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Articles in Scholarly Journals [Incomplete List]

1. 1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, ßarrestin and RACK1
   Cellular Signalling, vol. 19, no. 12, pp. 2612–2624, 2007
2. Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of ß-arrestin using spot-immobilized peptide arrays
   Biochemical Journal, vol. 404, no. 1, p. 71, 2007
3. Dynamic regulation, desensitization and crosstalk in discrete sub-cellular microdomains during Beta2-adrenoceptor and prostanoid receptor cAMP signalling
   Journal of Biological Chemistry, 2007
4. p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway
   The Journal of Cell Biology, vol. 177, no. 6, pp. 1119–1132, 2007
5. PDE4B5, a Novel, Super-Short, Brain-Specific cAMP Phosphodiesterase-4 Variant Whose Isoform-Specifying N-Terminal Region Is Identical to That of cAMP Phosphodiesterase-4D6 (PDE4D6)
   Journal of Pharmacology and Experimental Therapeutics, vol. 322, no. 2, pp. 600–609, 2007
6. Chemoresistant KM12C Colon Cancer Cells Are Addicted to Low Cyclic AMP Levels in a Phosphodiesterase 4-Regulated Compartment via Effects on Phosphoinositide 3-Kinase
   Cancer Research, vol. 67, no. 11, pp. 5248–5257, 2007
7. cAMP-Specific Phosphodiesterase-4 Enzymes in the Cardiovascular System: A Molecular Toolbox for Generating Compartmentalized cAMP Signaling
   Circulation Research, vol. 100, no. 7, pp. 950–966, 2007
8. Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D Is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
   Journal of the American Society of Nephrology, vol. 18, no. 1, pp. 199–212, 2007
9. Receptor dependent cellular uptake of synthetic low density lipoprotein by mammalian cells in serum-free tissue culture
   Journal of Pharmacy and Pharmacology, vol. 58, no. 10, pp. 1337–1342, 2006
10. PGE1 stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases
    The Journal of Cell Biology, vol. 175, no. 3, pp. 441–451, 2006
11. Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293ß2 cells and cardiac myocytes
    Biochemical Journal, vol. 394, no. 2, p. 427, 2006
12. Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, ß-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5
    Biochemical Journal, vol. 398, no. 1, p. 23, 2006
13. Phosphodiesterase-4 gates the ability of protein kinase A to phosphorylate G-protein receptor kinase-2 and influence its translocation
    Biochemical Society Transactions, vol. 34, no. 4, p. 474, 2006
14. cAMP phosphodiesterase-4A1 (PDE4A1) has provided the paradigm for the intracellular targeting of phosphodiesterases, a process that underpins compartmentalized cAMP signalling
    Biochemical Society Transactions, vol. 34, no. 4, p. 504, 2006
15. Spatial organisation of AKAP18 and PDE4 isoforms in renal collecting duct principal cells
    European Journal of Cell Biology, vol. 85, no. 7, pp. 673–678, 2006
16. Reduced PDE4 expression and activity contributes to enhanced catecholamine-induced cAMP accumulation in adipocytes from FOXC2 transgenic mice
    FEBS Letters, vol. 580, no. 17, pp. 4126–4130, 2006
17. Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract
    FEBS Letters, vol. 579, no. 15, pp. 3264–3270, 2005
18. Arrestin times for compartmentalised cAMP signalling and phosphodiesterase-4 enzymes
    Current Opinion in Cell Biology, vol. 17, no. 2, pp. 129–134, 2005
19. Compartmentalized cAMP signalling regulates vasopressin-mediated water reabsorption by controlling aquaporin-2
    Biochemical Society Transactions, vol. 33, no. 6, p. 1316, 2005
20. ß-Arrestin-recruited phosphodiesterase-4 desensitizes the AKAP79/PKA-mediated switching of ß2-adrenoceptor signalling to activation of ERK
