Upon completion of his Doctorate in Biomedical Science (BMS) Program at the University of California San Francisco (UCSF) in 1997, Jian-Dong Li worked as a junior faculty at UCSF where he focused on investigating the molecular pathogenesis of airway infectious diseases. This led to the identification of novel signaling mechanisms involved in the molecular pathogenesis of cystic fibrosis as well as development of an in vitro screening assay for mucus inhibitor. In 1998, Dr. Li joined the faculty of the House Ear Institute (HEI) at the University of Southern California where he served as the Chief of Signal Transduction Section. At HEI, Dr. Li identified the key signaling pathways involved in important human airway infectious and inflammatory diseases. In 2005, Dr. Li joined the University of Rochester Medical Center as a Tenured Full Professor. Since then, he and his collaborators have identified key signaling mechanisms including the novel inducible negative feedback loop involved in tight regulation of inflammatory and host innate defense response in infectious and inflammatory diseases. Dr. Li has also developed novel therapeutic agents for treating a variety of inflammatory and infectious diseases as well as heart failure.
Biography Updated on 4 October 2011