003
Phosphorylation of the Myosin-binding Subunit of Myosin Phosphatase by Raf-1 and Inhibition of Phosphatase Activity
Journal of Biological Chemistry, vol. 277, no. 4, pp. 3053–3059, 2002
ATM-dependent Dissociation of B55 Regulatory Subunit from Nuclear PP2A in Response to Ionizing Radiation
Journal of Biological Chemistry, vol. 277, no. 7, pp. 4839–4844, 2002
The Specificity of Extracellular Signal-regulated Kinase 2 Dephosphorylation by Protein Phosphatases
Journal of Biological Chemistry, vol. 277, no. 35, pp. 31818–31825, 2002
Neurabins Recruit Protein Phosphatase-1 and Inhibitor-2 to the Actin Cytoskeleton
Journal of Biological Chemistry, vol. 277, no. 48, pp. 46535–46543, 2002
Ionizing Radiation Activates Nuclear Protein Phosphatase-1 by ATM-dependent Dephosphorylation
Journal of Biological Chemistry, vol. 277, no. 44, pp. 41756–41761, 2002
Inhibitor-2 Regulates Protein Phosphatase-1 Complexed with NimA-related Kinase to Induce Centrosome Separation
Journal of Biological Chemistry, vol. 277, no. 46, pp. 44013–44020, 2002
A Novel Transmembrane Ser/Thr Kinase Complexes with Protein Phosphatase-1 and Inhibitor-2
Journal of Biological Chemistry, vol. 277, no. 51, pp. 49605–49612, 2002
Domains of type 1 protein phosphatase inhibitor-2 required for nuclear and cytoplasmic localization in response to cell-cell contact
Journal of Cell Science, vol. 115, no. 19, pp. 3739–3745, 2002
Targeting Protein Phosphatase 1 (PP1) to the Actin Cytoskeleton: the Neurabin I/PP1 Complex Regulates Cell Morphology
Molecular and Cellular Biology, vol. 22, no. 13, pp. 4690–4701, 2002
Phosphorylation of the myosin phosphatase inhibitors, CPI-17 and PHI-1, by integrin-linked kinase
Biochemical Journal, vol. 367, no. 2, p. 517, 2002
Cerebellar Long-Term Synaptic Depression Requires PKC-Mediated Activation of CPI-17, a Myosin/Moesin Phosphatase Inhibitor
Neuron, vol. 36, no. 6, pp. 1145–1158, 2002
Developmental expression of ?4 protein phosphatase regulatory subunit in tissues affected by Opitz syndrome
Developmental Dynamics, vol. 224, no. 4, pp. 461–464, 2002
Solution NMR structure of the myosin phosphatase inhibitor protein CPI-17 shows phosphorylation-induced conformational changes responsible for activation,
Journal of Molecular Biology, vol. 314, no. 4, pp. 839–849, 2001
Dual Ser and Thr phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by MYPT-associated kinase
FEBS Letters, vol. 493, no. 2-3, pp. 91–94, 2001
Histamine-induced Vasoconstriction Involves Phosphorylation of a Specific Inhibitor Protein for Myosin Phosphatase by Protein Kinase C alpha and delta Isoforms
Journal of Biological Chemistry, vol. 276, no. 31, pp. 29072–29078, 2001
Activation of Myosin Light Chain Phosphatase in Intact Arterial Smooth Muscle During Nitric Oxide-induced Relaxation
Journal of Biological Chemistry, vol. 276, no. 37, pp. 34681–34685, 2001
Phosphorylation and microtubule association of the Opitz syndrome protein mid-1 is regulated by protein phosphatase 2A via binding to the regulatory subunit alpha 4
Proceedings of the National Academy of Sciences, vol. 98, no. 12, pp. 6650–6655, 2001
Expression of CPI-17 and myosin phosphatase correlates with Ca2+ sensitivity of protein kinase C-induced contraction in rabbit smooth muscle
The Journal of Physiology, vol. 535, no. 2, pp. 553–564, 2001
Defining the Structural Determinants and a Potential Mechanism for Inhibition of Myosin Phosphatase by the Protein Kinase C-potentiated Inhibitor Protein of 17 kDa
Journal of Biological Chemistry, vol. 276, no. 43, pp. 39858–39863, 2001
Insulin-stimulated Phosphorylation of the Protein Phosphatase-1 Striated Muscle Glycogen-targeting Subunit and Activation of Glycogen Synthase