    Biochemical Society Transactions, vol. 33, no. 6, p. 1333, 2005
21. RNA Silencing Identifies PDE4D5 as the Functionally Relevant cAMP Phosphodiesterase Interacting with  Arrestin to Control the Protein Kinase A/AKAP79-mediated Switching of the  2-Adrenergic Receptor to Activation of ERK in HEK293B2 Cells
    Journal of Biological Chemistry, vol. 280, no. 39, pp. 33178–33189, 2005
22. DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signaling
    Science, vol. 310, no. 5751, pp. 1187–1191, 2005
23. Differential expression of PDE4 cAMP phosphodiesterase isoforms in inflammatory cells of smokers with COPD, smokers without COPD, and nonsmokers
    AJP: Lung Cellular and Molecular Physiology, vol. 287, no. 2, pp. L332–L343, 2004
24. Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte-macrophage differentiation of human U937 cells
    British Journal of Pharmacology, vol. 142, no. 2, Article ID 0705770, 12 pages, 2004
25. Expression, intracellular distribution and basis for lack of catalytic activity of the PDE4A7 isoform encoded by the human PDE4A cAMP-specific phosphodiesterase gene
    Biochemical Journal, vol. 380, no. 2, p. 371, 2004
26. Molecular cloning and subcellular distribution of the novel PDE4B4 cAMP-specific phosphodiesterase isoform
    Biochemical Journal, vol. 370, no. 2, p. 429, 2003
27. beta -Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta -adrenoceptor switching from Gs to Gi
    Proceedings of the National Academy of Sciences, vol. 100, no. 3, pp. 940–945, 2003
28. Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process
    Cellular Signalling, vol. 15, no. 10, pp. 955–971, 2003
29. Attenuation of the Activity of the cAMP-specific Phosphodiesterase PDE4A5 by Interaction with the Immunophilin XAP2
    Journal of Biological Chemistry, vol. 278, no. 35, pp. 33351–33363, 2003
30. The Unique Amino-terminal Region of the PDE4D5 cAMP Phosphodiesterase Isoform Confers Preferential Interaction with  -Arrestins
    Journal of Biological Chemistry, vol. 278, no. 49, pp. 49230–49238, 2003
31. TAPAS-1, a Novel Microdomain within the Unique N-terminal Region of the PDE4A1 cAMP-specific Phosphodiesterase That Allows Rapid, Ca2+-triggered Membrane Association with Selectivity for Interaction with Phosphatidic Acid
    Journal of Biological Chemistry, vol. 277, no. 31, pp. 28298–28309, 2002
32. Targeting of Cyclic AMP Degradation to beta 2-Adrenergic Receptors by beta -Arrestins
    Science, vol. 298, no. 5594, pp. 834–836, 2002
33. Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)
    British Journal of Pharmacology, vol. 136, no. 3, Article ID 0704743, 12 pages, 2002
34. Physicochemical properties of microemulsion analogues of low density lipoprotein containing amphiphatic apoprotein B receptor sequences
    International Journal of Pharmaceutics, vol. 228, no. 1-2, pp. 109–117, 2001
35. Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases
    British Journal of Pharmacology, vol. 131, no. 4, Article ID 0703636, 8 pages, 2000
36. ERK2 Mitogen-activated Protein Kinase Binding, Phosphorylation, and Regulation of the PDE4D cAMP-specific Phosphodiesterases. THE INVOLVEMENT OF COOH-TERMINAL DOCKING SITES AND NH2-TERMINAL UCR REGIONS
    Journal of Biological Chemistry, vol. 275, no. 22, pp. 16609–16617, 2000
37. Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents
    Journal of Antimicrobial Chemotherapy, vol. 46, no. 3, pp. 397–403, 2000
38. The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579
    The EMBO Journal, vol. 18, no. 4, Article ID 7591524, 10 pages, 1999
39. Increased cytochrome P-450 activity in Aspergillus fumigatus after xenobiotic exposure
    Medical Mycology, vol. 34, no. 5, pp. 341–347, 1996