Dezheng Zhao received a Ph.D. degree in biochemistry from Boston University School of Medicine in 2000. Zhao's thesis was to study the signaling mechanism of proinflammatory lipoprotein, very low density lipoprotein (VLDL), in regulating aortic smooth muscle function. Zhao also studied the mechanism by which angiogenic and proinflammatory mediator vascular endothelial growth factor (VEGF) in regulating pathological angiogenesis. Zhao was promoted to Instructor in medicine in 2002 and Assistant Professor of medicine in 2007, respectively, at Beth Israel Deaconess Medical Center Harvard Medical School. Zhao's research interest and expertise is on the pathophysiology and molecular regulation of intestinal inflammation with focus on two major aspects. The first is on the role and proinflammatory signaling mechanism of gastrointestinal neuropeptides ghrelin, neurotensin, and neuromedin U in inflammatory bowel diseases (IBD). The second is on how angiogenesis participated in the regulation of intestinal inflammation, particularly on VEGF and its downstream transcription factor Nur77 family of orphan nuclear receptors in pathological angiogenesis and intestinal inflammation.
Biography Updated on 2 May 2011