Journal of Biological Chemistry, vol. 275, no. 21, pp. 15940–15947, 2000
Agonists Trigger G Protein-mediated Activation of the CPI-17 Inhibitor Phosphoprotein of Myosin Light Chain Phosphatase to Enhance Vascular Smooth Muscle Contractility
Journal of Biological Chemistry, vol. 275, no. 14, pp. 9897–9900, 2000
Glycogen Synthase Association with the Striated Muscle Glycogen-targeting Subunit of Protein Phosphatase-1. SYNTHASE ACTIVATION INVOLVES SCAFFOLDING REGULATED BY beta -ADRENERGIC SIGNALING
Journal of Biological Chemistry, vol. 275, no. 34, pp. 26074–26081, 2000
Mutations of the serine phosphorylated in the protein phosphatase-1-binding motif in the skeletal muscle glycogen-targeting subunit
Biochemical Journal, vol. 346, no. 1, p. 77, 2000
Inhibition of myosin/moesin phosphatase by expression of the phosphoinhibitor protein CPI-17 alters microfilament organization and retards cell spreading
Cell Motility and the Cytoskeleton, vol. 46, no. 3, pp. 222–234, 2000
Protein Phosphatase 2A Suppresses MAP Kinase Signalling and Ectopic Protein Expression
Cellular Signalling, vol. 11, no. 8, pp. 575–580, 1999
Histone H1 Dephosphorylation Is Mediated through a Radiation-induced Signal Transduction Pathway Dependent on ATM
Journal of Biological Chemistry, vol. 274, no. 26, pp. 18715–18720, 1999
Biochemistry, vol. 38, no. 32, pp. 10371–10376, 1999
Biochemistry, vol. 38, no. 51, pp. 16952–16957, 1999
Protein Phosphatase 1 Is Targeted to Microtubules by the Microtubule-associated Protein Tau
Journal of Biological Chemistry, vol. 273, no. 34, pp. 21901–21908, 1998
A conserved domain for glycogen binding in protein phosphatase-1 targeting subunits
FEBS Letters, vol. 439, no. 1-2, pp. 185–191, 1998
Multisite Phosphorylation and the Nuclear Localization of Phosphatase Inhibitor 2-Green Fluorescent Protein Fusion Protein during S Phase of the Cell Growth Cycle
Journal of Biological Chemistry, vol. 272, no. 51, pp. 32308–32314, 1997
B cell receptor-associated protein alpha 4 displays rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A
Proceedings of the National Academy of Sciences, vol. 94, no. 20, pp. 10624–10629, 1997
Inactivation of Raf-1 by a Protein-tyrosine Phosphatase Stimulated by GTP and Reconstituted by G[IMAGE] Subunits
Journal of Biological Chemistry, vol. 271, no. 6, pp. 3119–3123, 1996
Biochemistry, vol. 35, no. 43, pp. 13858–13864, 1996
Tyrosine phosphorylation of phosphatase inhibitor 2
Journal of Cellular Biochemistry, vol. 57, no. 3, pp. 415–422, 1995
Flicking the switches: phosphorylation of serine/threonine protein phosphatases
Seminars in Cancer Biology, vol. 6, no. 4, pp. 211–217, 1995
Concurrent Purification of Type-1 and Type-2A Protein Phosphatase Catalytic Subunits
Protein Expression and Purification, vol. 5, no. 3, pp. 211–217, 1994
Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A
Nature, vol. 369, no. 6477, Article ID 369230a0, 2 pages, 1994
Serine phosphorylation of protein tyrosine phosphatase (PTP1B) in HeLa cells in response to analogues of cAMP or diacylglycerol plus okadaic acid
Molecular and Cellular Biochemistry, vol. 127-128, no. 1, pp. 121–129, 1993
Great expectations: protein tyrosine phosphatases in cell regulation
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol. 1114, no. 1, pp. 63–77, 1992
Protein phosphatases modulate the apparent agonist affinity of the light-regulated ion channel in retinal rods
Neuron, vol. 9, no. 4, pp. 739–748, 1992
Raf-1 activates MAP kinase-kinase
Nature, vol. 358, no. 6385, Article ID 358417a0, 4 pages, 1992
Cytoskeletal Integrity in Interphase Cells Requires Protein Phosphatase Activity
Proceedings of the National Academy of Sciences, vol. 89, no. 22, pp. 11093–11097, 1992
