Christopher Jolly

Christopher Jolly received his B.S. and Ph.D degrees in nutrition from Texas A&M University. His graduate work on the impact of n-3 fatty acids on lymphocyte signaling led to two national research awards (1995, 1996) given by the American Society of Nutrition. Dr. Jolly then completed two postdoctors, one for two years in lipid biochemistry and biophysics at Texas A&M University and the second for three years in nutrition, immunology, and aging in rodents at The University of Texas Health Science Center at San Antonio. Dr. Jolly was an Assistant Professor at The University of Texas at Austin from 2000 to 2006. In 2004, he won the prestigious BioServ Award from the American Society for Nutrition given for meritorious research in nutrition using experimental animal models. Dr. Jolly’s research examines the impact of aging on lipid metabolism and signaling in T-lymphocytes. The lab currently utilizes mouse knockout models in phospholipid metabolism and intracellular lipid signaling to elucidate mechanism(s) of aged T-lymphocyte dysfunction. Dr. Jolly is currently an Associate Professor with tenure at The University of Texas at Austin, where he is an Associate Chair of the Department of Human Ecology and Member of the Executive Committee for the Barshop Institute for Longevity and Aging Studies in San Antonio, TX.

Biography Updated on 17 May 2007

Articles in Scholarly Journals [Incomplete List]

  1. Is dietary restriction beneficial for human health, such as for immune function?
    Current Opinion in Lipidology, vol. 18, no. 1, p. 53???57, 2007
  2. Phosphorylation regulates mitochondrial glycerol-3-phosphate-1 acyltransferase activity in T-lymphocytes
    Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol. 1761, no. 1, pp. 129–139, 2006
  3. Dietary nâ??3 polyunsaturated fatty acids increase T-lymphocyte phospholipid mass and acyl-CoA binding protein expression
    Lipids, vol. 40, no. 1, pp. 81–87, 2005
  4. Aging reduces glycerol-3-phosphate acyltransferase activity in activated rat splenic T-lymphocytes
    Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol. 1687, no. 1-3, pp. 164–172, 2005
  5. CD28 activation does not down-regulate Cbl-b expression in aged rat T-lymphocytes
    Mechanisms of Ageing and Development, vol. 125, no. 9, pp. 595–602, 2004
  6. Aging and acyl-CoA binding protein alter mitochondrial glycerol-3-phosphate acyltransferase activity
    Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol. 1631, no. 1, pp. 12–16, 2003
  7. Albumin stimulates lysophosphatidic acid acyltransferase activity in T-lymphocyte membranes
    Lipids, vol. 37, no. 5, pp. 475–480, 2002
  8. Maintenance of NF-?B Activation in T-Lymphocytes and a Naive T-Cell Population in Autoimmune-Prone (NZB/NZW)F1 Mice by Feeding a Food-Restricted Diet Enriched with n-3 Fatty Acids
    Cellular Immunology, vol. 213, no. 2, pp. 122–133, 2001
  9. Reduced food consumption increases water intake and modulates renal Aquaporin-1 and-2 expression in autoimmune prone mice
    Life Sciences, vol. 66, no. 16, pp. 1471–1479, 2000
  10. Journal of Clinical Immunology, vol. 20, no. 5, pp. 354–361, 2000
  11. Molecular and Cellular Biochemistry, vol. 205, no. 1/2, pp. 83–90, 2000
  12. Microsomal fatty acyl-CoA transacylation and hydrolysis: fatty acyl-CoA species dependent modulation by liver fatty acyl-CoA binding proteins
    Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol. 1483, no. 1, pp. 185–197, 2000
  13. Dietary N-3 Fatty Acids and Calorie Restriction in Autoimmune Disease: Influence in Different Immune Compartments
    Current Organic Chemistry, vol. 4, no. 11, pp. 1091–1109, 2000
  14. Journal of Clinical Immunology, vol. 19, no. 3, pp. 172–178, 1999
  15. The effects of dietary lipids on gene expression and apoptosis
    Proceedings of the Nutrition Society, vol. 57, no. 4, pp. 543–550, 1998
  16. Effect of dietary n-3 fatty acids on interleukin-2 and interleukin-2 receptor a expression in activated murine lymphocytes
    Prostaglandins, Leukotrienes and Essential Fatty Acids, vol. 58, no. 4, pp. 289–293, 1998
  17. Structure and Function of Normal and Transformed Murine Acyl-CoA Binding Proteins
    Archives of Biochemistry and Biophysics, vol. 350, no. 2, pp. 201–213, 1998
  18. Differential influence of rat liver fatty acid binding protein isoforms on phospholipid fatty acid composition: phosphatidic acid biosynthesis and phospholipid fatty acid remodeling
    Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol. 1390, no. 3, pp. 258–268, 1998
  19. Fatty acid binding protein isoforms: structure and function
    Chemistry and Physics of Lipids, vol. 92, no. 1, pp. 1–25, 1998
  20. Fatty Acid Binding Protein: Stimulation of Microsomal Phosphatidic Acid Formation,
    Archives of Biochemistry and Biophysics, vol. 341, no. 1, pp. 112–121, 1997
  21. Biochemistry, vol. 36, no. 7, pp. 1719–1729, 1997
  22. Alteration of glycerolipid and sphingolipid-derived second messenger kinetics in ras transformed 3T3 cells
    Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol. 1299, no. 1, pp. 146–154, 1996
  23. Diacylglycerol and ceramide kinetics in primary cultures of activated T-lymphocytes
    Immunology Letters, vol. 49, no. 1-2, pp. 43–48, 1996
  24. Dietary fat and fiber differentially alter intracellular second messengers during tumor devolopment in rat colon
    Carcinogenesis, vol. 17, no. 6, pp. 1227–1233, 1996