Carlos Blanco held the position of an Engineer in biochemistry at INSA, Lyon, France, in 1980. He obtained his Ph.D. degree in biochemistry from INSA, Lyon, France in 1982 and completed his Thesis in microbiology at INSA, Lyon, France in 1985. As for his academic positions, he was an Assistant Lecturer in microbiology at the INSA, Lyon, France, from 1980 to 1985, a Researcher at the French National Institute of Health (INSERM), Paris, France, from 1985 to 1989, and a Professor of Microbiology, University of Rennes, Rennes, France from 1989 to 2012. His area of expertise includes microbial physiology (e.g., characterization of metabolic pathways for polysaccharide and oil metabolism), bacterial genetics (e.g., characterization of phages and plasmids in bacteria and genome sequence and annotation), stress (e.g., osmotic, nutritional, and oxidative stress), and regulation of gene expression (e.g., characterization of effectors involved in transcriptional and translational regulation). His recent research activity is about hyperosmotic stress results in the loss of turgor pressure. The first response of cells deals with turgor recovery by accumulation of compatible solutes by neosynthesis (trehalose, glutamate, and glucosylglycerol) or by active uptake from the medium (glycine betaine and ectoine). Compatible solutes also exert a beneficial effect on metabolism and are important for the resistance to other stresses. Adaptation to oxidative stress results mainly in the synthesis of enzymes involved in detoxification (peroxidases and superoxide dismutases) and repair of macromolecules. His work deals with the characterization of enzymatic actors of osmotic and oxidative stress defense and the transcriptional regulation of their synthesis.
Biography Updated on 30 January 2013