Protein phosphatase type 1 in mammalian cell mitosis: chromosomal localization and involvement in mitotic exit
The Journal of Cell Biology, vol. 116, no. 6, pp. 1421–1430, 1992
Activation of Membrane Protein-Tyrosine Phosphatase Involving cAMP- and Ca2+/Phospholipid-Dependent Protein Kinases
Proceedings of the National Academy of Sciences, vol. 88, no. 15, pp. 6696–6700, 1991
Interleukio 2 stimulates serine phosphorylation of CD45 in CTLL-2.4 cells
European Journal of Immunology, vol. 21, no. 4, pp. 913–919, 1991
Modulation of type-1 protein phosphatase by synthetic peptides corresponding to the carboxyl terminus
FEBS Letters, vol. 285, no. 1, pp. 6–10, 1991
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A
Cell, vol. 60, no. 1, pp. 167–176, 1990
Protein phosphatase type-1, not type-2A, modulates actin microfilament integrity and myosin light chain phosphorylation in living nonmuscle cells
The Journal of Cell Biology, vol. 111, no. 1, pp. 103–112, 1990
Involvement of protein phosphatases 1 and 2A in the control of M phase- promoting factor activity in starfish
The Journal of Cell Biology, vol. 109, no. 6, pp. 3347–3354, 1989
Protein phosphatase type 1 catalytic subunit forms nondissociable dimers*1
Archives of Biochemistry and Biophysics, vol. 275, no. 1, pp. 44–52, 1989
Calyculin A and okadaic acid: Inhibitors of protein phosphatase activity
Biochemical and Biophysical Research Communications, vol. 159, no. 3, pp. 871–877, 1989
Molecular defects in ion channel regulation in cystic fibrosis predicted from analysis of protein phosphorylation/dephosphorylation
International Journal of Biochemistry, vol. 20, no. 8, pp. 745–752, 1988
Proposal for a pathway to mediate the metabolic effects of insulin
International Journal of Biochemistry, vol. 20, no. 4, pp. 349–356, 1988
Human Liver Phosphatase 2A: cDNA and Amino Acid Sequence of Two Catalytic Subunit Isotypes
Proceedings of the National Academy of Sciences, vol. 85, no. 12, pp. 4252–4256, 1988
Metal chelate affinity chromatography of Zn2+-inhibited protein Tyr(P) phosphatases
Journal of Biochemical and Biophysical Methods, vol. 14, no. 5, pp. 273–278, 1987
Latent forms of type-1 protein phosphatase in rabbit skeletal muscle
Biochemical and Biophysical Research Communications, vol. 148, no. 3, pp. 1174–1181, 1987
Molecular basis for substrate specificity of protein kinases and phosphatases
International Journal of Biochemistry, vol. 18, no. 6, pp. 497–504, 1986
Phosphorylation of chloroform soluble compounds in plasma membranes of human epidermoid carcinoma A431 cells
Lipids, vol. 20, no. 7, pp. 492–495, 1985
Biochemistry, vol. 22, no. 14, pp. 3393–3399, 1983
Biochemistry, vol. 21, no. 9, pp. 1977–1982, 1982
Dephosphorylation of skeletal muscle phosphorylase, glycogen synthase, and phosphorylase kinase ?-subunit by a Mn-activated protein phosphatase
Archives of Biochemistry and Biophysics, vol. 219, no. 1, pp. 228–235, 1982
Biochemistry, vol. 21, no. 22, pp. 5577–5584, 1982
Tyrosylprotein Kinase and Phosphatase Activities in Membrane Vesicles from Normal and Rous Sarcoma Virus-Transformed Rat Cells
Proceedings of the National Academy of Sciences, vol. 78, no. 11, pp. 6689–6693, 1981
Insulin and Glucose 6-Phosphate Stimulation of Ca2+ Uptake by Skinned Muscle Fibers
Proceedings of the National Academy of Sciences, vol. 77, no. 2, pp. 936–939, 1980
Mapping of Anion Binding Sites on Cytochrome c by Differential Chemical Modification of Lysine Residues
Proceedings of the National Academy of Sciences, vol. 77, no. 8, pp. 4439–4443, 1980
Biochemistry, vol. 19, no. 25, pp. 5787–5794, 1980
Biochemistry, vol. 17, no. 11, pp. 2246–2249, 1978
Preparation of cytochrome from
Analytical Biochemistry, vol. 72, no. 1-2, pp. 255–260, 1976